Cardiovascular toxicity from immune checkpoint inhibitor therapy: an inflammatory continuum
British Journal of Pharmacology, EarlyView.Immune checkpoint inhibitor (ICI) therapy has markedly improved outcomes in advanced malignancies but has also revealed a distinct spectrum of cardiovascular immune‐related adverse events. Myocarditis represents the most severe manifestation, while non‐inflammatory left ventricular dysfunction and vascular inflammation have emerged as additional ...
Fabrice Reyes +7 more
wiley +1 more source
Efficacy of a novel drainage catheter in the treatment of CSF leak after posterior spine surgery: A retrospective cohort study. [PDF]
Open Med (Wars)Yang S, Zhu Z, Chen G, Long Z.
europepmc +1 more source
Progressive superficial siderosis from Chronic CSF leak as a long-term complication of cervical anterior corpectomy: A case report and review of the literature. [PDF]
Surg Neurol Int, 2022 McMahon PW +6 more
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British Journal of Pharmacology, EarlyView.The current obesity drug landscape, dominated by GLP‐1 receptor agonists and emerging multi‐agonist therapies, has reinforced that long‐term weight loss is achieved in large part through central mechanisms that suppress appetite and reshape energy balance.
Ines Martinez‐Corral +3 more
wiley +1 more source
Clinical Impact of Hydroxyapatite on the Outcome of Skull Base Reconstruction for Intraoperative High-Flow CSF Leak: A Propensity Score Matching Analysis. [PDF]
Front Oncol, 2022 Lee SH +7 more
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Alamandine/MrgD pathway modulates gut–bone marrow axis in ageing
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Ageing is associated with colon epithelial barrier disruption and up‐regulation of myelopoiesis in the bone marrow (BM). Alamandine (Ala) and MrgD are novel members of the renin angiotensin system (RAS). This study tested the hypothesis that Ala restores the colon epithelial barrier integrity in ageing via modulating gut–
Kishore Chittimalli +6 more
wiley +1 more source
Successful surgical management of a complex temporal bone defect with brain contusion, meningocele, and CSF leak: A case report. [PDF]
Int J Surg Case RepHasan B, Jourieh M, Hamdan J.
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The fight of innate immunity and abnormal cannabinoids against Candida infection
British Journal of Pharmacology, EarlyView.Candida species represent the most clinically significant fungal pathogens in humans, with invasive candidiasis carrying a mortality of 30%–40% in critically ill patients despite modern antifungal therapy. The innate immune system – through the coordinated and specific activities of neutrophils, macrophages, NK cells, mast cells and eosinophils ...
Prince Ofori +2 more
wiley +1 more source
Volumetric Changes in the Choroid Plexus Associated with Spontaneous Intracranial Hypotension in Patients with Spinal CSF Leak. [PDF]
AJNR Am J NeuroradiolMehan WA, Poyiadji N, Paul AB, Buch K.
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A Cross‐Sectional Study of Patient Views on Acceptability of Olfactory Implants
Clinical Otolaryngology, EarlyView.ABSTRACT Objectives Unlike other chronic conditions, effective therapies for smell and taste disorders (SATDs) remain scarce. Olfactory implants are an emerging area of therapy aimed at restoring the sense of smell through electrical stimulation of the olfactory pathway.
Gabija Klyvyte +9 more
wiley +1 more source