Results 1 to 10 of about 83,746 (268)

Fluconazole Monotherapy Is a Suboptimal Option for Initial Treatment of Cryptococcal Meningitis Because of Emergence of Resistance [PDF]

mBio, 2019
Cryptococcal meningitis is a lethal disease with few therapeutic options. Induction therapy with fluconazole has been consistently demonstrated to be associated with suboptimal microbiological and clinical outcomes. Exposure to fluconazole causes dynamic
William Hope, Neil R. H. Stone, Adam Johnson, Laura McEntee, Nicola Farrington, Anahi Santoro-Castelazo, Xuan Liu, Anita Lucaci, Margaret Hughes, Jason D. Oliver, Charles Giamberardino, Sayoki Mfinanga, Thomas S. Harrison, John R. Perfect, Tihana Bicanic   +14 more
doaj   +3 more sources

Oftalmoplejía internuclear bilateral como rara presentación inicial de meningitis criptocócica [PDF]

Revista de la Facultad de Ciencias Médicas de Córdoba
Introducción. La meningitis criptocócica (MC) se asocia frecuentemente a pacientes inmunocomprometidos, específicamente en infección por VIH, con una alta mortalidad.
Raymundo Solís-Gómez, Itzel A. Hernández-Dehesa, Aztlani Adan-Ruiz, Adrián F. Sánchez-Cruz, Eduardo Argüelles-González   +4 more
doaj   +2 more sources

Opportunistic Fungal Infections in Immunocompromised Patients of a Tertiary Care Centre, Amritsar, India [PDF]

National Journal of Laboratory Medicine, 2022
Introduction: The incidence of opportunistic fungal infections has increased considerably in recent years. The clinical manifestations of these infections are non specific, and laboratory methods generally cannot diagnose infection at an initial ...
PAVNEET KAUR, SIMRANPREET KAUR, ARVINDER SINGH SOOD   +2 more
doaj   +1 more source

Direct Inhibition of T-Cell Responses by the Cryptococcus Capsular Polysaccharide Glucuronoxylomannan [PDF]

, 2006
The major virulence factor of the pathogenic fungi Cryptococcus neoformans and C. gattii is the capsule. Glucuronoxylomannan (GXM), the major component of the capsule, is a high-molecular-weight polysaccharide that is shed during cryptococcosis and can ...
Lam, Jennifer S, Levitz, Stuart M, Yauch, Lauren E   +2 more
core   +11 more sources

Postrenal transplant disseminated cryptococcosis presenting as a syndrome of inappropriate antidiuretic hormone secretion - A case report

Indian Journal of Transplantation, 2022
Cryptococcosis is the most common invasive fungal infection to involve the central nervous system in the posttransplant period. Cryptococcal meningitis, which constitutes disseminated cryptococcosis, can present with nonspecific signs and symptoms ...
Sandhya Suresh, Abhijit Konnur, Sishir Gang   +2 more
doaj   +1 more source

Cerebral Venous Thrombosis due to Cryptococcus in a Multiple Sclerosis Patient on Fingolimod

Case Reports in Neurology, 2022
Fingolimod is a disease-modifying treatment utilized in the treatment of relapsing-remitting multiple sclerosis. Fingolimod has been associated with an increased risk in herpes simplex and varicella infection in clinical trials.
Joel A. Kammeyer, Nicole M. Lehmann
doaj   +1 more source

Exogenous cryptococcal endophthalmitis in an immunocompetent patient

Taiwan Journal of Ophthalmology, 2023
We describe a case of exogenous cryptococcal endophthalmitis without central nervous system (CNS) involvement or systemic infection in an immunocompetent patient.
Daniel Zhu, Ravneet Rai, Elzbieta Mechel, Paras P Shah, Maggie Hymowitz, Victoria Rohring, Isha Cheela, C Michael Samson   +7 more
doaj   +1 more source

Dendritic Cells: Multifunctional Roles in Host Defenses to Cryptococcus Infections

Journal of Fungi, 2023
Fungal infections are an increasingly growing public health concern, and Cryptococcus is one of the most problematic fungal organisms causing substantial mortality and morbidity worldwide.
Kristie D. Goughenour, Ayesha S. Nair, Jintao Xu, Michal A. Olszewski, Karen L. Wozniak   +4 more
doaj   +1 more source

Combination Therapy for HIV-Associated Cryptococcal Meningitis—A Success Story

Journal of Fungi, 2021
Cryptococcal meningitis is the leading cause of adult meningitis in patients with HIV, and accounts for 15% of all HIV-related deaths in sub-Saharan Africa.
William J. Hurt, Thomas S. Harrison, Síle F. Molloy, Tihana A. Bicanic   +3 more
doaj   +1 more source

Automated Analysis of Cryptococcal Macrophage Parasitism Using GFP-Tagged Cryptococci [PDF]

, 2010
The human fungal pathogens Cryptococcus neoformans and C. gattii cause life-threatening infections of the central nervous system. One of the major characteristics of cryptococcal disease is the ability of the pathogen to parasitise upon phagocytic immune
A Casadevall, A Idnurm, AL Goldstein, B Bolanos, BJ Park, C Charlier, C Luberto, C Monari, CE Cross, DA Bobak, DL Goldman, DL Goldman, DL Oliveira, DL Toffaletti, E Brummer, EJ Byrnes 3rd, F Chretien, FM Griffin Jr, G Hu, GD Campbell, GS Bulmer, GS Bulmer, H Lee, H Ma, H Ma, H Ma, HF Nadrous, J Livet, Julian C. Rutherford, K Voelz, Kerstin Voelz, Kirsten Nielsen, L MacDougall, LA Knodler, LH Okagaki, M Alvarez, M Alvarez, M Alvarez, M Alvarez, M Del Poeta, M Feldmesser, M Feldmesser, M Shi, MC Lorenz, MF Miller, NC Shaner, P Ralph, R Bajpai, R Santangelo, R Velagapudi, RD Diamond, Robin C. May, S Geunes-Boyer, SC Tucker, SE Kidd, Simon A. Johnston, SM Levitz, TA Missall, TB Kechichian, TG Mitchell, TG Mitchell, TR Kozel, TW Christianson, X Dong, X Shao   +64 more
core   +9 more sources