Results 61 to 70 of about 285,778 (313)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Liquid crystal elastomer coatings with programmed response of surface profile

open access: yesNature Communications, 2018
Liquid crystal elastomers are anisotropic rubbers which can be actuated by an external trigger. Here the authors develop elastomer coatings with pre-patterned molecular orientation that induces deterministic topography changes in response to changes in ...
Greta Babakhanova   +7 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Mechanism Design with Singularity Avoidance of Crystal-Inspired Deployable Structures

open access: yes, 2019
Although deployable structures have important applications in various fields, developing a new form of structural configuration faces some scientific challenges.
Jian Feng, Yao Chen, Jiayi Yan
core   +1 more source

Pyroelectric Properties of Bismuth Borate BZBO Single Crystals

open access: yesCrystals, 2021
Pyroelectric properties of orthorhombic Bi2ZnB2O7 (BZBO) crystals were investigated by using the charge integration method. The primary and the secondary pyroelectric coefficients of BZBO crystals were found to be 6.4 and −6.5 µC/(m2·°C), respectively ...
Feifei Chen   +3 more
doaj   +1 more source

Chemical crystallography and crystal engineering [PDF]

open access: yesIUCrJ, 2014
Today, there is very little doubt that chemistry owes as much to crystallography as crystallography does to chemistry. This mutual synergy defines modern chemical crystallography.
openaire   +4 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Organic Crystal Engineering: Frontiers in Crystal Engineering

open access: yes, 2010
10.1002/9780470681794Organic Crystal Engineering: Frontiers in Crystal ...
Vittal, J.   +2 more
core   +1 more source

Photon Confinement in Photonic Crystal Cavities [PDF]

open access: yes, 2010
In this thesis, the use of photonic crystal cavities for experiments in cavity quantum-electrodynamics is described. To this end, the propagation of light in photonic crystals, and the creation of cavities by making defects in the photonic crystal ...
Khankhoje, Uday Kiran
core   +1 more source

Artificial Neural Network for the Prediction of Fatigue Life of Microscale Single-Crystal Copper

open access: yes, 2023
Microscale single-crystal copper is widely used in electronics, communications and other fields due to its excellent properties such as high ductility, high toughness and good conductivity.
Fanming Zeng, Yabin Yan
core   +1 more source

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