Results 81 to 90 of about 18,186 (212)

Molecular Chaperone Networks in Plants: Maintaining Proteostasis and Enhancing Stress Resilience for Crop Improvement

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Molecular chaperones play a central role in the plant proteostasis machinery by aiding the folding of nascent proteins, preventing aggregation, and repairing or degrading damaged proteins. These functions are especially essential during abiotic and biotic stress, which can destabilise cellular proteins and disrupt metabolic homoeostasis.
Mingfang Yang   +10 more
wiley   +1 more source

Structural integrity of the Greek key motif in βγ-crystallins is vital for central eye lens transparency. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND: We highlight an unrecognized physiological role for the Greek key motif, an evolutionarily conserved super-secondary structural topology of the βγ-crystallins.
Venkata Pulla Rao Vendra   +5 more
doaj   +1 more source

The Role of Gene Flow in the Diversification of the Monkey Treefrog Complex Across the South American Dry Diagonal

open access: yesZoologica Scripta, Volume 55, Issue 4, Page 568-588, July 2026.
ABSTRACT Understanding Neotropical megadiversity remains challenging due to fundamental taxonomic issues, including identifying and describing cryptic species and their distribution, and the limited knowledge of key factors driving biological diversification. Such challenges are especially prominent in diverse clades with high levels of cryptic species,
Felipe Camurugi   +10 more
wiley   +1 more source

Development of an immunoanalytical method for the detection of β- and γ- Crystallins and anti-crystallin antibodies. A molecular biomarker for cataract

open access: yesIndian Journal of Ophthalmology, 2002
Purpose: To develop and evaluate an immunoanalytical method for the detection of β - and g-crystallins and anti-crystallin antibodies. Materials and Methods: Beta and g-crystallins isolated from rat lens were used as immunogens to raise ...
Nayak Sujatha   +2 more
doaj  

A novel non-lens betagamma-crystallin and trefoil factor complex from amphibian skin and its functional implications. [PDF]

open access: yesPLoS ONE, 2008
In vertebrates, non-lens betagamma-crystallins are widely expressed in various tissues, but their functions are unknown. The molecular mechanisms of trefoil factors, initiators of mucosal healing and being greatly involved in tumorigenesis, have remained
Shu-Bai Liu   +6 more
doaj   +1 more source

Racemisation of Amino Acids: From Synthetic Challenge to Biological Significance

open access: yesChemBioChem, Volume 27, Issue 11, 15 June 2026.
Racemisation, once considered an undesirable synthetic side reaction, also occurs naturally in amino acids and influences biological processes. Evidence links stereochemical conversion to ageing, protein turnover, and cellular development. This review examines mechanisms, control strategies in synthesis, applications and implications in physiology ...
Othman Al Musaimi
wiley   +1 more source

Characterization of γ-crystallins from eye lenses of shark: closer structural similarity to mammalian than other piscine γ-crystallins?

open access: yes, 1989
Lens crystalline were isolated and characterized from sharks of the cartilaginous fishes. Four crystallin fractions corresponding to α-,⨿H-,βL- and γ-crystallins, similar to those of mammalian crystallins, were obtained.
Chiou, S.-H., S.-H. Chiou
core   +1 more source

MALDI imaging mass spectrometry of β‐ and γ‐crystallins in the ocular lens

open access: yes, 2020
Lens crystallin proteins make up 90% of expressed proteins in the ocular lens and are primarily responsible for maintaining lens transparency and establishing the gradient of refractive index necessary for proper focusing of images onto the retina.
Paul J. Donaldson   +11 more
core   +1 more source

Copper reductase activity and free radical chemistry by cataract-associated human lens γ-crystallins

open access: yes, 2022
Cataracts are caused by high-molecular weight aggregates of human eye lens proteins that scatter light, causing lens opacity. Metal ions have emerged as important potential players in the etiology of cataract disease, as human lens γ-crystallins are ...
Giovanni, Palomino-Vizcaino   +9 more
core   +1 more source

Metal‐Dependent Effects and Crowding Robustness of Pseudomonas fluorescens Esterase I

open access: yesChemBioChem, Volume 27, Issue 11, 15 June 2026.
Pseudomonas fluorescens esterase I retains catalytic activity in metal‐rich and crowded environments, despite metal‐specific inhibitory effects. These findings highlight its robustness for biocatalytic applications in complex environments. Industrial biocatalysts are strongly influenced by their physicochemical environment, yet systematic studies on ...
Emmanouil Ntermanakis   +6 more
wiley   +1 more source

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