Results 1 to 10 of about 83,239 (230)

Fluconazole Monotherapy Is a Suboptimal Option for Initial Treatment of Cryptococcal Meningitis Because of Emergence of Resistance [PDF]

open access: yesmBio, 2019
Cryptococcal meningitis is a lethal disease with few therapeutic options. Induction therapy with fluconazole has been consistently demonstrated to be associated with suboptimal microbiological and clinical outcomes. Exposure to fluconazole causes dynamic
William Hope   +14 more
doaj   +3 more sources

Obligate sexual reproduction of a homothallic fungus closely related to the Cryptococcus pathogenic species complex

open access: yeseLife, 2022
Sexual reproduction is a ubiquitous, ancient eukaryotic trait. While most sexual organisms have to find a mating partner, species as diverse as animals, plants, and fungi have evolved the ability to reproduce sexually without requiring another individual.
Andrew Ryan Passer   +11 more
doaj   +1 more source

Neuroimaging of Cryptococcal Meningitis in Patients without Human Immunodeficiency Virus: Data from a Multi-Center Cohort Study

open access: yesJournal of Fungi, 2023
Background: A clearer understanding is needed about the use of brain MRI in non-HIV patients with cryptococcal meningitis. Methods: Cerebral CT and MRI were studied in 62 patients in a multicenter study of cryptococcal meningitis in non-HIV patients.
Seher H. Anjum   +5 more
doaj   +1 more source

Cryptococcal chest wall mass and rib osteomyelitis associated with the use of fingolimod: A case report and literature review

open access: yesFrontiers in Medicine, 2022
Being introduced in 2010, fingolimod was among the first oral therapies for relapsing multiple sclerosis (MS). Since that time, postmarketing surveillance has noted several case reports of various cryptococcal infections associated with fingolimod use ...
Kent Carpenter   +10 more
doaj   +1 more source

Opportunistic Fungal Infections in Immunocompromised Patients of a Tertiary Care Centre, Amritsar, India [PDF]

open access: yesNational Journal of Laboratory Medicine, 2022
Introduction: The incidence of opportunistic fungal infections has increased considerably in recent years. The clinical manifestations of these infections are non specific, and laboratory methods generally cannot diagnose infection at an initial ...
PAVNEET KAUR   +2 more
doaj   +1 more source

Conflicting interests in the pathogen-host tug of war : fungal micronutrient scavenging versus mammalian nutritional immunity [PDF]

open access: yes, 2014
Funding: The authors are supported by the European Research Council (STRIFE project funded on grant number ERC-2009-AdG-249793, http://erc.europa.eu). AJPB is also supported by the Wellcome Trust (grant numbers 080088, 097377, www.wellcome.ac.uk) and the
Ballou, Elizabeth R   +3 more
core   +8 more sources

Cryptococcal meningitis post-covid-19 infection: Immunomodulation, a double-edged sword

open access: yesJournal of Infection in Developing Countries, 2023
Cryptococcal meningitis is an opportunistic infection associated with altered immunity. Immunomodulatory agent use in severe coronavirus disease 2019 (COVID-19) may predispose such infections.
Hilal W Abdessamad   +10 more
doaj   +1 more source

Cerebral Cryptococcosis Associated with CD4+ T-lymphocytopenia in Non-HIV Patients after SARS-CoV-2 Infection: Case Series in a Specialized Institute in Lima, Peru

open access: yesTropical Medicine and Infectious Disease, 2023
Cases of cryptococcosis have been reported in patients with COVID-19. The majority are in patients with severe symptoms or who received immunosuppressants. However, there is still no clear association between COVID-19 and cryptococcosis.
Juana M. Huamani-Córdova   +6 more
doaj   +1 more source

Exogenous cryptococcal endophthalmitis in an immunocompetent patient

open access: yesTaiwan Journal of Ophthalmology, 2023
We describe a case of exogenous cryptococcal endophthalmitis without central nervous system (CNS) involvement or systemic infection in an immunocompetent patient.
Daniel Zhu   +7 more
doaj   +1 more source

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