Frontiers in Physiology, 2021 Circadian clocks prepare the organism to cyclic environmental changes in light, temperature, or food availability. Here, we characterized the master clock in the brain of a strongly photoperiodic insect, the aphid Acyrthosiphon pisum ...
Francesca Sara Colizzi +6 more
doaj +1 more source
Light Activation of the Phosphoinositide Cycle in Intrinsically Photosensitive Chicken Retinal Ganglion Cells [PDF]
, 2010 Purpose: In vertebrates, intrinsically photosensitive retinal ganglion cells (ipRGCs) acting as nonvisual photoreceptors transmit environmental illumination information to the brain, regulating diverse non–image-forming tasks.
Contin, Maria Ana +5 more
core +1 more source
Regulation and Identity of Florigen: Flowering Locus T Moves Center Stage [PDF]
, 2008 The transition from vegetative to reproductive growth is controlled by day length in many plant species. Day length is perceived in leaves and induces a systemic signal, called florigen, that moves through the phloem to the shoot apex.
Borden KL +11 more
core +2 more sources
Chronobiotics KL001 and KS15 Extend Lifespan and Modify Circadian Rhythms of Drosophila melanogaster
Clocks & Sleep, 2021 Chronobiotics are a group of drugs, which are utilized to modify circadian rhythms targeting clock-associated molecular mechanisms. The circadian clock is known as a controller of numerous processes in connection with aging.
Ilya A. Solovev +2 more
doaj +1 more source
Dynamics at the serine loop underlie differential affinity of cryptochromes for CLOCK:BMAL1 to control circadian timing. [PDF]
, 2020 Mammalian circadian rhythms are generated by a transcription-based feedback loop in which CLOCK:BMAL1 drives transcription of its repressors (PER1/2, CRY1/2), which ultimately interact with CLOCK:BMAL1 to close the feedback loop with ~24 hr periodicity ...
Abraham +70 more
core +3 more sources
Updated structure of Drosophila cryptochrome [PDF]
Nature, 2013 Arising from B. D. Zoltowski et al. , 396–399 (2011)10.1038/nature10618 Recently, we determined the X-ray crystal structure of full-length cryptochrome from Drosophila1. Here we report an improved model of the Drosophila cryptochrome (dCRY) structure that corrects errors in the original coordinates (
Levy, Colin +9 more
openaire +2 more sources
Frontiers in Physiology, 2020 Irises isolated from the eyes of diverse species constrict when exposed to light. Depending on species this intrinsic photomechanical transduction response (PMTR) requires either melanopsin or cryptochrome (CRY) photopigment proteins, generated by their ...
Joseph F. Margiotta, Marthe J. Howard
doaj +1 more source
Circadian rhythms and circadian clock gene homologs of complex alga Chromera velia
Frontiers in Plant Science, 2023 Most organisms on Earth are affected by periodic changes in their environment. The circadian clock is an endogenous device that synchronizes behavior, physiology, or biochemical processes to an approximately 24-hour cycle, allowing organisms to ...
Jitka Richtová +10 more
doaj +1 more source
Reaction mechanism of Drosophila cryptochrome [PDF]
Proceedings of the National Academy of Sciences, 2010 Cryptochrome (CRY) is a blue-light sensitive flavoprotein that functions as the primary circadian photoreceptor in Drosophila melanogaster . The mechanism by which it transmits the light signal to the core clock circuitry is not known.
Nuri, Ozturk +4 more
openaire +2 more sources
Reflections On Contributing To “Big Discoveries” About The Fly Clock: Our Fortunate Paths As Post-Docs With 2017 Nobel Laureates Jeff Hall, Michael Rosbash, And Mike Young [PDF]
, 2018 In the early 1980s Jeff Hall and Michael Rosbash at Brandeis University and Mike Young at Rockefeller University set out to isolate the period (per) gene, which was recovered in a revolutionary genetic screen by Ron Konopka and Seymour Benzer for mutants
Hardin, P. E. +2 more
core +4 more sources