Results 211 to 220 of about 485,962 (354)

Conformational Change in a Four‐Tetrad DNA G‐Quadruplex upon Intercalation of a Small‐Molecule Ligand PyDH2

open access: yesAngewandte Chemie, EarlyView.
An exception or the rule? This work represents a second observation, and the first crystallographic evidence, of true intercalation of a small‐molecule ligand (here, bisquinolinium PyDH2) into an antiparallel G‐quadruplex (G4) DNA fold. Abstract G‐quadruplexes (G4s) are non‐canonical DNA structures implicated in a number of biological processes.
Kailey N. Martin   +7 more
wiley   +2 more sources

Reshaping Protein‐Based Nanoparticles: Innovative Artificial Intelligence‐Driven Strategies for Structural Design and Applications

open access: yesAdvanced NanoBiomed Research, EarlyView.
Artificial Intelligence‐driven advancements in protein‐based nanoparticle design enable exceptional functionalities, overcoming traditional challenges and expanding nanomedicine applications. Nanoparticles (NPs) have become a pivotal technology in biomedical research due to their unique physicochemical properties and nanoscale size, allowing for ...
Mohammad Mahmoudi Gomari   +3 more
wiley   +1 more source

Linking Metallacycle Transfer with Ring‐Opening Metathesis to Generate Polyacetylenes of Unprecedented Structure

open access: yesAngewandte Chemie, EarlyView.
A series of unusual low HOMO‐LUMO gap polyacetylenes bearing ring‐fused tellurophene and vinyl side chains were prepared by combining metallacycle transfer (Hf/p‐block element exchange) with ring‐opening metathesis polymerization (ROMP) into a single modular and efficient protocol.
Abhishek V. Muralidharan   +2 more
wiley   +2 more sources

Advances in structural science: Education, outreach, and research applications. [PDF]

open access: yesStruct Dyn
Bou-Nader C   +12 more
europepmc   +1 more source

Nanostructured Biomaterial‐Based Approaches to Support Induced Pluripotent Stem Cell Differentiation

open access: yesAdvanced NanoBiomed Research, EarlyView.
Induced pluripotent stem cells (iPSCs), reprogrammed from adult somatic cells, represent an innovative approach for regenerative medicine and biomedical applications. This review highlights the importance of nanostructured biomaterials, utilized as delivery systems or scaffolds, in supporting iPSC differentiation and fate through structural and ...
Beatriz A. B. R. Passos   +2 more
wiley   +1 more source

Breaking Bonds at Tin(II): Reductive or Oxidative Addition?

open access: yesAngewandte Chemie, EarlyView.
Typically, the addition of a chemical bond to a metal centre is assumed─without question─to be an oxidative process. Here, through studies of bond addition to tin(II), we reveal a spectrum ranging from ‘oxidative’ (Cl─Cl) to ‘reductive’ (Be─Be) processes, with other bonds (B─B, B─H, H─H) falling between these two extremes.
Maximilian Dietz   +3 more
wiley   +2 more sources

Home - About - Disclaimer - Privacy