Results 31 to 40 of about 108,443 (306)
Dating the Cryptococcus gattii Dispersal to the North American Pacific Northwest. [PDF]
The emergence of Cryptococcus gattii, previously regarded as a predominantly tropical pathogen, in the temperate climate of the North American Pacific Northwest (PNW) in 1999 prompted several questions.
Bodo Wanke+15 more
core +3 more sources
In Cryptococcus neoformans, nearly all genes are interrupted by small introns. In recent years, genome annotation and genetic analysis have illuminated the major roles these introns play in the biology of this pathogenic yeast. Introns are necessary for gene expression and alternative splicing can regulate gene expression in response to environmental ...
openaire +7 more sources
Phenotypic Switching of Cryptococcus neoformans and Cryptococcus gattii [PDF]
Microorganisms that live in fluctuating environments must constantly adapt their behavior to survive. The host constitutes an important microenvironment in opportunistic and primary fungal pathogens like Cryptococcus neoformans (C. neoformans) and Cryptococcus gattii (C. gattii).
Bettina C. Fries, Neena Jain
openaire +3 more sources
Diagnostic and mortality outcomes in a cohort of adult meningitis suspects in KwaZulu-Natal
Background: The clinical value of lumbar puncture (LP) in settings with a high human immunodeficiency virus (HIV) prevalence has not been well defined. Methods: We performed a retrospective chart review in 394 adults undergoing LP at a single regional ...
Onke Nonkala+2 more
doaj +1 more source
Titan cell production in Cryptococcus neoformans reshapes the cell wall and capsule composition during infection [PDF]
This work was supported by the National Institutes of Health (R01AI080275 and R21AI22352), the NIH Fogarty International Center (R25TW009345), the University of Minnesota Center for Translational Science Institute (UL1TR000114), Wellcome Trust (086827 ...
Gow, Neil A R+5 more
core +1 more source
The role of the host—Neutrophil biology
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple+4 more
wiley +1 more source
Creatinine metabolism in Cryptococcus neoformans and Cryptococcus bacillisporus [PDF]
The pathogenic species of Cryptococcus, C. neoformans and C. bacillisporus, utilized creatinine as a source of nitrogen but not of carbon. Chromatographic and autoradiographic studies suggest that creatinine metabolism in both species involves a single step resulting in the production of methylhydantoin and ammonia. The enzyme responsible for this step,
I Polacheck, K J Kwon-Chung
openaire +3 more sources
CAQ Corner: Immune‐mediated complications
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley +1 more source
Brewers lost in wild yeast nomenclature
In recent decades many changes have been adopted in the fungal nomenclature, including the names of yeasts, to achieve a more natural and uniform systematics.
Lucie Kyselová+3 more
doaj +1 more source
Vomocytosis: Too Much Booze, Base, or Calcium? [PDF]
Macrophages are well known for their phagocytic activity and their role in innate immune responses. Macrophages eat non-self particles, via a variety of mechanisms, and typically break down internalized cargo into small macromolecules.
Aaron+98 more
core +2 more sources