Results 71 to 80 of about 9,604 (179)

Unveiling the Silent Regulators: Noncoding RNAs in Parasitic Disease Diagnosis and Therapy

Journal of Parasitology Research, Volume 2026, Issue 1, 2026.
Parasitic diseases remain a major global health burden, particularly in tropical and low‐resource regions, where limitations in early diagnosis and effective therapeutics contribute to high morbidity and mortality. Emerging evidence highlights noncoding RNAs (ncRNAs) as critical regulators of host–parasite interactions, offering novel opportunities for
Neyon Loku Gamage, Koshila Ranasinghe, Satabdi Datta Choudhury   +2 more
wiley   +1 more source

MicroRNA expression profile of HCT-8 cells in the early phase of Cryptosporidium parvum infection

BMC Genomics, 2019
Background Cryptosporidium parvum is an important zoonotic parasitic disease worldwide, but the molecular mechanisms of the host–parasite interaction are not fully understood.
Chenrong Wang, Limin Liu, Huili Zhu, Lu Zhang, Rongjun Wang, Zhenjie Zhang, Jianying Huang, Sumei Zhang, Fuchun Jian, Changshen Ning, Longxian Zhang   +10 more
doaj   +1 more source

Molecular characterization and zoonotic risk assessment of Cryptosporidium spp. in children and calves in Bangladesh

One Health
Cryptosporidium is a gastro-intestinal protozoan parasite that has been found to infect both humans and livestock. This study investigated the parasite in 998 fecal samples from Bangladeshi children (n = 299) and calves (n = 699) to determine its ...
Md Robiul Karim, Junqiang Li, Anas Bin Harun, Farzana Islam Rume, Longxian Zhang   +4 more
doaj   +1 more source

Disposable microfluidic micromixers for effective capture of Cryptosporidium parvum oocysts from water samples

Journal of Biological Engineering, 2018
Background Protecting drinking water supplies from pathogens such as Cryptosporidium parvum is a major concern for water utilities worldwide. The sensitivity and specificity of current detection methods are largely determined by the effectiveness of the ...
L. Diéguez, M. Winter, S. Molan, P. Monis, B. King, B. Thierry   +5 more
doaj   +1 more source

Differential evolution of repetitive sequences in Cryptosporidium parvum and Cryptosporidium hominis

Infection, Genetics and Evolution, 2006
Cryptosporidium parvum and Cryptosporidium hominis are two morphologically identical species of Apicomplexan protozoa infecting humans. Although the genomes of these species are 97% identical, their host range is strikingly different. C. parvum infects humans and animals and is primarily a zoonotic infection, whereas C.
Sultan, Tanriverdi, Giovanni, Widmer
openaire   +2 more sources

Novel lactate dehydrogenase inhibitors with in vivo efficacy against Cryptosporidium parvum.

PLoS Pathogens, 2019
Cryptosporidium parvum is a highly prevalent zoonotic and anthroponotic protozoan parasite that causes a diarrheal syndrome in children and neonatal livestock, culminating in growth retardation and mortalities. Despite the high prevalence of C.
Kun Li, Sara M Nader, Xuejin Zhang, Benjamin C Ray, Chi Yong Kim, Aditi Das, William H Witola   +6 more
doaj   +1 more source

Molecular identification and genetic diversity analysis of Cryptosporidium spp. infecting dogs from central and northern Jordan: Detection of zoonotic genotype IId.

PLoS ONE
Cryptosporidium spp. are common causes of gastrointestinal disease in both humans and animals. This was a cross-sectional study conducted to determine the infection rate and genetic characteristics of Cryptosporidium infecting dogs in Jordan.
Rami M Mukbel, Eman M Etoom, Haifa B Hammad, Heidi L Enemark, Marwan M Abu Halaweh   +4 more
doaj   +1 more source

LncRNA BACE1-AS delays the propagation of Cryptosporidium parvum through regulating cell apoptosis by targeting the miR-6805-5p/IRF3 axis

Microbiology Spectrum
Cryptosporidium spp. are important zoonotic pathogens causing diarrhea in humans and various animals. To date, there are still no effective drugs and vaccines for the prevention and treatment of cryptosporidiosis, mainly due to the absence of knowledge ...
Shuang Huang, Xin Yang, Ting-Li Liu, Gui-Rong Hu, Qian Yao, Jun-Ke Song, Ying-Ying Fan, Guang-Hui Zhao   +7 more
doaj   +1 more source

Molecular characterization of Cryptosporidium spp. in goats (Capra hircus) from Zhejiang Province, China: evidence of zoonotic species and subtypes

BMC Microbiology
Background Cryptosporidium spp. are protozoan pathogens that infect the gastrointestinal tracts of humans and animals, posing significant zoonotic risks. Goats are recognized as important hosts; however, their role in the epidemiology and transmission of
Xinyu Hu, Lijie Sun, Yuman Li, Fang Shi, He Yan, Haowen Dong, Aiying Jiang, Baolong Yan, Huicong Huang, Yanyan Jiang, Wei Zhao   +10 more
doaj   +1 more source

A Multi-Locus Study of Cryptosporidium Parasites Isolated From Patients Living In Iran, Malawi, Nigeria, the United Kingdom, and Vietnam

Iranian Journal of Parasitology, 2014
Background: Cryptosporidium species are important cause of diarrheal diseases in both developing and developed countries. This study aimed to compare the perfor-mance of several molecular methods for identification of Cryptosporidium species, and to ...
Salman Ghaffari, Narges Kalantari
doaj