Results 91 to 100 of about 18,186 (212)
Calcium binding properties of beta-crystallins
, 1996 β-Crystallins, the oligomeric proteins of the eye lens, were found to bind calcium ions with low affinity, in the millimolar range. Calcium was found to induce conformational changes in the secondary and tertiary structure of β-crystallins.
Balasubramanian, D., Sharma, Yogendra
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Exploring the Universe within the Human Lens Through Raman Spectroscopy
Delhi Journal of Ophthalmology, 2017 Ever since the emergence of refined modalities of cataract surgery, the looming question has been the same - How to improve the technique, to minimize manipulation of biological components and optimize the end result? The most recent development has been,
Praveen K Malik +3 more
doaj +1 more source
Clinical Case Reports, Volume 14, Issue 6, June 2026.ABSTRACT High‐voltage craniofacial electrical injury may result in delayed cataract without optic nerve damage. Multimodal structural and functional assessment supports accurate prognostication, and when posterior segment integrity is preserved, visual recovery after cataract surgery is typically excellent and sustained.
Md Iftekher Iqbal, Fariah Osman
wiley +1 more source
Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.The graphical abstract follows a top‐to‐bottom flow: stressors → ER–mitochondria crosstalk → ophthalmic diseases. The central panel highlights three core mitochondria‐associated membrane function axes, color‐coded as follows: light yellow for Ca2+ homeostasis, light blue for mitochondrial dynamics, and light red for mitophagy.
Luyang Jiang +5 more
wiley +1 more source
Expression of wildtype and Secc mutant γ-crystallins.
, 2016 (A) P21 lenses were analyzed by western blotting with antibodies against total γ-crystallins and β-actin. The expression of γ-crystallins reduced significantly in Secc mutant lenses.
Sze Lan Tsang (370897) +7 more
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Physical Biology, 2011 Crystallins are present in the lens at extremely high concentrations in order to provide transparency and generate a high refractive power of the lens. The crystallin families prevalent in the highest density lens tissues are γ-crystallins in vertebrates
Huaying Zhao, M. Magone, P. Schuck
semanticscholar +1 more source
Aspartame Increases the Risk of Pancreatic Ductal Adenocarcinoma
eFood, Volume 7, Issue 3, June 2026.Aspartame (APM) is a widely used artificial sweetener associated with various health concerns, including potential links to diabetes, cardiovascular diseases, and an increased risk of cancer. A comprehensive approach incorporating data mining, machine learning, network toxicology, molecular docking, molecular dynamics simulations, and clinical sample ...
Jumin Xie +5 more
wiley +1 more source
Decreased heat stability and increased chaperone requirement of modified human βB1-crystallins
, 2002 Purpose: To determine how deamidation and partial loss of the N- and C-terminal extensions alter the heat stability of βB1-crystallin. Methods: Human lens βB1, a deamidated βB1, Q204E, and αA-crystallins were expressed.
Yung H Kim (20190102) +8 more
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Journal of Biophotonics, Volume 19, Issue 6, June 2026.A scanning laser ophthalmoscope, integrated with a real‐time optical coherence tomography (OCT) alignment monitor, detected flavoprotein fluorescence (FPF) signals associated with mitochondrial dysfunction in a rodent glaucoma model. Under 450‐nm excitation, experimental eyes showed spatially inhomogeneous signals that were absent under 505‐nm ...
Eun Ji Lee +5 more
wiley +1 more source