Dimerization of natively folded molecules drives misfolding and aggregation in Cys-depleted variants of cataract-associated human lens γD-crystallin. [PDF]
J Biol ChemPu Y +4 more
europepmc +1 more source
The Mammalian Ocular Lens in Focus: Development, Anatomy, Physiology, Transparency, Biomechanics, and Age-related Challenges. [PDF]
J Vis ExpCheng C, Vu MP.
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βA4-Crystallin Mutations Disrupt Structural Stability and Crystallin Interactions in Congenital Cataract Pathogenesis. [PDF]
Invest Ophthalmol Vis SciLin X +11 more
europepmc +1 more source
Proteomic Analysis of Retinas from Two Different Type-1 Diabetic Models. [PDF]
BiomoleculesAlahdab G +9 more
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Lipid Peroxidation Increases Lens Stiffness and Is Associated With αA-Crystallin Accumulation at the Plasma Membrane: An Ex Vivo Study. [PDF]
Invest Ophthalmol Vis SciFan E, Hao C, Zheng S, Zhang M, Fan X.
europepmc +1 more source
Tryptophan oxidation-induced dynamics highlight why stable γS-crystallin variants aggregate. [PDF]
Biophys Rep (N Y)Seo Y +7 more
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Variants and genotype-phenotype correlation of CRYBB2 gene in eight Chinese families with congenital cataract and other congenital ocular anomalies. [PDF]
BMC OphthalmolZhang H +7 more
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The Structural Order of Crystallin Proteins During Early Human Lens Development. [PDF]
Invest Ophthalmol Vis SciBains KK +10 more
europepmc +1 more source
Deamidation Promotes AGE-Modifications in Human Lens γS-Crystallin. [PDF]
BiochemistryPanja S, Nagaraj RH.
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