Correlation Between Paravertebral Muscles Degeneration and Spinopelvic Parameters in Patients With Osteoporotic Vertebral Compression Fractures. [PDF]
Miao DC +4 more
europepmc +1 more source
The epigenetic landscape of skeletal muscle in response to exercise and aging
Epigenetic mechanisms regulate gene expression in response to exercise and aging, thereby supporting skeletal muscle plasticity. Acute exercise induces chromatin remodeling through histone modifications and DNA methylation, promoting the expression of exercise‐responsive genes.
Sabrina Champsi, David A. Hood
wiley +1 more source
Safety profiles of cyclosporine and tacrolimus in pregnancy: a pharmacovigilance analysis using the FDA Adverse Event Reporting System. [PDF]
Deng Y +7 more
europepmc +1 more source
Bringing Gene Therapy Into Real World Clinical Practice
ABSTRACT Introduction Adeno‐associated virus (AAV)‐based gene therapy for haemophilia has shifted therapeutic paradigms by enabling hepatic gene transfer, restoring endogenous clotting factor expression, and reducing reliance on conventional prophylactic treatments. Two products, valoctocogene roxaparvovec (haemophilia A) and etranacogene dezaparvovec (
Wolfgang Miesbach +2 more
wiley +1 more source
Cyclosporine A for Recurrent Spontaneous Abortion: A Systematic Review and Meta-Analysis. [PDF]
Huang S, Song Y, Cai A, Ning Y.
europepmc +1 more source
Current State of Moderate Congenital Haemophilia A and the Need for Preventive Treatment
ABSTRACT Introduction The severity of haemophilia A is classified by the degree of factor VIII (FVIII) deficiency, rather than by clinical manifestations. However, FVIII activity alone does not necessarily accurately reflect clinical severity such as bleeding tendency, and patients with mild‐to‐moderate haemophilia A can experience significant disease ...
Masahiro Takeyama +6 more
wiley +1 more source
Spinal Muscle Health in Chronic Low Back Pain: An Integrated Narrative Review of Muscle Quality, Function, and Clinical Implications. [PDF]
Rossi M +9 more
europepmc +1 more source
ABSTRACT Documenting how judges explain child sexual abuse (CSA) perpetration is an important task as sentencing decisions are informed by their explanatory understandings. Despite this, the research into judges’ explanations for CSA perpetration is piecemeal and dated.
Kelly Richards
wiley +1 more source

