Pitfalls associated with the use of molecular diagnostic panels in the diagnosis of cryptococcal meningitis [PDF]
We report the case of a kidney transplantation patient on chronic immunosuppressive therapy presenting with subacute meningitis. The final diagnosis of cryptococcal meningitis was delayed due to 2 false-negative cryptococcal results on a molecular ...
Burnham, Carey-Ann+5 more
core +2 more sources
Deep RNA-Seq profile reveals biodiversity, plant-microbe interactions and a large family of NBS-LRR resistance genes in walnut (Juglans regia) tissues. [PDF]
Deep RNA-Seq profiling, a revolutionary method used for quantifying transcriptional levels, often includes non-specific transcripts from other co-existing organisms in spite of stringent protocols. Using the recently published walnut genome sequence as a
Britton, Monica+3 more
core +2 more sources
Cryptococcus neoformans chitin synthase 3 plays a critical role in dampening host inflammatory responses [PDF]
Cryptococcus neoformans is the most common disseminated fungal pathogen in AIDS patients, resulting in ∼200,000 deaths each year. There is a pressing need for new treatments for this infection, as current antifungal therapy is hampered by toxicity and/or
Hole, Camaron R+3 more
core +2 more sources
There are approximately 1 million cryptococcal infections per year among HIV+ individuals, resulting in nearly 625,000 deaths. Cryptococcus neoformans and Cryptococcus gattii are the two most common species that cause human cryptococcosis.
Shan Hu+8 more
semanticscholar +1 more source
Pharmacokinetics of isavuconazole in healthy cats after oral and intravenous administration
Background Isavuconazole is a triazole antifungal drug that has shown good efficacy in human patients. Absorption and pharmacokinetics have not been evaluated in cats.
Dennis J. Woerde+2 more
doaj +1 more source
Life Cycle of Cryptococcus neoformans.
Cryptococcus neoformans is a ubiquitous environmental fungus and an opportunistic pathogen that causes fatal cryptococcal meningitis. Advances in genomics, genetics, and cellular and molecular biology of C.
Youbao Zhao+3 more
semanticscholar +1 more source
Cryptococcal choroiditis in advanced AIDS with clinicopathologic correlation. [PDF]
PurposeTo describe a case of disseminated cryptococcal meningitis with multifocal choroiditis and provide optical coherence tomography (OCT) findings correlated with described histopathology in a patient with advanced acquired immunodeficiency syndrome ...
Aderman, Christopher M+5 more
core +2 more sources
Characteristics and Outcomes of Cryptococcosis among Patients with and without COVID-19
The effect of COVID-19 on the risk and prognosis of cryptococcosis is unclear. We compared the characteristics and outcomes of cryptococcosis in patients with and without COVID-19.
Daniel B. Chastain+7 more
doaj +1 more source
Galactoxylomannans of Cryptococcus neoformans [PDF]
Galactoxylomannans (GalXMs) from single isolates of Cryptococcus neoformans serotypes A, B, and D were isolated from culture supernatants and then purified by affinity, ion-exchange, and gel-filtration chromatography. GalXMs are a group of closely related complex polysaccharides.
P G James, Robert Cherniak
openaire +3 more sources
Cryptococcus, Pathological observations of five autopsy cases and one biopsy case [PDF]
Pathologic, anatomical, and histological findings of 5 autopsy cases and one biopsy case of cryptococcosis have been described. Macroscopically the foci of the lung are grayish white or yellowish white in color and range in size from the small acinous ...
Inohara, Tsuyoshi+5 more
core +1 more source