Results 111 to 120 of about 18,186 (212)

Anterior chamber flare and central macular thickness after trabeculectomy versus after phacoemulsification

open access: yesActa Ophthalmologica, Volume 104, Issue 4, Page 402-409, June 2026.
Abstract Purpose To compare the inflammatory response in the eye after trabeculectomy to after phacoemulsification, focusing on anterior chamber flare (AC flare) and central macular thickness (CMT). Methods Data from 436 participants in two randomized controlled trials were analysed.
Yasmeen Ahmed   +5 more
wiley   +1 more source

Post-Translational Modification of Crystallins in Vitreous Body from Experimental Autoimmune Uveitis of Rats

open access: yes, 2007
Experimental autoimmune uveitis (EAU) is a well-known animal model of posterior uveitis that is one of the major causes of blindness. EAU could be induced in susceptible animals (i.e., Lewis rat) by immune reactions using evolutionarily conserved retinal
Hun-Taeg Chung (583329)   +8 more
core   +3 more sources

Elucidating the mechanism of anti-apoptotic activity of α-crystallin and its therapeutic potential [PDF]

open access: yesJournal of Stress Physiology & Biochemistry
α- Crystallins are the structural proteins of the eye lens which possess anti-apoptotic activity. Both αA- and αB- crystallins are distinct antiapoptotic regulators which can interact with Bax and Bcl-XS, proapoptotic members of the Bcl-2 family in order
Aparajita Chakraborty   +2 more
doaj  

Genome‐Wide Population Structure of Lake Whitefish (Coregonus clupeaformis) in a Subarctic Great Lake

open access: yesEvolutionary Applications, Volume 19, Issue 6, June 2026.
ABSTRACT Advances in genomics have facilitated the delineation of fisheries management units, which can be challenging in systems such as large lakes, in which high gene flow tends to limit genetic structure. In Great Slave Lake, Lake Whitefish populations have supported an important commercial fishery since the mid‐1940s. The genetic structure of Lake
Philippe Hénault   +9 more
wiley   +1 more source

Mass spectrometric analysis of human lens crystallins

open access: yes, 1999
The disease cataract, a major cause of blindness worldwide, is an opacification of the lens. Post-translational modifications which disrupt the close-packing of the crystallins are likely causes of the change in refractive index and the formation of ...
Hanson, Stacy Rae-Abner
core  

Asymptomatic Versus Symptomatic Alzheimer's Disease Neuropathology: A Systematic Review of Differences Reported in Post‐Mortem Studies

open access: yesNeuropathology and Applied Neurobiology, Volume 52, Issue 3, June 2026.
Graphical summary of post‐mortem brain tissue findings that differ between symptomatic and asymptomatic AD. Current evidence suggests reduced accumulation of Aβ and p‐tau oligomers, particularly at synapses, preserved neuronal and synaptic integrity and metabolic activity and a dynamic profile of glial and immune responses in ASYMAD.
Thiago Guilherme Rêgo Barros   +6 more
wiley   +1 more source

Sequence Analysis of βA3, βB3, and βA4 Crystallins Completes the Identification of the Major Proteins in Young Human Lens*

open access: yesJournal of Biological Chemistry, 1997
A combination of Edman sequence analysis and mass spectrometry identified the major proteins of the young human lens as αA, αB, βA1, βA3, βA4, βB1, βB2, βB3, γS, γC, and γD-crystallins and mapped their positions on two-dimensional electrophoretic gels ...
K. Lampi   +6 more
semanticscholar   +1 more source

Evolutionary and functional relationships between the basic and acidic β-crystallins

open access: yes, 1988
β-Crystallins are complex oligomers composed of many related subunits. In order to understand their interactions we have built molecular models of several bovine β-crystallins, based on their sequence similarity to the well-defined γ-II crystallin ...
Slingsby, C.   +4 more
core   +1 more source

An Exploration of Human D-Crystallin Affinity for Potential Aggregation Inhibitors: A Molecular Docking Investigation

open access: yesStudia Universitatis Babes-Bolyai Chemia
Cataract, the leading cause of blindness worldwide, is characterized by the presence of a cloudy area in the eye lens resulting in a loss of transparency.
Călin G. FLOARE   +3 more
doaj   +1 more source

A potential role for endogenous proteins as sacrificial sunscreens and antioxidants in human tissues

open access: yesRedox Biology, 2015
Excessive ultraviolet radiation (UVR) exposure of the skin is associated with adverse clinical outcomes. Although both exogenous sunscreens and endogenous tissue components (including melanins and tryptophan-derived compounds) reduce UVR penetration, the
Sarah A. Hibbert   +7 more
doaj   +1 more source

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