Results 81 to 90 of about 5,245 (194)

Preparation and Enhanced Oral Bioavailability of Cryptotanshinone-Loaded Solid Lipid Nanoparticles [PDF]

AAPS PharmSciTech, 2010
In this study, solid lipid nanoparticles (SLNs) were successfully prepared by an ultrasonic and high-pressure homogenization method to improve the oral bioavailability of the poorly water-soluble drug cryptotanshinone (CTS). The particle size and distribution, drug loading capacity, drug entrapment efficiency, zeta potential, and long-term physical ...
LianDong, Hu, Qianbin, Xing, Jian, Meng, Chuang, Shang   +3 more
openaire   +2 more sources

Research Progress on Salvia miltiorrhiza Bioactive Components Regulating P‐Selectin for Microcirculatory Improvement: Potential Implications in Acute Pancreatitis

Mediators of Inflammation, Volume 2026, Issue 1, 2026.
Severe acute pancreatitis (SAP) is associated with high morbidity and mortality. Microcirculatory dysfunction is a critical pathological event in this process and a primary contributor to organ failure (OF). Despite the pivotal role of P‐selectin in mediating the adhesion of activated platelets and leukocytes to the vascular endothelium, a process ...
Yali Liu, Xinyi Ao, Weian Hao, Honglian Wang, Li Li, Shuang Wang, Jinyi Li, Jianqin Liu, Xin Zhou, Zhi Li, Zoltan Rakonczay Jr.   +10 more
wiley   +1 more source

eIF4A/PDCD4 Pathway, a Factor for Doxorubicin Chemoresistance in a Triple-Negative Breast Cancer Cell Model

Cells, 2022
Cells employ several adaptive mechanisms under conditions of accelerated cell division, such as the unfolded protein response (UPR). The UPR is composed of a tripartite signaling system that involves ATF6, PERK, and IRE1, which maintain protein ...
Alina González-Ortiz, Angel Pulido-Capiz, César Y. Castañeda-Sánchez, Esmeralda Ibarra-López, Octavio Galindo-Hernández, Maritza Anahí Calderón-Fernández, Leslie Y. López-Cossio, Raul Díaz-Molina, Brenda Chimal-Vega, Nicolás Serafín-Higuera, Iván Córdova-Guerrero, Victor García-González   +11 more
doaj   +1 more source

Biopiracy versus one-world medicine – from colonial relicts to global collaborative concepts [PDF]

, 2019
Background: Practices of biopiracy to use genetic resources and indigenous knowledge by Western companies without benefit-sharing of those, who generated the traditional knowledge, can be understood as form of neocolonialism.Hypothesis: : The One-World ...
Abdelfatah, Sara, Abu-Darwish, Mohammad Sanad, Banerjee, Mita, Bhakta-Guha, Dipita, Bockers, Madeleine, Bolzani, Vanderlan, Daak, Salah, Dawood, Mona, Demirezer, Omur Lutfiye, Efferth, Monika, Efferth, Thomas, El-Seedi, Hesham R., Fischer, Nicolas, Greten, Henry J., Hamdoun, Sami, Hong, Chunlan, Horneber, Markus, Kadioglu, Onat, Khalid, Hassan E., Khalid, Sami A., Kuete, Victor, Mahmoud, Nuha, Marin, José, Mbaveng, Armelle, Midiwo, Jacob, Nakagawa, Hiroshi, Naß, Janine, Ngassapa, Olipa, Ochwang, Dominic, Omosa, Leonida K., Ooko, Edna A., Paramasivan, Poornima, Paul, Norbert W., Rodriguez Romero, Marta, Saeed, Elfatih M., Saeed, Mohamed E.M., Salgueiro, Ligia, Seo, Ean-Jeong, Yan, Ge, Yasin, Zahir, Özenver, Nadire   +40 more
core   +2 more sources

Expression of P53 and Bcl2 Mammary Adenocarcinoma in C3H Mice Administered with Salvia Miltiorrhizae Bunge Root Extract [PDF]

, 2016
BackgroundBreast cancer is on the first or second most Malignancy in many places around the world. The incidence of breast cancer was increasing, also in Indonesia.
Dewi, L. S. (Liza), Widjayahadi, N. (Noor), Wijaya, I. (Indra)   +2 more
core   +3 more sources

