Results 191 to 200 of about 491,196 (368)

Dimer‐Specific FokT‐seq Reveals DNA‐Binding Dimerization and Novel Genomic Targets of TDP‐43

open access: yesAdvanced Science, EarlyView.
Loss of TDP‐43 dimerization is implicated in ALS, yet its mechanistic role remains elusive. This study introduces FokT, a novel system that restores TDP‐43 dimerization to map its DNA targets via FokT‐seq. The findings uncover key binding sites and offer a versatile tool for exploring dimer‐dependent transcriptional regulation.
Mingming Yang   +4 more
wiley   +1 more source

Band structure diagram paths based on crystallography [PDF]

open access: yes, 2016
Y. Hinuma   +4 more
semanticscholar   +1 more source

Dual Regulation of Molecular Rigidity and Orbital Engineering of Pt(II) Emitters for High‐Performance Deep‐Blue OLEDs

open access: yesAdvanced Science, EarlyView.
Four novel tetradentate Pt(II) emitters (PtCY, PtCY‐F, PtCY‐tBu, PtCY‐tBuF) are designed through synergistic strategy of molecular orbital engineering and steric hindrance effect. PtCY‐tBuF‐based device B4 achieves a high maximum luminance of 45 621 cd m−2, and record high external quantum efficiency (EQE) of 27.1%, 24.3%, and 21.7% at high brightness ...
Chengyao Zhang   +4 more
wiley   +1 more source

Infrared protein crystallography [PDF]

open access: yes, 2011
McGeehan, John   +5 more
core   +1 more source

International tables for X-ray crystallography

open access: yes, 1962
N. F. M. Henry   +6 more
semanticscholar   +1 more source

An Aptamer‐Based EXACT Anticoagulant as a Sustainable, Animal‐Free Alternative to Unfractionated Heparin

open access: yesAdvanced Science, EarlyView.
By simply conjugating thrombin's active‐site inhibitor, dabigatran, with an exosite inhibitor, aptamer HD1, the resulting EXosite‐ACTive site (EXACT) inhibitors show two orders of magnitude higher potency and selectivity via synergistic binding, while maintaining the aptamer's antidote‐reversible trait, yielding a potential substitute for the animal ...
Haixiang Yu   +11 more
wiley   +1 more source

Inhaling Eugenol Inhibits NAFLD by Activating the Hepatic Ectopic Olfactory Receptor Olfr544 and Modulating the Gut Microbiota

open access: yesAdvanced Science, EarlyView.
Inhalable eugenol (EUG) from clove oil attenuates NAFLD by activating hepatic olfactory receptor Olfr544, triggering cAMP/PKA/CREB signaling to enhance lipolysis/oxidation. EUG concurrently restores gut microbiota, enriching probiotics (L. reuteri XR23/L. johnsonii XR25) and metabolites (IPA/5‐HIAA) that suppress lipogenesis.
Xiao‐Ran Wang   +15 more
wiley   +1 more source

Durable Lithium Metal Anodes Enabled by {110}‐Textured Epitaxy on a LiF@Ag Commensurate Heterostructure

open access: yesAdvanced Science, EarlyView.
Utilizing their commensurate lattices, a LiF@Ag heterostructure is fabricated for Li epitaxy, featuring Ag nanoparticles grown on 2D LiF layers. The composition pinning effect inhibits Li‐Ag alloying and maintains the high lithiophilicity and fast adatom migration associated with Ag.
Liming Zhang   +7 more
wiley   +1 more source

Binary nickel alloy phase diagrams compilation and critical evaluation [PDF]

open access: yes
Equilibrium diagrams general features, intermediate phases, liquidus and solidus, terminal solid solutions, metastable phases, crystallography, and thermodynamics are ...
Hontas, J.
core   +1 more source

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