Impact of Shunt Placement on CSF Dynamics [PDF]
Biomedicines, 2023 Background: CSF dynamics are disturbed in chronic hydrocephalus (NPH). We hypothesise that these alterations reflect a disturbance of intracranial compliance.
Cyrille Capel +4 more
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CSF dynamics throughout the ventricular system using 4D flow MRI: associations to arterial pulsatility, ventricular volumes, and age [PDF]
Fluids and Barriers of the CNSBackground Cerebrospinal fluid (CSF) dynamics are increasingly studied in aging and neurological disorders. Models of CSF-mediated waste clearance suggest that altered CSF dynamics could play a role in the accumulation of toxic waste in the CNS, with ...
Tomas Vikner +8 more
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CSF dynamics as a predictor of cognitive progression [PDF]
NeuroImage, 2021 Disproportionately enlarged subarachnoid-space hydrocephalus (DESH), characterized by tight high convexity CSF spaces, ventriculomegaly, and enlarged Sylvian fissures, is thought to be an indirect marker of a CSF dynamics disorder.
Petrice M. Cogswell +10 more
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Dynamic compliance of the CSF system in iNPH (Part I) - in vitro investigation of the impact of spinal canal stenoses [PDF]
Fluids and Barriers of the CNSSpinal canal stenosis is an age-related degenerative condition observed mainly in the cervical and lumbar regions. Recent research has suggested that such stenoses influence cerebrospinal fluid (CSF) dynamics in idiopathic normal pressure hydrocephalus ...
Anne E. Benninghaus +6 more
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Neurobiology of Disease, 2022 Cerebrospinal fluid (CSF), predominantly produced in the ventricles and circulating throughout the brain and spinal cord, is a key protective mechanism of the central nervous system (CNS).
Neel H. Mehta +12 more
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Enhanced in vitro model of the CSF dynamics [PDF]
Fluids and Barriers of the CNS, 2019 Background Fluid dynamics of the craniospinal system are complex and still not completely understood. In vivo flow and pressure measurements of the cerebrospinal fluid (CSF) are limited. Whereas in silico modeling can be an adequate pathway for parameter
Anne Benninghaus +5 more
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Cerebrospinal fluid dynamics and brain function regulation: from homeostasis to neurological disorders [PDF]
Frontiers in NeuroscienceCerebrospinal fluid (CSF) is increasingly recognized as an active regulator of brain function rather than a passive mechanical buffer. Beyond its classical roles in cushioning the brain and removing metabolic waste, CSF participates in a tightly coupled ...
Yu Yang +8 more
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CSF Dynamics for Shunt Prognostication and Revision in Normal Pressure Hydrocephalus [PDF]
Journal of Clinical Medicine, 2021 Afroditi-Despina Lalou +2 more
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Potential association among posterior fossa bony volume and crowdedness, tonsillar hernia, syringomyelia, and CSF dynamics at the craniocervical junction in Chiari malformation type I [PDF]
Frontiers in Neurology, 2023 Tao Fan
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Mechanistic multiphysics modeling reveals how blood pulsation drives CSF flow, pressure, and brain deformation under physiological and injection conditions [PDF]
Fluids and Barriers of the CNSIntrathecal (IT) injection is an effective way to deliver drugs to the brain bypassing the blood-brain barrier (BBB). To evaluate and optimize IT drug delivery, it is necessary to understand the cerebrospinal fluid (CSF) dynamics in the central nervous ...
Zhuogen Li, Keyu Feng, Hector Gomez
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