Results 101 to 110 of about 18,186 (212)
The crystallins: Genes, proteins and diseases.
, 1997 The crystallins were discovered as the structural proteins of the vertebrate eye lens in the last century by C.T. Mörner (Z. Physiol. Chem. 18, 1893, 61-106).
Graw, J.
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New focus on alpha-crystallins in retinal neurodegenerative diseases
Experimental Eye Research, 2010 The crystallin proteins were initially identified as structural proteins of the ocular lens and have been recently demonstrated to be expressed in normal retina.
P. Fort, K. Lampi
semanticscholar +1 more source
Dysregulation of Non‐Muscle Myosin IIA Assembly and Phosphorylation in S100A4 Null Mouse Lens
Journal of Cellular Physiology, Volume 241, Issue 6, June 2026.This study identifies S100A4 as a critical regulator of NMIIA assembly, phosphorylation, and actin cytoskeletal organization in the ocular lens. Loss of S100A4 disrupts lens fiber cell architecture and impairs lens transparency, revealing a previously unrecognized role for S100A4 in maintaining lens homeostasis and structural integrity.
Rupalatha Maddala +3 more
wiley +1 more source
Post-translationally modified human lens crystallin fragments show aggregation in vitro
Biochemistry and Biophysics Reports, 2017 Background: Crystallin fragments are known to aggregate and cross-link that lead to cataract development. This study has been focused on determination of post-translational modifications (PTMs) of human lens crystallin fragments, and their aggregation ...
O.P. Srivastava +3 more
doaj +1 more source
Light-Induced Phosphorylation of Crystallins in the Retinal Pigment Epithelium
International Journal of Biological Macromolecules, 2010 Protein phosphorylations have essential regulatory roles in visual signaling. Previously, we found that phosphorylation of several proteins in the retina and the retinal pigment epithelium (RPE) is involved in anti-apoptotic signaling under oxidative ...
Hyunju Lee +3 more
semanticscholar +1 more source
Staling Behavior of Chickpea‐Enriched Bread: A Dynamic Mechanical Analysis Approach
Legume Science, Volume 8, Issue 2, June 2026.ABSTRACT Bread is a staple food widely consumed worldwide and therefore represents an excellent vehicle for increasing nutrient intake. In this context, the incorporation of chickpea flour into bread offers promising nutritional benefits; however, its impact on bread technological quality remains underexplored. This study investigated staling phenomena
Marcello Gigliotti +2 more
wiley +1 more source
The role of the nucleus in the control of mitochondrial precursor proteins in yeast
Protein Science, Volume 35, Issue 6, June 2026.Abstract Mitochondria are essential organelles of eukaryotic cells, with vital roles in energy production, biosynthesis of macromolecules, and intracellular signaling. Their function depends on a complex proteome with proteins targeted to different mitochondrial sub‐compartments.
Kira Ritzenhofen +3 more
wiley +1 more source
In vivo substrates of the lens molecular chaperones αA-crystallin and αB-crystallin.
PLoS ONE, 2014 αA-crystallin and αB-crystallin are members of the small heat shock protein family and function as molecular chaperones and major lens structural proteins.
Usha P Andley +2 more
doaj +1 more source
Aging Cell, Volume 25, Issue 6, June 2026.The molecular mechanisms of RORA targeting PRNP activate oxidative injury‐induced cellular senescence and apoptosis of lens epithelial cells. Current research confirms that the transcription factor RORA targets PRNP, exacerbating cellular senescence and apoptosis of LECs (Figure 7).
Yue Zou +11 more
wiley +1 more source
Physiological expression of lens α-, β-, and γ-crystallins in murine and human corneas
, 2020 Purpose: How corneal transparency is formed/maintained remains largely unclear. A group of enzymes which are referred to as enzymatic crystallins were proposed to contribute to corneal transparency in various animals.
Changkai Jia +4 more
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