Results 191 to 200 of about 491,196 (368)
Dimer‐Specific FokT‐seq Reveals DNA‐Binding Dimerization and Novel Genomic Targets of TDP‐43
Loss of TDP‐43 dimerization is implicated in ALS, yet its mechanistic role remains elusive. This study introduces FokT, a novel system that restores TDP‐43 dimerization to map its DNA targets via FokT‐seq. The findings uncover key binding sites and offer a versatile tool for exploring dimer‐dependent transcriptional regulation.
Mingming Yang +4 more
wiley +1 more source
Band structure diagram paths based on crystallography [PDF]
Y. Hinuma +4 more
semanticscholar +1 more source
Four novel tetradentate Pt(II) emitters (PtCY, PtCY‐F, PtCY‐tBu, PtCY‐tBuF) are designed through synergistic strategy of molecular orbital engineering and steric hindrance effect. PtCY‐tBuF‐based device B4 achieves a high maximum luminance of 45 621 cd m−2, and record high external quantum efficiency (EQE) of 27.1%, 24.3%, and 21.7% at high brightness ...
Chengyao Zhang +4 more
wiley +1 more source
International tables for X-ray crystallography
N. F. M. Henry +6 more
semanticscholar +1 more source
By simply conjugating thrombin's active‐site inhibitor, dabigatran, with an exosite inhibitor, aptamer HD1, the resulting EXosite‐ACTive site (EXACT) inhibitors show two orders of magnitude higher potency and selectivity via synergistic binding, while maintaining the aptamer's antidote‐reversible trait, yielding a potential substitute for the animal ...
Haixiang Yu +11 more
wiley +1 more source
Inhalable eugenol (EUG) from clove oil attenuates NAFLD by activating hepatic olfactory receptor Olfr544, triggering cAMP/PKA/CREB signaling to enhance lipolysis/oxidation. EUG concurrently restores gut microbiota, enriching probiotics (L. reuteri XR23/L. johnsonii XR25) and metabolites (IPA/5‐HIAA) that suppress lipogenesis.
Xiao‐Ran Wang +15 more
wiley +1 more source
Crystallography for Beginners, with an Appendix on the use of the Blowpipe and the Determination of Common Minerals (after the method of Dr Albin Weisbach) [PDF]
openalex +1 more source
Utilizing their commensurate lattices, a LiF@Ag heterostructure is fabricated for Li epitaxy, featuring Ag nanoparticles grown on 2D LiF layers. The composition pinning effect inhibits Li‐Ag alloying and maintains the high lithiophilicity and fast adatom migration associated with Ag.
Liming Zhang +7 more
wiley +1 more source
Binary nickel alloy phase diagrams compilation and critical evaluation [PDF]
Equilibrium diagrams general features, intermediate phases, liquidus and solidus, terminal solid solutions, metastable phases, crystallography, and thermodynamics are ...
Hontas, J.
core +1 more source

