Results 71 to 80 of about 6,833,641 (305)

Crystal Engineering in Continuous Plug-Flow Crystallizers [PDF]

Crystal Growth & Design, 2017
Abstract Size, shape, and polymorphic form are the critical attributes of crystalline particles and represent the major focus of today’s crystallization process design. This work demonstrates how crystal properties can be tuned efficiently in solution via a tubular crystallizer that facilitates rapid temperature cycling.
Maximilian O. Besenhard, Peter Neugebauer, Otto Scheibelhofer, Johannes G. Khinast   +3 more
openaire   +3 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Halogen bond mediated crystal engineering of metal complexes [PDF]

, 2014
This project explored the potential for halogen bonds to predictably organise metal-containing molecular building blocks in crystalline materials. A novel method for the halogen bond mediated crystal engineering of metal complexes was discovered, which ...
Pfrunder, Michael Craig
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Induced fit growth of Ga-based semiconductor thin films for brain-inspired electronics and optoelectronics

Light: Science & Applications
Current crystalline thin-film production techniques typically require specific growth substrates, posing significant challenges for their use in flexible electronics and integrated optoelectronics.
Zixu Sa, Kepeng Song, You Meng, Wenfeng Wu, Zhaocong Wang, Pengsheng Li, Jie Zhang, Zeqi Zang, Guangcan Wang, Mingxu Wang, Zhitai Jia, Yang Tan, Weifeng Li, SenPo Yip, Feng Chen, Johnny C. Ho, Zai-xing Yang   +16 more
doaj   +1 more source

Ultrahigh-temperature piezoelectric crystal ErxGd1−xCa4O(BO3)3 with near-zero temperature-shift of piezoelectric properties

Journal of Materiomics
To meet the sensing demands of extreme environments, such as those encountered in aircraft engines and nuclear industries, there is an urgent need to develop new piezoelectric crystals with excellent stability in piezoelectric performance. In this study,
Zijian Liu, Xiaojuan Wang, Dingting Yang, Dongyang Tian, Xueliang Liu, Yanlu Li, Xiulan Duan, Xian Zhao, Fapeng Yu   +8 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Author Correction: Liquid crystal elastomer coatings with programmed response of surface profile

Nature Communications, 2018
The original version of this Article contained errors in Figs. 1a, 2a, 3a, and 4b, in which the units on the scale bars incorrectly read ‘µm’ rather than the correct ‘nm.’ This has been corrected in both the PDF and HTML versions of the Article.
Greta Babakhanova, Taras Turiv, Yubing Guo, Matthew Hendrikx, Qi-Huo Wei, Albert P. H. J. Schenning, Dirk J. Broer, Oleg D. Lavrentovich   +7 more
doaj   +1 more source

Controlled Synthesis and Properties of 3d–4f Metals Co-doped Polyoxometalates-Based Materials

Nanoscale Research Letters, 2020
It is challenging to explore and prepare polyoxometalates-based nanomaterials (PNMs) with controllable morphologies and diversiform components. Herein, 3d–4f metals are introduced into isopolyoxometalates and Anderson-type polyoxometalates, CeCdW12 ...
Ning Liu, Ningning Guo, Lin Sun, Shixian Liu, Guan Wang, Yuan Zhao   +5 more
doaj   +1 more source