Results 81 to 90 of about 6,105 (219)

Molecular Adaptations and Sex‐Biased Regulatory Pathways in Multi‐Year Diapause of the Cabbage Beetle Colaphellus bowringi: A Duration‐Resolved Transcriptomic Analysis

Ecology and Evolution, Volume 16, Issue 11, November 2026.
This study presents the first multi‐duration, sex‐stratified transcriptomic analysis of prolonged diapause in Colaphellus bowringi, revealing that extended dormancy is maintained by coordinated metabolic suppression and sustained activation of cytoprotective pathways (e.g., glutathione metabolism, autophagy).
Lili Huang, Yan Ni, Xin Ye, Xiaona Liu, Fangsen Xue, Haimin He   +5 more
wiley   +1 more source

Structure of the crystallins [PDF]

Eye, 1999
The lens is formed from two protein superfamilies, the alpha- and beta gamma-crystallins. Representative three-dimensional structures show they both have a basic 2-beta-sheet domain fold, with the beta gamma-domain being made from two intercalating Greek keys.
C, Slingsby, N J, Clout
openaire   +2 more sources

Research Progression of Non-lens βγ-crystallins [PDF]

, 2009
In vertebrates, βγ-crystallins are mainly expressed in the lens as structural protein, a lot of non-lens βγ-crystallins were also discovered in microbes and mammals, such as Protein S and Absent in Melanoma 1, which act as microbial stress-inducible ...
Liu, Shu-bai, Qian, Jin-qiao, He, Ying-ying, Lee, Wen-hui, Zhang, Yun   +4 more
core   +1 more source

Exploring the Universe within the Human Lens Through Raman Spectroscopy

Delhi Journal of Ophthalmology, 2017
Ever since the emergence of refined modalities of cataract surgery, the looming question has been the same - How to improve the technique, to minimize manipulation of biological components and optimize the end result? The most recent development has been,
Praveen K Malik, Taru Dewan, Ayasha Nishad, Pulkit Gupta   +3 more
doaj   +1 more source

Hypoxic Human Induced Pluripotent Stem Cell‐Derived Cardiomyocytes Release Large Extracellular Vesicles That Promote a Pro‐Inflammatory Phenotype in Macrophages

Journal of Extracellular Biology, Volume 5, Issue 11, November 2026.
ABSTRACT Directly post‐infarction, myocardial tissue release signals that trigger an acute inflammatory response to clear debris and initiate cardiac repair. However, prolonged inflammation may drive adverse remodelling and heart failure in the long‐term.
Margarida Viola, Renee G. C. Maas, Judy M. Lowik, Tom A. P. Driedonks, Ernest Diez Benavente, Luuk van de Schepop, Cor S. Seinen, Christian J. B. Snijders Blok, Saskia C. A. de Jager, Pieter Vader, Joost P. G. Sluijter   +10 more
wiley   +1 more source

The percentage of secondary structure content of different αB-crystallins obtained by the CD studies.

, 2021
The percentage of secondary structure content of different αB-crystallins obtained by the CD studies.
Reza Yousefi (3125688), Boris I. Kurganov (456544), Seyed Hossein Khaleghinejad (11766961), Maryam Ghahramani (8602575), Ali Akbar Moosavi-Movahedi (313649), Mahtab Hafizi (11766955), Natalia A. Chebotareva (447484), Faezeh Moosavi-Movahedi (11766958)   +7 more
core   +1 more source

Multiple Sclerosis and Viruses: « Liaisons Dangereuses »

Reviews in Medical Virology, Volume 36, Issue 6, November 2026.
ABSTRACT Multiple sclerosis (MS) is a complex, multifactorial neurodegenerative disease with an aetiology that is still partially elusive. Several risk factors are associated with MS development including genetic predisposition and various environmental stressors; however, recently, viral infections have gained significant attention as a crucial ...
Samanta Plavina, Daniela Malakovska, Jolanta Kalnina, Ilva Trapina, Elina Leonova, Mohammed Habib, Susanne Schifmann, Jegors Paramonovs, Nikolajs Sjakste, Yegor Vassetzky, Emmanuel Drouet, Natalia Paramonova   +11 more
wiley   +1 more source

A potential role for β- and γ-crystallins in the vascular remodeling of the eye

, 2005
International audienceWe demonstrate that expression of beta- and gamma-crystallins is associated with intraocular vessels during normal vascular development of the eye and also in the Nuc1 rat, a mutant in which the hyaloid vascular system fails to ...
Zigler, J. Samuel, Sinha, Debasish, Zhang, Cheng, Zigler, J Samuel, Nath, Avindra, Fariss, Robert, Goldberg, Morton, Gehlbach, Peter, Gongora, Celine, Cano, Marisol, Hose, Stacey, Green, William   +11 more
core   +1 more source

GABAergic Network Dysregulation in Alcohol Use Disorder: Receptor–Transporter Interactions Driving the Transition From Goal‐Directed to Compulsive Behaviour

Addiction Biology, Volume 31, Issue 11, November 2026.
Astrocytic GAT3 regulates ambient GABA levels in the globus pallidus externus (GPe). Reduced GAT3 function enhances extrasynaptic GABAergic signalling and disrupts subthalamic nucleus (STN) regulation and cortical signal fidelity.ABSTRACTAlcohol use disorder (AUD) is characterized by a shift from controlled, goal‐directed drinking to compulsive ...
Hannah Aranda, Nathan Jones, Humza Haroon, Doo‐Sup Choi   +3 more
wiley   +1 more source

Calcium binding properties of beta-crystallins

, 1996
β-Crystallins, the oligomeric proteins of the eye lens, were found to bind calcium ions with low affinity, in the millimolar range. Calcium was found to induce conformational changes in the secondary and tertiary structure of β-crystallins.
Balasubramanian, D., Sharma, Yogendra, Yogendra Sharma, D. Balasubramanian   +3 more
core   +1 more source