Results 111 to 120 of about 18,186 (212)
Abstract Purpose To compare the inflammatory response in the eye after trabeculectomy to after phacoemulsification, focusing on anterior chamber flare (AC flare) and central macular thickness (CMT). Methods Data from 436 participants in two randomized controlled trials were analysed.
Yasmeen Ahmed +5 more
wiley +1 more source
Experimental autoimmune uveitis (EAU) is a well-known animal model of posterior uveitis that is one of the major causes of blindness. EAU could be induced in susceptible animals (i.e., Lewis rat) by immune reactions using evolutionarily conserved retinal
Hun-Taeg Chung (583329) +8 more
core +3 more sources
Elucidating the mechanism of anti-apoptotic activity of α-crystallin and its therapeutic potential [PDF]
α- Crystallins are the structural proteins of the eye lens which possess anti-apoptotic activity. Both αA- and αB- crystallins are distinct antiapoptotic regulators which can interact with Bax and Bcl-XS, proapoptotic members of the Bcl-2 family in order
Aparajita Chakraborty +2 more
doaj
ABSTRACT Advances in genomics have facilitated the delineation of fisheries management units, which can be challenging in systems such as large lakes, in which high gene flow tends to limit genetic structure. In Great Slave Lake, Lake Whitefish populations have supported an important commercial fishery since the mid‐1940s. The genetic structure of Lake
Philippe Hénault +9 more
wiley +1 more source
Mass spectrometric analysis of human lens crystallins
The disease cataract, a major cause of blindness worldwide, is an opacification of the lens. Post-translational modifications which disrupt the close-packing of the crystallins are likely causes of the change in refractive index and the formation of ...
Hanson, Stacy Rae-Abner
core
Graphical summary of post‐mortem brain tissue findings that differ between symptomatic and asymptomatic AD. Current evidence suggests reduced accumulation of Aβ and p‐tau oligomers, particularly at synapses, preserved neuronal and synaptic integrity and metabolic activity and a dynamic profile of glial and immune responses in ASYMAD.
Thiago Guilherme Rêgo Barros +6 more
wiley +1 more source
A combination of Edman sequence analysis and mass spectrometry identified the major proteins of the young human lens as αA, αB, βA1, βA3, βA4, βB1, βB2, βB3, γS, γC, and γD-crystallins and mapped their positions on two-dimensional electrophoretic gels ...
K. Lampi +6 more
semanticscholar +1 more source
Evolutionary and functional relationships between the basic and acidic β-crystallins
β-Crystallins are complex oligomers composed of many related subunits. In order to understand their interactions we have built molecular models of several bovine β-crystallins, based on their sequence similarity to the well-defined γ-II crystallin ...
Slingsby, C. +4 more
core +1 more source
Cataract, the leading cause of blindness worldwide, is characterized by the presence of a cloudy area in the eye lens resulting in a loss of transparency.
Călin G. FLOARE +3 more
doaj +1 more source
A potential role for endogenous proteins as sacrificial sunscreens and antioxidants in human tissues
Excessive ultraviolet radiation (UVR) exposure of the skin is associated with adverse clinical outcomes. Although both exogenous sunscreens and endogenous tissue components (including melanins and tryptophan-derived compounds) reduce UVR penetration, the
Sarah A. Hibbert +7 more
doaj +1 more source

