Results 31 to 40 of about 51,438 (203)

Estimation of the Lethality Rate, Recovery Rate, and Case Fatality Ratio of Classical Swine Fever in Japanese Wild Boar: An Analysis of the Epidemics From September 2018 to March 2019

Frontiers in Veterinary Science, 2021
Understanding the morbidity and lethality of diseases is necessary to evaluate the effectiveness of countermeasure against the epidemics (e.g., vaccination).
Ryota Matsuyama, Takehisa Yamamoto, Yoko Hayama, Ryosuke Omori   +3 more
doaj   +1 more source

Intrathecal Contrast-Enhanced Magnetic Resonance Imaging of Cerebrospinal Fluid Dynamics and Glymphatic Enhancement in Idiopathic Normal Pressure Hydrocephalus

Frontiers in Neurology, 2022
Idiopathic normal pressure hydrocephalus (iNPH) is a neurodegenerative disease, characterized by cerebrospinal fluid (CSF) flow disturbance. Today, the only available treatment is CSF diversion surgery (shunt surgery).
Per Kristian Eide, Per Kristian Eide, Aslan Lashkarivand, Aslan Lashkarivand, Åsmund Aleksander Hagen-Kersten, Øivind Gjertsen, Bård Nedregaard, Ruth Sletteberg, Grethe Løvland, Svein Are Sirirud Vatnehol, Svein Are Sirirud Vatnehol, Are Hugo Pripp, Are Hugo Pripp, Lars Magnus Valnes, Geir Ringstad, Geir Ringstad   +15 more
doaj   +1 more source

Functional modeling of the craniospinal system for in-vitro parameter studies on the pathogenesis of NPH

Current Directions in Biomedical Engineering, 2017
Normal Pressure Hydrocephalus (NPH) has become a common disease in the elderly coming along with typical symptoms of dementia, gait ataxia and urinary incontinence, which make the differential diagnosis with other forms of dementia difficult. Furthermore
Benninghaus Anne, Goffin Christine, Leonhardt Steffen, Radermacher Klaus   +3 more
doaj   +1 more source

Treadmill locomotion in the American alligator (Alligator mississippiensis) produces dynamic changes in intracranial cerebrospinal fluid pressure

Scientific Reports, 2022
To examine the influence of movement on cerebrospinal fluid (CSF) dynamics, intracranial subdural pressure recordings were taken from sub-adult alligators (Alligator mississippiensis) locomoting on a treadmill. Pressure recordings documenting the cardiac,
Bruce A. Young, Michael J. Cramberg
doaj   +1 more source

Granulocyte-colony stimulating factor gene therapy as a novel therapeutics for stroke in a mouse model

Journal of Biomedical Science, 2020
Background Global ischemia is the resulting effect of a cardiopulmonary arrest (CPA). Presently there is no effective treatment to address neurological deficits in patients who survived a CPA.
Janet M. Menzie-Suderam, Jigar Modi, Hongyaun Xu, Andrew Bent, Paula Trujillo, Kristen Medley, Eugenia Jimenez, Jessica Shen, Michael Marshall, Rui Tao, Howard Prentice, Jang-Yen Wu   +11 more
doaj   +1 more source

Lumbar and ventricular CSF concentrations of extracellular matrix proteins before and after shunt surgery in idiopathic normal pressure hydrocephalus

Fluids and Barriers of the CNS, 2021
Background Idiopathic normal pressure hydrocephalus (iNPH) is a reversible CNS disease characterized by disturbed cerebrospinal fluid (CSF) dynamics. Changes in the extracellular matrix (ECM) composition might be involved in the pathophysiology of iNPH ...
Karolina Minta, Anna Jeppsson, Gunnar Brinkmalm, Erik Portelius, Henrik Zetterberg, Kaj Blennow, Mats Tullberg, Ulf Andreasson   +7 more
doaj   +1 more source

Cerebrospinal fluid dynamics and intracranial pressure elevation in neurological diseases

Fluids and Barriers of the CNS, 2019
The fine balance between the secretion, composition, volume and turnover of cerebrospinal fluid (CSF) is strictly regulated. However, during certain neurological diseases, this balance can be disrupted.
Steven William Bothwell, Damir Janigro, Adjanie Patabendige   +2 more
doaj   +1 more source

The impact of spinal cord nerve roots and denticulate ligaments on cerebrospinal fluid dynamics in the cervical spine.

PLoS ONE, 2014
Cerebrospinal fluid (CSF) dynamics in the spinal subarachnoid space (SSS) have been thought to play an important pathophysiological role in syringomyelia, Chiari I malformation (CM), and a role in intrathecal drug delivery.
Soroush Heidari Pahlavian, Theresia Yiallourou, R Shane Tubbs, Alexander C Bunck, Francis Loth, Mark Goodin, Mehrdad Raisee, Bryn A Martin   +7 more
doaj   +1 more source

Assessing pulsatile waveforms of paravascular cerebrospinal fluid dynamics using dynamic diffusion‐weighted imaging (dDWI)

NeuroImage, 2022
Cerebrospinal fluid (CSF) in the paravascular spaces of the surface arteries (sPVS) is a vital pathway in brain waste clearance. Arterial pulsations may be the driving force of the paravascular flow, but its pulsatile pattern remains poorly characterized,
Qiuting Wen, Yunjie Tong, Xiaopeng Zhou, Mario Dzemidzic, Chang Yueh Ho, Yu-Chien Wu   +5 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source