Results 101 to 110 of about 5,245 (194)
Free Radicals in Health and Disease
MedComm, Volume 6, Issue 10, October 2025.Free radicals have dual roles that can either selectively create oxidative damages to transformed cells in treating proliferative diseases such as cancers and some dermatological disorders or boost the antioxidant system in treating degenerative diseases such as neurodegenerative disorder, joint degeneration, and metabolic conditions.
Xiaofeng Dai, Zizheng Huang, Ruohan Lyu
wiley +1 more source
Ethosomes Loaded with Cryptotanshinone for Acne Treatment through Topical Gel Formulation
PLOS ONE, 2016 The aim of this study was to develop ethosomes loaded with cryptotanshinone (CPT) and formulate them as a topical gel for the treatment of acne. Ethosomes were prepared and evaluated for vesicle size, CPT loading and encapsulation efficiency. Optimized ethosomes were formulated as Carbomer 974 gels and compared with conventional hydroethanolic gels for
Zhenwei Yu, Hongyan Lv, Gang Han, Ke Ma
openaire +4 more sources
Thoracic Cancer, Volume 16, Issue 19, October 2025.Radiation‐induced lung injury (RILI) is a common complication of thoracic radiotherapy, and Qingdi mixture (QDM) has shown efficacy in its prevention. Through network pharmacology, molecular docking, and experimental validation, QDM was found to mitigate RILI primarily by inhibiting the NF‐κB signaling pathway and reducing inflammatory cytokines ...
Haoran Liu +8 more
wiley +1 more source
Towards targeting overactive BMP signaling in Fibrodysplasia Ossificans Progressiva [PDF]
, 2015 Fibrodysplasia Ossificans Progressiva (FOP) is a rare monogenetic disorder in which patients develop heterotopic ossification (HO). A heterozygous mutation in BMP type I receptor ALK2 results in hyper-sensitized BMP signaling. The aim of this study is to
Sánchez-Duffhues, Gonzalo +2 more
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Herbal Medicine for Colorectal Cancer Treatment: Molecular Mechanisms and Clinical Applications
Cell Proliferation, Volume 58, Issue 10, October 2025.Colorectal cancer is a prevalent gastrointestinal tumour and the second deadliest cancer worldwide, affecting approximately 10% of all cancers and cancer‐related deaths. Current clinical methods for treating CRC cause gastrointestinal abnormalities and myelosuppression.
Zuqing Su +5 more
wiley +1 more source
A review study on medicinal plants affecting amnesia through cholinergic system [PDF]
, 2012 Neurotransmitter modification is an important method for the treatment of memory loss or amnesia. Cholinomimetic drugs, particularly, acetylcholine esterase inhibitors are the mainstream in pharmacotherapy of amnesia. Donepezil, tacrine, galantamine, and
Baradaran, Azar. +3 more
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Chromium Enhances Insulin Responsiveness via AMPK [PDF]
, 2014 Trivalent chromium (Cr3+) is known to improve glucose homeostasis. Cr3+ has been shown to improve plasma membrane-based aspects of glucose transporter GLUT4 regulation and increase activity of the cellular energy sensor 5′ AMP-activated protein kinase ...
Elmendorf, Jeffrey S. +5 more
core +1 more source
Plant Biotechnology Journal, Volume 23, Issue 10, Page 4367-4380, October 2025.Summary Plants produce a variety of secondary metabolites, and their biosynthesis is often regulated by multiple transcription factors. However, the potential connections between the biosynthesis of different types of metabolites remain unclear. In this study, we present a novel mechanism in which the MYB39‐MYB111‐bHLH51‐TTG1 module synergistically ...
Bingcong Xing +13 more
wiley +1 more source
인간 구강암 세포주에서 STAT3–Mcl-1 신호기전을 표적하는 TW-37의 세포자멸 및 상승 작용에 관한 연구 [PDF]
, 2021 학위논문(박사) -- 서울대학교대학원 : 치과대학 치의과학과, 2021.8. 조성대.Background: Despite being one of the leading cancer types in the world, the diagnosis of oral cancer and its suitable therapeutic options remain limited.
홍승현
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Cytochrome P450 enzyme mediated herbal drug interactions (Part 2) [PDF]
, 2014 To date, a number of significant herbal drug interactions have their origins in the alteration of cytochrome P450 (CYP) activity by various phytochemicals. Among the most noteworthy are those involving St.
Phopin, Kamonrat +2 more
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