Results 41 to 50 of about 2,018 (187)

A small CSN3-containing complex, but not the CSN, is affected by the csn3-3 mutation.

open access: yes, 2013
Protein extracts from 7-d.o. Col, csn1-10 and csn3-3 seedlings were fractionated on a Superdex-200 gel filtration column and fractions (4 to 19) were collected and blotted with α-CSN1, α-CSN4, and α-CSN8 (A), α-CSN5 (B) and α-CSN3 (C).
He Huang (50693)   +2 more
core   +1 more source

The CSN3 subunit plays multiple roles in auxin signaling.

open access: yes, 2013
We hypothesize that in addition to its role in the CSN as a cullin deneddylase, the CSN3 subunit also regulates auxin signaling independently of the SCFTIR1/AFB ubiquitin-ligase.
He Huang (50693)   +2 more
core   +1 more source

INFLUENCE OF CSN3 MARKER ON MILK COMPOSITION IN ROMANIAN BROWN AND ROMANIAN SIMMENTAL CATTLE FROM S.C.D.C.B. ARAD

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
Milk yield and composition in cattle are typical quantitative traitswhich are influenced by environmental factors and allelic variations. K-casein is a protein expressed in milk and, due to is polymorphism, may serve as a molecular marker for yield ...
DANIELA E. ILIE   +4 more
doaj  

Effects of CSN3 and LGB gene polymorphisms on production traits in beef cattle [PDF]

open access: yesGenetics and Molecular Biology, 2005
The objective of the present study was to estimate the allele and genotype frequencies of the CSN3/HinfI and LGB/HaeIII gene polymorphisms in beef cattle belonging to different genetic groups, and to determine the effects of these polymorphisms on growth and carcass traits in these animals, which are submitted to an intensive production model ...
Curi, Rogerio Abdallah   +4 more
openaire   +4 more sources

Cell-specific and shared regulatory elements control a multigene locus active in mammary and salivary glands

open access: yesNature Communications, 2023
Regulation of high-density loci harboring genes with different cell-specificities remains a puzzle. Here we investigate a locus that evolved through gene duplication and contains eight genes and 20 candidate regulatory elements, including one super ...
Hye Kyung Lee   +3 more
doaj   +1 more source

Integrated Single‐Nucleus Multi‐Omics Atlases Reveal Lineage Plasticity and Regulatory Networks of Luminal Epithelial Cells During Mammary Gland Lactation and Involution

open access: yesAdvanced Science, EarlyView.
This study integrates single‐cell multi‐omics, spatial transcriptomics, and cross‐species comparative analyses to systematically characterize the cellular composition and differentiation trajectories of goat mammary epithelial cells, along with the gene regulatory networks and intercellular communication mechanisms governing these trajectories, thereby
Xiaoru Yan   +12 more
wiley   +1 more source

Function of COP9 signalosome in regulation of mouse oocytes meiosis by regulating MPF activity and securing degradation. [PDF]

open access: yesPLoS ONE, 2011
The COP9 (constitutive photomorphogenic) signalosome (CSN), composed of eight subunits, is a highly conserved protein complex that regulates processes such as cell cycle progression and kinase signalling.
Eunju Kim   +6 more
doaj   +1 more source

Arabidopsis inositol polyphosphate kinase activities regulate COP9 deneddylation functions in phosphate homeostasis

open access: yesJournal of Integrative Plant Biology, EarlyView.
Plant phosphate (Pi) homeostasis relies on coordinated activities of the inositol polyphosphate kinases IPK1 and ITPK1, which balance localized InsP7 biosynthesis to control COP9 signalosome (CSN)‐dependent deneddylation of cullin 1 (CUL1). Perturbation of this equilibrium affects the stability of SPX4, a key negative regulator of phosphate starvation ...
Yashika Walia   +12 more
wiley   +1 more source

Mitochondria Dictate Progressive Versus Bimodal Aging of the Mammary Gland

open access: yesAging Cell, Volume 25, Issue 8, August 2026.
Breast cancer shows a bimodal age distribution with a peak at 45 and higher peak at 65. Using mice with different mitochondrial genomes, we show progressive and bimodal patterns of aging of the mammary gland with distinct pro‐tumorigenic age windows. This finding may shed light on the bimodal distribution in humans.
Edmund Charles Jenkins   +6 more
wiley   +1 more source

Effect and Interaction of β-Lactoglobulin, Kappa Casein, and Prolactin Genes on Milk Production and Composition of Awassi Sheep

open access: yesAnimals, 2019
A participatory animal-breeding program was applied to 9 commercial Awassi sheep flocks in Jordan. This study aimed to assess the influence of Beta-lactoglobulin (β-LG), Prolactin (PRL), and Kappa casein (CSN3) genes, genotypes and their interaction
Khaleel Jawasreh   +2 more
doaj   +1 more source

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