Clinical Case Reports, 2021 In immunocompromised patients, including patients with AIDS, with neurologic complaints, we propose including Cryptococcus meningoencephalitis in the differential diagnoses when the butterfly pattern is encountered on MRI.
Mary Henary, Jennifer Oster, Antonio Liu
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Differential antifungal activity of human and cryptococcal melanins with structural discrepancies [PDF]
, 2017 Indexación: Scopus.Melanin is a pigment found in all biological kingdoms, and plays a key role in protection against ultraviolet radiation, oxidizing agents, and ionizing radiation damage. Melanin exerts an antimicrobial activity against bacteria, fungi,
Correa, N. +8 more
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Cryptococcus neoformans chitin synthase 3 plays a critical role in dampening host inflammatory responses [PDF]
, 2020 Cryptococcus neoformans is the most common disseminated fungal pathogen in AIDS patients, resulting in ∼200,000 deaths each year. There is a pressing need for new treatments for this infection, as current antifungal therapy is hampered by toxicity and/or
Hole, Camaron R +3 more
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Immunotherapy of Cryptococcus infections [PDF]
Clinical Microbiology and Infection, 2012 Despite appropriate antifungal treatment, the management of cryptococcal disease remains challenging, especially in immunocompromised patients, such as human immunodeficiency virus-infected individuals and solid organ transplant recipients. During the past two decades, our knowledge of host immune responses against Cryptococcus spp.
Thomas J. Walsh +1 more
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Virulence, 2020 The two leading yeast pathogens of humans, Candida albicans and Cryptococcus neoformans, cause systemic infections in >1.4 million patients worldwide with mortality rates approaching 75%.
Naomi Lyons +7 more
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Invasion of the central nervous system by Cryptococcus neoformans requires a secreted fungal metalloprotease. [PDF]
, 2014 UnlabelledCryptococcus spp. cause life-threatening fungal infection of the central nervous system (CNS), predominantly in patients with a compromised immune system.
Bautos, Jennifer M +7 more
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Capsule-deficient cryptococcal meningitis: A diagnostic conundrum
Journal of Global Infectious Diseases, 2022 Cryptococcosis is a serious systemic mycosis. Its incidence has escalated in the past four decades. Cryptococcus neoformans causes localized or disseminated infection in immunocompromised and immunocompetent patients.
Trupti Shende +6 more
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Cryptococcus, Pathological observations of five autopsy cases and one biopsy case [PDF]
, 1959 Pathologic, anatomical, and histological findings of 5 autopsy cases and one biopsy case of cryptococcosis have been described. Macroscopically the foci of the lung are grayish white or yellowish white in color and range in size from the small acinous ...
Inohara, Tsuyoshi +5 more
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Pharmacokinetics of isavuconazole in healthy cats after oral and intravenous administration
Journal of Veterinary Internal Medicine, 2022 Background Isavuconazole is a triazole antifungal drug that has shown good efficacy in human patients. Absorption and pharmacokinetics have not been evaluated in cats.
Dennis J. Woerde +2 more
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Deep RNA-Seq profile reveals biodiversity, plant-microbe interactions and a large family of NBS-LRR resistance genes in walnut (Juglans regia) tissues. [PDF]
, 2016 Deep RNA-Seq profiling, a revolutionary method used for quantifying transcriptional levels, often includes non-specific transcripts from other co-existing organisms in spite of stringent protocols. Using the recently published walnut genome sequence as a
Britton, Monica +3 more
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