Results 161 to 170 of about 485,962 (354)

Crystalline‐Amorphous Heterostructure: A Novel Configuration for Silver Nanoclusters

open access: yesAdvanced Science, EarlyView.
This study presents a spontaneously formed amorphous‐crystalline heterostructure composite composed of atomically precise carboranylthiolate‐protected silver NCs, demonstrating not only a unique co‐assembly of distinct metal NCs at the macroscopic level but also promising potential applications of metal cluster‐based materials.
Jia‐Hong Huang   +4 more
wiley   +1 more source

Human Nervous System‐Based Biohybrid Robot‐On‐A‐Chip with Sensing Function for Toxicity Screening

open access: yesAdvanced Science, EarlyView.
Human nervous system‐based biohybrid robot‐on‐a chip with eye function as sensing system in addition to brain/motor neuron/muscle functions is proposed. Upon light stimulation, the eye assembloid generates electrophysiological signals, which are transmitted through the cerebral organoid and motor neuron spheroid, inducing muscle movement.
Minkyu Shin   +6 more
wiley   +1 more source

Dynamic Cap‐Mediated Substrate Access and Potent Inhibitor Design of Monkeypox Virus I7L Protease

open access: yesAdvanced Science, EarlyView.
The first crystal structure of MPXV I7L protease, revealing its unique dimeric form is resolved. The structures and MD simulations uncovered a dynamic cap region that regulates substrate access to the active site. The structural basis of substrate recognition and the catalytic mechanism are elucidated, which led to the development of a FRET‐based assay
Haixia Su   +12 more
wiley   +1 more source

Infrared protein crystallography [PDF]

open access: yes, 2011
McGeehan, John   +5 more
core   +1 more source

Trimerization of 1,2‐Diaminocyclohexane Catalyzed by a Metal–Organic Cage Tandem Catalyst with Dual Biomimetic Active Sites

open access: yesAdvanced Science, EarlyView.
Dual biomimetic active sites, i.e., mononuclear {ZnII(L)(H2O)} and dinuclear {L2ZnII(CHO2)(OH)ZnIIL2}, have been successfully intergrated into a metal–organic cage, Zn20‐MOC. These two different active sites in Zn20‐MOC catalyze different steps of cascade trimerization of 1,2‐diaminocyclohexane. The mononuclear {ZnII(L)(H2O)} site catalyzes the initial
Xiao‐Jun Chai   +10 more
wiley   +1 more source

Water‐Catalytic Deconstructive and Proton Transfer Cyclopropanation of Sulfoxonium Ylide with Olefin

open access: yesAdvanced Science, EarlyView.
Water‐catalytic deconstructive and proton transfer cyclopropanation of sulfoxonium ylide with olefin is developed through a sequential water‐mediated ring‐closing/opening reaction. This atom‐economical, environmentally friendly methodology offers easy access to a range of cyclopropyl ketones with moderate to good yields.
Xianglin Yu   +4 more
wiley   +1 more source

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