Results 11 to 20 of about 4,238 (147)

The structural and functional roles of the flavin cofactor FAD in mammalian cryptochromes

Frontiers in Molecular Biosciences, 2023
The importance of circadian rhythms in human health and disease calls for a thorough understanding of the underlying molecular machinery, including its key components, the flavin adenine dinucleotide (FAD)-containing flavoproteins cryptochrome 1 and 2 ...
Giulia Calloni, R. Martin Vabulas
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Roles of a Cryptochrome in Carbon Fixation and Sucrose Metabolism in the Liverwort Marchantia polymorpha

Cells, 2021
In vascular plants, cryptochromes acting as blue-light photoreceptors have various functions to adapt plants to the fluctuating light conditions on land, while the roles of cryptochromes in bryophytes have been rarely reported.
Tianhong Li, Li Zhang, Shengzhong Su, Sudi Li, Junchuan Zhang, Zhenming Yang, Zecheng Zuo   +6 more
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The Potorous CPD photolyase rescues a cryptochrome-deficient mammalian circadian clock. [PDF]

PLoS ONE, 2011
Despite the sequence and structural conservation between cryptochromes and photolyases, members of the cryptochrome/photolyase (flavo)protein family, their functions are divergent.
Inês Chaves, Romana M Nijman, Magdalena A Biernat, Monika I Bajek, Karl Brand, António Carvalho da Silva, Shoko Saito, Kazuhiro Yagita, André P M Eker, Gijsbertus T J van der Horst   +9 more
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Discovery of a small molecule that selectively destabilizes Cryptochrome 1 and enhances life span in p53 knockout mice

Nature Communications, 2022
Cryptochromes are transcriptional regulators of the circadian clock in mammals, and genetic loss of cryptochromes reduces p53-associated cancer risk in mice.
Seref Gul, Yasemin Kubra Akyel, Zeynep Melis Gul, Safak Isin, Onur Ozcan, Tuba Korkmaz, Saba Selvi, Ibrahim Danis, Ozgecan Savlug Ipek, Fatih Aygenli, Ali Cihan Taskin, Büşra Aytül Akarlar, Nurhan Ozlu, Nuri Ozturk, Narin Ozturk, Durişehvar Özer Ünal, Mustafa Guzel, Metin Turkay, Alper Okyar, Ibrahim Halil Kavakli   +19 more
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CRY1 Gene Polymorphism and Racing Performance of Homing Pigeons

Animals, 2021
Cryptochromes (CRY) are the family of proteins proposed as the putative magnetoreceptor molecules. In birds, among others in pigeons, CRY1 is widely expressed in a retina.
Andrzej Dybus, Hanna Kulig, Yu-Hsiang Yu, Ruben Lanckriet, Witold Proskura, Yeong-Hsiang Cheng   +5 more
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Structural and Chemical Biology Approaches Reveal Isoform-Selective Mechanisms of Ligand Interactions in Mammalian Cryptochromes

Frontiers in Physiology, 2022
Cryptochromes (CRYs) are core components of the circadian feedback loop in mammals, which regulates circadian rhythmicity in a variety of physiological processes including sleep–wake cycles and metabolism.
Simon Miller, Tsuyoshi Hirota
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Human cryptochrome-1 confers light independent biological activity in transgenic Drosophila correlated with flavin radical stability.

PLoS ONE, 2012
Cryptochromes are conserved flavoprotein receptors found throughout the biological kingdom with diversified roles in plant development and entrainment of the circadian clock in animals.
Jacqueline Vieira, Alex R Jones, Antoine Danon, Michiyo Sakuma, Nathalie Hoang, David Robles, Shirley Tait, Derren J Heyes, Marie Picot, Taishi Yoshii, Charlotte Helfrich-Förster, Guillaume Soubigou, Jean-Yves Coppee, André Klarsfeld, Francois Rouyer, Nigel S Scrutton, Margaret Ahmad   +16 more
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The World of Algae Reveals a Broad Variety of Cryptochrome Properties and Functions

Frontiers in Plant Science, 2021
Algae are photosynthetic eukaryotic (micro-)organisms, lacking roots, leaves, and other organs that are typical for land plants. They live in freshwater, marine, or terrestrial habitats.
Jan Petersen, Anxhela Rredhi, Julie Szyttenholm, Sabine Oldemeyer, Tilman Kottke, Tilman Kottke, Maria Mittag   +6 more
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Crosstalk between Photoreceptor and Sugar Signaling Modulates Floral Signal Transduction

Frontiers in Physiology, 2017
Over the past decade, integrated genetic, cellular, proteomic and genomic approaches have begun to unravel the surprisingly crosstalk between photoreceptors and sugar signaling in regulation of floral signal transduction.
Ianis G. Matsoukas
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Hypothesis on the Role of Cryptochromes in Inflammation and Subarachnoid Hemorrhage Outcome

Frontiers in Neurology, 2017
We have recently found that the temperature variability (TV) in the day–night cycle may predict the mean intracranial pressure in the following 24 h (ICP24) in subarachnoid hemorrhage (SAH) patients under multimodality monitoring, sedation, and ...
Adriano Barreto Nogueira, Adriano Barreto Nogueira, Ariel Barreto Nogueira, José Carlos Esteves Veiga, Manoel Jacobsen Teixeira, Manoel Jacobsen Teixeira   +5 more
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