Results 41 to 50 of about 54,149 (255)

Evaluación de varias técnicas de extracción de ADN de Cryptococcus spp. a partir de muestras ambientales.

Biomédica: revista del Instituto Nacional de Salud, 2004
El género Cryptococcus comprende, al menos, 38 especies, pero sólo 3 se han informado como patógenas para el hombre y los animales: Cryptococcus laurentii, Cryptococcus albidus y Cryptococcus neoformans; esta última es la más frecuente.
Alexandra Castañeda, Juan McEwen, Marylin Hidalgo, Elizabeth Castañeda   +3 more
doaj   +1 more source

Three phylogenetic groups have driven the recent population expansion of Cryptococcus neoformans

Nature Communications, 2019
Cryptococcus neoformans (C. neoformans var. grubii) is an environmentally acquired pathogen causing 181,000 HIV-associated deaths each year. We sequenced 699 isolates, primarily C.
P. M. Ashton, L. Thanh, P. Trieu, D. V. Anh, Nguyen Mai Trinh, J. Beardsley, J. Beardsley, Freddie M Kibengo, W. Chierakul, D. Dance, D. Dance, D. Dance, S. Rattanavong, V. Davong, L. Q. Hung, N. Chau, N. L. Tung, A. Chan, A. Chan, G. Thwaites, D. G. Lalloo, C. Anscombe, L. Nhat, J. Perfect, G. Dougan, G. Dougan, G. Dougan, S. Baker, S. R. Harris, J. N. Day   +29 more
semanticscholar   +1 more source

Capsules from pathogenic and non-pathogenic Cryptococcus spp. manifest significant differences in structure and ability to protect against phagocytic cells. [PDF]

PLoS ONE, 2012
Capsule production is common among bacterial species, but relatively rare in eukaryotic microorganisms. Members of the fungal Cryptococcus genus are known to produce capsules, which are major determinants of virulence in the highly pathogenic species ...
Glauber de S Araujo, Fernanda L Fonseca, Bruno Pontes, Andre Torres, Radames J B Cordero, Rosely M Zancopé-Oliveira, Arturo Casadevall, Nathan B Viana, Leonardo Nimrichter, Marcio L Rodrigues, Eloi S Garcia, Wanderley de Souza, Susana Frases   +12 more
doaj   +1 more source

Thermotolerance in the pathogen Cryptococcus neoformans is linked to antigen masking via mRNA decay-dependent reprogramming

Nature Communications, 2019
A common feature shared by systemic fungal pathogens of environmental origin, such as Cryptococcus neoformans, is their ability to adapt to mammalian core body temperature. In C.
Amanda L. M. Bloom, Richard M. Jin, Jay Leipheimer, J. Bard, D. Yergeau, E. Wohlfert, J. Panepinto   +6 more
semanticscholar   +1 more source

Identification of Pathogen Genomic Differences That Impact Human Immune Response and Disease during Cryptococcus neoformans Infection

mBio, 2019
Even with the best available care, mortality rates in cryptococcal meningitis range from 20% to 60%. Disease is often due to infection by the fungus Cryptococcus neoformans and involves a complex interaction between the human host and the fungal pathogen.
A. Gerstein, Katrina M Jackson, Tami R. McDonald, Yina Wang, Benjamin D. Lueck, S. Bohjanen, Kyle Smith, A. Akampurira, D. Meya, C. Xue, D. Boulware, Kirsten Nielsen   +11 more
semanticscholar   +1 more source

Cryptococcus neoformans Cda1 and Its Chitin Deacetylase Activity Are Required for Fungal Pathogenesis

mBio, 2018
Cryptococcus neoformans is unique among fungal pathogens that cause disease in a mammalian host, as it secretes a polysaccharide capsule that hinders recognition by the host to facilitate its survival and proliferation.
R. Upadhya, L. G. Baker, Woei C. Lam, C. Specht, M. Donlin, J. Lodge   +5 more
semanticscholar   +1 more source

Mechanisms of Cryptococcus neoformans-Mediated Host Damage

Frontiers in Immunology, 2018
Cryptococcus neoformans is not usually considered a cytotoxic fungal pathogen but there is considerable evidence that this microbe can damage host cells and tissues. In this essay, we review the evidence that C.
A. Casadevall, C. Coelho, A. Alanio
semanticscholar   +1 more source

Canavanine resistance in Cryptococcus neoformans [PDF]

Antimicrobial Agents and Chemotherapy, 1986
All of the isolates of Cryptococcus neoformans var. gattii which we tested were resistant to greater than or equal to 3.5 mM canavanine. All of the serotype D isolates and 28% of the serotype A isolates of C. neoformans var. neoformans tested were susceptible to less than or equal to 18 microM canavanine, whereas the remaining 72% of the serotype A ...
K J Kwon-Chung, I Polacheck
openaire   +2 more sources

Cerebrospinal Fluid Metabolome in Central Nervous System Infections: A Study of Diagnostic Accuracy

Annals of Neurology, EarlyView.
Objective To assess the diagnostic accuracy of metabolites in cerebrospinal fluid (CSF) for central nervous system (CNS) infections. Methods Patients were derived from three prospective cohort studies in the Netherlands. All studies included adults suspected of a CNS infection who underwent a diagnostic lumbar puncture.
Steven L. Staal, Sabine E. Olie, Michel van Weeghel, Bauke V. Schomakers, Frédéric M. Vaz, I‐PACE Study Group, Diederik van de Beek, Matthijs C. Brouwer   +7 more
wiley   +1 more source

Suscetibilidade a antifúngicos de variedades de Cryptococcus neoformans isoladas de pacientes em hospital universitário Susceptibility to antifungal agents among Cryptococcus neoformans varieties isolated from patients at a university hospital

Revista da Sociedade Brasileira de Medicina Tropical, 2008
Este trabalho identificou variedades de Cryptococcus neoformans e avaliou a suscetibilidade a antifúngicos pelo protocolo M27-A2 do National Committee for Clinical Laboratory Standards em isolados de 35 pacientes do Hospital Escola da Universidade ...
Paulo Roberto da Silva, Rosiley Aparecida de Souza Rabelo, Ana Paula Sarreta Terra, David Nascimento Silva Teixeira   +3 more
doaj   +1 more source