Results 101 to 110 of about 19,101 (227)

Prolonged exposure to artificial light and carcinogenesis: A systematic review of oncostatic mechanisms associated with melatonin pathways

open access: yesPhotochemistry and Photobiology, EarlyView.
Exposure to artificial light at night (ALAN), particularly at blue wavelengths, disrupts circadian rhythms by suppressing melatonin, thereby increasing cancer susceptibility. This systematic review consolidates evidence linking prolonged ALAN exposure to an elevated risk of breast and prostate tumors.
Gabriel Barboza   +4 more
wiley   +1 more source

Melanin in the Retinal Epithelium and Magnetic Sensing: A Review of Current Studies

open access: yesBiophysica
Coming in a variety of forms, melanin is one of the most abundant, stable, diverse, and evolutionarily ancient pigments found in living things in nature. These pigments often serve protective functions, typically well-adapted to their specific roles. One
Lidia Zueva   +3 more
doaj   +1 more source

DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization

open access: yeseLife, 2015
The circadian transcriptional repressors cryptochrome 1 (Cry1) and 2 (Cry2) evolved from photolyases, bacterial light-activated DNA repair enzymes. In this study, we report that while they have lost DNA repair activity, Cry1/2 adapted to protect genomic ...
Stephanie J Papp   +7 more
doaj   +1 more source

Localisation of the Putative Magnetoreceptive Protein Cryptochrome 1b in the Retinae of Migratory Birds and Homing Pigeons. [PDF]

open access: yesPLoS ONE, 2016
Cryptochromes are ubiquitously expressed in various animal tissues including the retina. Some cryptochromes are involved in regulating circadian activity.
Petra Bolte   +10 more
doaj   +1 more source

Genetic disruption of the core circadian clock impairs hippocampus-dependent memory [PDF]

open access: yes, 2014
Perturbing the circadian system by electrolytically lesioning the suprachiasmatic nucleus (SCN) or varying the environmental light:dark schedule impairs memory, suggesting that memory depends on the circadian system.
Chen, Xuanmao   +4 more
core   +2 more sources

Circadian regulation of reproduction and neoblast cell division in the catenulid flatworm Stenostomum virginianum (Platyhelminthes)

open access: yesPhotochemistry and Photobiology, EarlyView.
The circadian clock and melatonin coordinate homeostasis in many animals, yet their influence on reproduction and neoblast proliferation has only been shown in triclads. This study demonstrates that the early‐branching catenulid Stenostomum virginianum contains photoreceptive refractile bodies, synthesizes endogenous melatonin, and that exogenous ...
Daniel L. Stanton   +5 more
wiley   +1 more source

Comparison of retinol binding protein 1 with cone specific G-protein as putative effector molecules in cryptochrome signalling

open access: yesScientific Reports
Vision and magnetoreception in navigating songbirds are strongly connected as recent findings link a light dependent radical-pair mechanism in cryptochrome proteins to signalling pathways in cone photoreceptor cells. A previous yeast-two-hybrid screening
Chad Yee   +6 more
doaj   +1 more source

Circadian light-input pathways in Drosophila

open access: yesCommunicative & Integrative Biology, 2016
Light is the most important environmental cue to entrain the circadian clock in most animals. In the fruit fly Drosophila melanogaster, the light entrainment mechanisms of the clock have been well-studied.
Taishi Yoshii   +2 more
doaj   +1 more source

Der Blaulicht-Photorezeptor Cryptochrom 2 aus Arabidopsis thaliana: Lichtabhängige Phosphorylierung und Interaktionspartner in der Signaltransduktion [PDF]

open access: yes, 2003
Obwohl über die physiologische Bedeutung der pflanzlichen Cryptochrome bereits viel bekannt ist, und deren nahe Verwandte, die Photolyasen auch molekular sehr detailliert, einschließlich der Struktur auf atomarer Ebene, charakterisiert ...
Batschauer, Alfred Prof. Dr.   +1 more
core   +1 more source

Biomaterial Physical Cues as Gene Regulators for Cellular Agriculture

open access: yesAdvanced Genetics, Volume 7, Issue 2, June 2026.
This review elucidates how biomaterial physical cues—ranging from matrix stiffness to remote electromagnetic fields—serve as extrinsic regulators of gene expression in cellular agriculture. By identifying central mechanotransduction pathways that bridge physical inputs to genetic remodeling, the authors propose the “Material Genome” concept: a ...
Jianuo Liu, Ye Liu
wiley   +1 more source

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