Results 51 to 60 of about 108,443 (306)

Cryptococcaemia in a Jamaican Cohort

open access: yesCaribbean Medical Journal, 2022
Background: The study objective was to describe the clinical features associated with cryptococcaemia in a Jamaican cohort and determine associated risk factors and outcomes.
Camille-Ann Thoms-Rodriguez
doaj  

Pulmonary Macrophage and Dendritic Cell Responses to Cryptococcus neoformans

open access: yesFrontiers in Cellular and Infection Microbiology, 2020
The fungal pathogen Cryptococcus neoformans can cause life-threatening infections in immune compromised individuals. This pathogen is typically acquired via inhalation, and enters the respiratory tract.
Benjamin N. Nelson   +2 more
semanticscholar   +1 more source

Polymorphic α‐Glucans as Structural Scaffolds in Cryptococcus Cell Walls for Chitin, Capsule, and Melanin: Insights From 13C and 1H Solid‐State NMR

open access: yesAngewandte Chemie, EarlyView.
Cryptococcus neoformans cell wall α‐1,3‐glucans as dual anchors for melanin and capsule: Solid‐state NMR of intact C. neoformans cells reveals five forms of α‐1,3‐glucans that structurally bridge melanin and capsule layers. These polysaccharides interact with chitin, chitosan, and β‐glucans to create a molecular scaffold that underlies virulence and ...
Ankur Ankur   +11 more
wiley   +2 more sources

Butterfly lesion on MRI: Cryptococcus meningoencephalitis with unusual imaging in a patient with AIDS

open access: yesClinical Case Reports, 2021
In immunocompromised patients, including patients with AIDS, with neurologic complaints, we propose including Cryptococcus meningoencephalitis in the differential diagnoses when the butterfly pattern is encountered on MRI.
Mary Henary, Jennifer Oster, Antonio Liu
doaj   +1 more source

RNA interference screening reveals host CaMK4 as a regulator of cryptococcal uptake and pathogenesis [PDF]

open access: yes, 2017
Cryptococcus neoformans , the causative agent of cryptococcosis, is an opportunistic fungal pathogen that kills over 200,000 individuals annually. This yeast may grow freely in body fluids, but it also flourishes within host cells.
Doering, Tamara L   +4 more
core   +2 more sources

Immunotherapy of Cryptococcus infections [PDF]

open access: yesClinical Microbiology and Infection, 2012
Despite appropriate antifungal treatment, the management of cryptococcal disease remains challenging, especially in immunocompromised patients, such as human immunodeficiency virus-infected individuals and solid organ transplant recipients. During the past two decades, our knowledge of host immune responses against Cryptococcus spp.
Thomas J. Walsh   +1 more
openaire   +2 more sources

Tobacco Hornworm (Manduca sexta) caterpillars as a novel host model for the study of fungal virulence and drug efficacy

open access: yesVirulence, 2020
The two leading yeast pathogens of humans, Candida albicans and Cryptococcus neoformans, cause systemic infections in >1.4 million patients worldwide with mortality rates approaching 75%.
Naomi Lyons   +7 more
doaj   +1 more source

Rim Pathway-Mediated Alterations in the Fungal Cell Wall Influence Immune Recognition and Inflammation [PDF]

open access: yes, 2017
ACKNOWLEDGMENTS We acknowledge Jennifer Lodge, Woei Lam, and Rajendra Upadhya for developing and sharing the chitin and chitosan MTBH assay. We thank Todd Brennan of Duke University for providing MyD88-deficient mice.
Carol Munro   +8 more
core   +3 more sources

Pathogen-derived extracellular vesicles mediate virulence in the fatal human pathogen Cryptococcus gattii

open access: yesNature Communications, 2018
The Pacific Northwest outbreak of cryptococcosis, caused by a near-clonal lineage of the fungal pathogen Cryptococcus gattii, represents the most significant cluster of life-threatening fungal infections in otherwise healthy human hosts currently known ...
E. Bielska   +5 more
semanticscholar   +1 more source

Capsule-deficient cryptococcal meningitis: A diagnostic conundrum

open access: yesJournal of Global Infectious Diseases, 2022
Cryptococcosis is a serious systemic mycosis. Its incidence has escalated in the past four decades. Cryptococcus neoformans causes localized or disseminated infection in immunocompromised and immunocompetent patients.
Trupti Shende   +6 more
doaj   +1 more source

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