Results 111 to 120 of about 12,346,493 (344)

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Growth and Characterization of Fe0.95Se0.6Te0.4 Single Crystal

, 2019
In this paper we present the single crystal growth of Fe0.95Se0.6Te0.4 high TC superconducting sample by the modified Bridgman technique. The x-ray diffraction pattern shows the single crystal nature of the sample, as only (00l) peaks are detectable. The
Dhaka, Rajendra S., Maurya, Vishal K., Shukla, Anmol   +2 more
core   +1 more source

Seeded growth of single-crystal two-dimensional covalent organic frameworks

Science, 2018
Covalent organic frameworks writ large Covalent organic framework (COF) materials have been difficult to characterize structurally and to exploit because they tend to form powders or amorphous materials. Ma et al.
Austin M. Evans, L. Parent, Nathan C. Flanders, Ryan P. Bisbey, Edon Vitaku, Matthew S. Kirschner, R. Schaller, Lin X. Chen, N. Gianneschi, William R. Dichtel   +9 more
semanticscholar   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Technical note: formation of airborne ice crystals in a wall independent reactor (WIR) under atmospheric conditions [PDF]

, 2008
Both, gas and particle scavenging contribute to the transport of organic compounds by ice crystals in the troposphere. To simulate these processes an experimental setup was developed to form airborne ice crystals under atmospheric conditions. Experiments
Fries, Elke, Haunold, Werner, Jaeschke, Wolfgang, Palitzsch, Katrin, Püttmann, Wilhelm (Prof. Dr.), Sitals, Robert, Starokozhev, Elena   +6 more
core  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Comparative Performance of Tetraphosphonate and Diphosphonate as Reverse Osmosis Scale Inhibitors

MATEC Web of Conferences, 2018
Reverse osmosis (RO) technologies are widely used throughout the world for drinking, industrial and waste water treatment purposes. Proper and economically attractive operation of RO installations should be provided by the correct maintenance of all ...
Andrianov Alexey, Danilycheva Maria, Liakaki-Stavropoulou Stefania, Demadis Konstantinos D., Efremov Roman   +4 more
doaj   +1 more source

Identification of the transition rule in a modified cellular automata model: the case of dendritic NH4Br crystal growth [PDF]

, 2008
A method of identifying the transition rule, encapsulated in a modified cellular automata (CA) model, is demonstrated using experimentally observed evolution of dendritic crystal growth patterns in NH4Br crystals.
Billings, S.A., Coca, D., DeMatos, L., Ristic, R.I., Zhao, Y.   +4 more
core  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source