Results 91 to 100 of about 6,833,641 (305)
A top–down approach to crystal engineering of a racemic Δ2-isoxazoline
, 2014 The crystal structure of racemic dimethyl (4RS, 5RS)-3-(4-nitrophenyl)-4,5-dihydroisoxazole-4,5-dicarboxylate, C13H12N2O7, has been determined by single-crystal X-ray diffraction. By analysing the degree of growth of the morphologically important crystal
Giuseppe M. Lombardo +9 more
core +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Engineering of recombinant crystallization chaperones [PDF]
Current Opinion in Structural Biology, 2009 The preparation of diffraction quality crystals remains the major bottleneck in macromolecular X-ray crystallography. A crystallization chaperone is an auxiliary protein, such as fragments of monoclonal antibodies, that binds to and increases the crystallization probability of a target molecule of interest.
openaire +2 more sources
FEBS Open Bio, EarlyView.KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph +7 more
wiley +1 more source
Crystal structure of 4-(4-(1H-imidazol-1-yl)phenyl)-2,6-diphenylpyridine, C26H19N3
Zeitschrift für Kristallographie - New Crystal Structures, 2005 C26H19N3, monoclinic, P121/c1 (no. 14), a = 12.885(1) Å, b = 15.007(2) Å, c = 10.863(2) Å, β = 109.460(8)°, V = 1980.4 Å3, Z = 4, Rgt(F) = 0.060, wRref(F2) = 0.184, T = 293 K.
Wu Y.-Z. +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli +3 more
wiley +1 more source
Crystal engineering - retrospect and prospect
, 2003 School of Chemistry, University of Hyderabad, Hyderabad-500 046, India E-mail: desiraju@uuhyd.ernet.in Crystal engineering - retrospect and ...
Gautam R. Desiraju
core +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
Recent advances in crystal engineering
, 2009 The articles published in the tenth anniversary issue of CrystEngComm are reviewed. The issue highlighted the state-of-the-art of crystal engineering and new trends and developing areas in crystal engineering.
Champness, Neil R. +7 more
core +1 more source
ElectronTwo‐dimensional (2D) gallium oxide (Ga2O3) holds great promise for photocatalysis due to its intrinsic out‐of‐plane polarization and built‐in electric field, which facilitate charge separation.
Qi Li +10 more
doaj +1 more source