Results 51 to 60 of about 6,833,641 (305)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
, 2020 International audienceAs the requirements in terms of crystal defect/quality and production yield are generally contradictory, it is necessary to develop methods in order to find the best compromise for the growth conditions of a given crystal.
Duffar, Thierry, Thierry Duffar
core +1 more source
Advanced ScienceChirality and polarity are the two most important and representative symmetry‐dependent properties. For polar structures, all the twofold axes perpendicular to the principal axis of symmetry should be removed.
Shaoxin Cui +7 more
doaj +1 more source
Dendrite engineering on xenon crystals [PDF]
Physical Review E, 2007 The experimental work presented focuses on transient growth, morphological transitions, and control of xenon dendrites. Dendritic free growth is perturbed by two different mechanisms: Shaking and heating up to the melting temperature. Spontaneous and metastable multitip configurations are stabilized, coarsening is reduced, leading to a denser ...
Fell M, Bilgram J
openaire +3 more sources
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Crystals, 2020 The angular non-critical phase-matching (A-NCPM) second-harmonic-generation (SHG) properties of RE1xRE21−xCOB (RE1, RE2 = Y, Gd, La, Tm, Sm, and Nd) type mixed crystals including NCPM wavelength and conversion efficiency were detailedly investigated ...
Ranran Li +7 more
doaj +1 more source
Ultrahigh‐Temperature Piezoelectric Crystal YbBa3(PO4)3 for Vibration Sensing Application
Advanced Sensor Research, 2023 High‐temperature vibration sensors are of great importance for accurate monitoring of dynamic mechanical conditions in automotive, aerospace and energy‐generation‐related systems.
Guangda Wu +7 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Materials and Structural Engineering
, 2014 Presented as part of the "Great Buildings & Structures that Made a Difference: The Crystal Palace, London, 1851" Symposium on September 3, 2014 in the Reinsch-Pierce Auditorium in the College of Architecture from 4:30 pm - 8:00 pm.Runtime: 22:53 ...
Kahn, Lawrence F.
core +1 more source