Results 91 to 100 of about 285,778 (313)

A reverse crystal Engineering approach

open access: yes, 2013
The enormous impact of crystal engineering in modern solid state chemistry takes advantage from the connection between a typical basic science field and the word engineering.
Macchi, Piero
core  

Numerical Analysis of Phosphorus Concentration Distribution in a Silicon Crystal during Directional Solidification Process

open access: yes, 2020
For bulk doping, boron and phosphorus are usually used as p-type and n-type dopants, respectively. The distribution of these dopant concentrations in a silicon crystal along the vertical direction is governed by the segregation phenomena.
Satoshi Nakano   +3 more
core   +1 more source

Abnormal lattice occupation of Mo and related polarons in LiNbO3: Hybrid density functional theory investigation

open access: yesJournal of Materiomics, 2020
Studies have reported that Mo-doped LiNbO3 exhibits excellent photorefractive performance, which may be attributed to the Mo abnormally occupation in Nb sites (MoNb) and the MoNb photorefractive centres.
Lili Li   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Materials and Structural Engineering

open access: yes, 2014
Presented as part of the "Great Buildings & Structures that Made a Difference: The Crystal Palace, London, 1851" Symposium on September 3, 2014 in the Reinsch-Pierce Auditorium in the College of Architecture from 4:30 pm - 8:00 pm.Runtime: 22:53 ...
Kahn, Lawrence F.
core  

Reversible conductivity modulation by tuning surface band bending in Sn-doped β-Ga2O3 single crystal

open access: yesAPL Materials
Developing methods for modulating the band structure of semiconductor material is crucial for the application. In this work, the electron concentration of heavy Sn doped β-Ga2O3 crystals showed an interesting partially reversible phenomenon after ...
Yiyuan Liu   +6 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Dynamic Simulation of the Temperature Field of LiH Single Crystal Growth

open access: yes, 2023
The single-crystal lithium hydride (LiH) generally grows in a gradient temperature region with the Bridgman method. A stable and appropriate temperature gradient is crucial in the crystallization process.
Jipeng Zhu   +7 more
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

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