Results 51 to 60 of about 108,443 (306)
Cryptococcaemia in a Jamaican Cohort
Background: The study objective was to describe the clinical features associated with cryptococcaemia in a Jamaican cohort and determine associated risk factors and outcomes.
Camille-Ann Thoms-Rodriguez
doaj
Pulmonary Macrophage and Dendritic Cell Responses to Cryptococcus neoformans
The fungal pathogen Cryptococcus neoformans can cause life-threatening infections in immune compromised individuals. This pathogen is typically acquired via inhalation, and enters the respiratory tract.
Benjamin N. Nelson+2 more
semanticscholar +1 more source
Cryptococcus neoformans cell wall α‐1,3‐glucans as dual anchors for melanin and capsule: Solid‐state NMR of intact C. neoformans cells reveals five forms of α‐1,3‐glucans that structurally bridge melanin and capsule layers. These polysaccharides interact with chitin, chitosan, and β‐glucans to create a molecular scaffold that underlies virulence and ...
Ankur Ankur+11 more
wiley +2 more sources
In immunocompromised patients, including patients with AIDS, with neurologic complaints, we propose including Cryptococcus meningoencephalitis in the differential diagnoses when the butterfly pattern is encountered on MRI.
Mary Henary, Jennifer Oster, Antonio Liu
doaj +1 more source
RNA interference screening reveals host CaMK4 as a regulator of cryptococcal uptake and pathogenesis [PDF]
Cryptococcus neoformans , the causative agent of cryptococcosis, is an opportunistic fungal pathogen that kills over 200,000 individuals annually. This yeast may grow freely in body fluids, but it also flourishes within host cells.
Doering, Tamara L+4 more
core +2 more sources
Immunotherapy of Cryptococcus infections [PDF]
Despite appropriate antifungal treatment, the management of cryptococcal disease remains challenging, especially in immunocompromised patients, such as human immunodeficiency virus-infected individuals and solid organ transplant recipients. During the past two decades, our knowledge of host immune responses against Cryptococcus spp.
Thomas J. Walsh+1 more
openaire +2 more sources
The two leading yeast pathogens of humans, Candida albicans and Cryptococcus neoformans, cause systemic infections in >1.4 million patients worldwide with mortality rates approaching 75%.
Naomi Lyons+7 more
doaj +1 more source
Rim Pathway-Mediated Alterations in the Fungal Cell Wall Influence Immune Recognition and Inflammation [PDF]
ACKNOWLEDGMENTS We acknowledge Jennifer Lodge, Woei Lam, and Rajendra Upadhya for developing and sharing the chitin and chitosan MTBH assay. We thank Todd Brennan of Duke University for providing MyD88-deficient mice.
Carol Munro+8 more
core +3 more sources
The Pacific Northwest outbreak of cryptococcosis, caused by a near-clonal lineage of the fungal pathogen Cryptococcus gattii, represents the most significant cluster of life-threatening fungal infections in otherwise healthy human hosts currently known ...
E. Bielska+5 more
semanticscholar +1 more source
Capsule-deficient cryptococcal meningitis: A diagnostic conundrum
Cryptococcosis is a serious systemic mycosis. Its incidence has escalated in the past four decades. Cryptococcus neoformans causes localized or disseminated infection in immunocompromised and immunocompetent patients.
Trupti Shende+6 more
doaj +1 more source