Results 51 to 60 of about 83,239 (230)

Hydrogel Confinement Strategies for 3D Cell Culture in Microfluidic Systems

open access: yesAdvanced Materials Technologies, EarlyView.
Hydrogel confinement structures are key to organizing 3D cell cultures in microfluidic devices. This review classifies five structural strategies (micropillar, phaseguide, porous membrane, stepped‐height, and support‐free) and examines their trade‐offs alongside fabrication methods.
Soohyun Kim, Min Seok Lee, Sung Kyun Lee
wiley   +1 more source

Phenotypic Switching of Cryptococcus neoformans and Cryptococcus gattii [PDF]

open access: yesMycopathologia, 2008
Microorganisms that live in fluctuating environments must constantly adapt their behavior to survive. The host constitutes an important microenvironment in opportunistic and primary fungal pathogens like Cryptococcus neoformans (C. neoformans) and Cryptococcus gattii (C. gattii).
Neena, Jain, Bettina C, Fries
openaire   +2 more sources

A Genomic Catalog of Migratory Microbiomes from Wild Birds across China's Habitats

open access: yesAdvanced Science, EarlyView.
ABSTRACT Migratory birds play an important role in the spread of antimicrobial resistance (AMR); however, gaps in surveillance data from vital regions along migratory flyways across China limit the detection of emergent threats. Here, we assembled 340 metagenomes from 52 bird species covering 11 provincial administrative districts in China, presenting ...
Yanan Wang   +13 more
wiley   +1 more source

Creatinine metabolism in Cryptococcus neoformans and Cryptococcus bacillisporus [PDF]

open access: yesJournal of Bacteriology, 1980
The pathogenic species of Cryptococcus, C. neoformans and C. bacillisporus, utilized creatinine as a source of nitrogen but not of carbon. Chromatographic and autoradiographic studies suggest that creatinine metabolism in both species involves a single step resulting in the production of methylhydantoin and ammonia. The enzyme responsible for this step,
I, Polacheck, K J, Kwon-Chung
openaire   +2 more sources

Unveiling bone marrow cryptococcosis in an immunocompetent child: A rare case presentation

open access: yesIndian Journal of Pathology and Microbiology
Cryptococcal infection is less common in immunocompetent hosts and almost always occurs in the setting of HIV disease. Disseminated Cryptococcosis in a child is a fatal condition and often requires a prompt diagnosis and appropriate antifungal therapy to
Shalini Singh   +3 more
doaj   +1 more source

Cryptococcaemia in a Jamaican Cohort

open access: yesCaribbean Medical Journal, 2022
Background: The study objective was to describe the clinical features associated with cryptococcaemia in a Jamaican cohort and determine associated risk factors and outcomes.
Camille-Ann Thoms-Rodriguez
doaj  

Diagnostic and mortality outcomes in a cohort of adult meningitis suspects in KwaZulu-Natal

open access: yesSouthern African Journal of Infectious Diseases, 2018
Background: The clinical value of lumbar puncture (LP) in settings with a high human immunodeficiency virus (HIV) prevalence has not been well defined. Methods: We performed a retrospective chart review in 394 adults undergoing LP at a single regional ...
Onke Nonkala   +2 more
doaj   +1 more source

The power of many: when genetics met yeasts and high‐throughput

open access: yesBiological Reviews, EarlyView.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source

Cryptococcus–Epithelial Interactions [PDF]

open access: yesJournal of Fungi, 2017
The fungal pathogen, Cryptococcus neoformans, causes devastating levels of morbidity and mortality. Infections with this fungus tend to be predominantly in immunocompromised individuals, such as those with HIV. Infections initiate with inhalation of cryptococcal cells and entry of the pathogen into the lungs. The bronchial epithelial cells of the upper
openaire   +3 more sources

Cytokine dynamics in the blood and cerebrospinal fluid of HIV/AIDS patients with cryptococcal meningitis receiving antifungal therapy

open access: yesFrontiers in Cellular and Infection Microbiology
BackgroundCytokines in the serum and cerebrospinal fluid (CSF) are critical to the pathogenesis of HIV-associated cryptococcal meningitis (HCM). Previous studies focused on baseline cytokine levels, but changes during antifungal therapy are underexplored.
Rui Su   +7 more
doaj   +1 more source

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