Cryptotanshinone induces ROS-mediated apoptosis in human gastric cancer cells

Oncotarget, 2017
Cryptotanshinone (CT), isolated from the plant Salvia miltiorrhiza Bunge, has been reported to have potential anticancer effects on human prostate and breast cancer cells. However, the mechanisms of action of CT on gastric cancer (GC) cells are not well understood.
Liu, Chang, Sun, Hu-Nan, Luo, Ying-Hua, Piao, Xian-Ji, Wu, Dan-Dan, Meng, Ling-Qi, Wang, Yue, Zhang, Yi, Wang, Jia-Ru, Wang, Hao, Xu, Wan-Ting, Li, Jin-Qian, Liu, Yang, Wu, Yi-Qin, Han, Ying-Hao, Shen, Gui-Nan, Jin, Mei-Hua, Zang, Yan-Qing, Li, Jing-Chun, Fang, Nan-Zhu, Cui, Yu-Dong, Jin, Cheng-Hao   +21 more
openaire   +2 more sources

Cryptotanshinone Attenuated Pathological Cardiac Remodeling In Vivo and In Vitro Experiments

Oxidative Medicine and Cellular Longevity, 2023
Objective. Cardiac remodeling has been demonstrated to be the early stage and common pathway for various types of cardiomyopathy, but no specific treatment has been suggested to prevent its development and progress. This study was aimed at assessing whether Cryptotanshinone (CTS) treatment could effectively attenuate cardiac remodeling in vivo and in ...
Wen-jing Li, Han Yan, Zi-ying Zhou, Nan Zhang, Wen Ding, Hai-han Liao, Qi-zhu Tang   +6 more
openaire   +2 more sources

Metabolism of Tanshinone IIA, Cryptotanshinone and Tanshinone I from Radix Salvia Miltiorrhiza in Zebrafish

Molecules, 2012
The study aimed to investigate the potential of zebrafish in imitating mammal phase I metabolism of natural compounds. Three diterpenoid quinones from Radix Salvia miltiorrhiza, namely tanshinone IIA (TIIA), cryptotanshinone (Cry) and tanshinone I (TI ...
Bing Wang, Xiaobin Jia, Luan Shu, Yunru Peng, Changmei Wang, Ping Li, Yingjie Wei, Wenquan Ma   +7 more
doaj   +1 more source

Countercurrent chromatography in analytical chemistry (IUPAC technical report) [PDF]

, 2009
© 2009 IUPACCountercurrent chromatography (CCC) is a generic term covering all forms of liquid-liquid chromatography that use a support-free liquid stationary phase held in place by a simple centrifugal or complex centrifugal force field. Biphasic liquid
Abbey, Abe, Abe, Abe, Akiba, Akiba, Akiba, Alain Berthod, Bauer, Bauer, Berthod, Berthod, Berthod, Berthod, Berthod, Berthod, Billardello, Boris Spivakov, Chen, Chen, Chen, Chen, Chmutova, Chmutova, Chmutova, Conway, Conway, Conway, Countercurrent Chromatography, Dekker, Fedotov, Fitz, Friesen, Fujita, Garcia Dominguez, Hashimoto, Hashimoto, Ian A. Sutherland, Ikai, Ito, Ito, Ito, Ito, Ito, Jin, Jin, Jin, Kawamura, Kawamura, Kidwell, Kitazume, Kitazume, Kitazume, Kitazume, Kitazume, Kong, Lee, Lee, Lee, Lee, Liu, Ma, Ma, Mandava, Mandava, Marston, Marston, Marston, Maryutina, Maryutina, Maryutina, Maryutina, Maryutina, Matsuda, Menet, Muralidharan, Nakamura, Nakamura, Oleg Shpigun, Pauli, Pukhovskaya, Ruiz, Ruiz, Ruth, Schaufelberger, Schaufelberger, Schreiber, Shang, Spivakov, Spivakov, Spivakov, Stark, Sutherland, Tanaka, Tatyana Maryutina, Thurman, Tian, Usuda, Usuda, Wang, Wang, Watkins, Winterhalter, Wood, Wu, Yanagida, Yang, Yang, Yang, Yoshida, Yu, Zhang, Zhang   +112 more
core   +2 more sources

Enhancing Metabolic Engineering in Medicinal Plants Through Prime Editing

Plant Biotechnology Journal, EarlyView.
Haomiao Yu, Xiao Feng, Xiaohang Zheng, Xiao Wang, Wenxin Zheng, Zhizhou Zhang, Yuanyuan Jiang, Ruiwu Yang, Li Zhang, Zhaohui Zhong   +9 more
wiley   +1 more source