Results 41 to 50 of about 9,815 (152)
Small‐Molecule Kinase Inhibitors Modulating Circadian Rhythms
Medicinal Research Reviews, EarlyView.ABSTRACT The circadian clock mechanism generates 24‐h rhythms crucial for regulating various physiological processes, and its dysregulation has been implicated in numerous diseases. In cells, the circadian clock operates through a transcriptional‐translational feedback loop, where phosphorylation plays a pivotal role in maintaining accurate circadian ...
Irene Castellino +3 more
wiley +1 more source
PLANTS, PEOPLE, PLANET, EarlyView.The increasing demand for sustainable food production requires innovative solutions that balance productivity, resource efficiency, and environmental impact. Vertical Farming Systems (VFSs) offer a promising approach; however, their high energy consumption remains challenging.
Alessio Dessì +11 more
wiley +1 more source
Photosynthetica, 2023 The light spectral composition acting through a set of photoreceptors, such as cryptochromes and phytochromes, plays an important role in maintaining sustainable photosynthesis.
V. KRESLAVSKI +7 more
doaj +1 more source
Light‐Inducible Activation of FGFR3 Facilitates Chondrocyte Maturation
Cell Proliferation, EarlyView.Light‐inducible activation of FGFR3 induced robust activation of MAPK signaling, promoting proliferation and collagen depositon in induced chondrocytes and prevent the degeneration of osteoarthritic chondrocytes.
Mengze Sun +5 more
wiley +1 more source
The FEBS Journal, EarlyView.Circadian disruption via constant light induces sex‐specific remodeling of the microbiome, lipid mediators, and immune responses. Females exhibit broader gut microbiota alterations, reduced jejunal oxylipins, increased hypothalamic N‐acylethanolamines, and a more inflammatory cytokine profile. Muscle responses are sex‐ and fiber type‐dependent: females
Pejman A. Pashaki +7 more
wiley +1 more source
International Journal of Laboratory Hematology, EarlyView.ABSTRACT Background Circadian clock disruption has emerged as a relevant axis in cancer; however, the expression patterns and diagnostic relevance of BMAL1 and CLOCK in multiple myeloma (MM) remain insufficiently defined. Methods BMAL1 and CLOCK mRNA expression was quantified by RT‐qPCR in bone marrow samples from 46 newly diagnosed MM patients and 13 ...
Hamide Albayrak +6 more
wiley +1 more source
Progress in Fishery SciencesThe circadian clock is an intrinsic timing mechanism that has evolved in organisms to adapt to the Earth's periodic diurnal changes. Cryptochrome and Period genes are pivotal in regulating the circadian system.
Wenhong YANG +6 more
doaj +1 more source
Expression of the Arabidopsis Sigma Factor SIG5 Is Photoreceptor and Photosynthesis Controlled
Plants, 2014 Two collections of Arabidopsis GAL4 enhancer trap lines were screened for light-intensity dependent reporter gene activation. Line N9313 was isolated for its strong light-intensity regulation.
Marina Mellenthin +3 more
doaj +1 more source
Orchid genome evolution and trait innovation
Journal of Integrative Plant Biology, EarlyView.Orchids became one of the world's most diverse plant groups through genome‐driven innovations, unique relationships with fungi and pollinators, and remarkable adaptability. This review explains the origins of orchids and the evolution of their distinctive life forms, flowers, and ecological strategies and highlights promising directions for future ...
Meng‐Yao Zeng +8 more
wiley +1 more source
Localisation of the Putative Magnetoreceptive Protein Cryptochrome 1b in the Retinae of Migratory Birds and Homing Pigeons. [PDF]
PLoS ONE, 2016 Cryptochromes are ubiquitously expressed in various animal tissues including the retina. Some cryptochromes are involved in regulating circadian activity.
Petra Bolte +10 more
doaj +1 more source