Results 81 to 90 of about 8,557 (171)

Combined Transcriptomic and Proteomic Forecast Analyses for Potential Biomarkers of Smoking‐Induced Benign and Malignant Transformation of Vocal Fold Lesions

World Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 12, Issue 2, Page 168-176, April 2026.
ABSTRACT Objective Laryngeal dysplasia and Reinke's edema (RE) are common vocal fold lesions associated with smoking. While the former is cancer prone, most cases of the latter do not undergo malignant transformation. Therefore, we proposed identifying biomarkers of smoking‐induced benign‐malignant transformation of vocal fold lesions.
Yun‐Yi Liu, Pei‐Yun Zhuang
wiley   +1 more source

Prediction of short- and medium-term efficacy of biosimilar infliximab therapy. Do trough levels/antidrug antibody levels or clinical/biochemical markers play a more important role? [PDF]

, 2018
K
Bene, László, Bor, Renáta, Bíró, Edina, Farkas, Klaudia, Gasztonyi, Beáta, Gecse, Krisztina B., Golovics, Petra Anna, Gönczi, Lóránt, Kristóf, Tünde, Kürti, Zsuzsanna, Lakatos, László, Lakatos, Péter László, Lovász, Barbara Dorottya, Miheller, Pál, Molnár, Tamás, Palatka, Károly, Papp, Mária, Patai, Árpád, Rutka, Mariann, Salamon, Ágnes, Szamosi, Tamás, Szepes, Zoltán, Tóth, Gábor Tamás, Vincze, Áron, Végh, Zsuzsanna   +24 more
core  

‘Communication Is Crucial’: A Qualitative Study of Patient Expectations of Diagnostic Tests in Emergency Medicine Practice

Health Expectations, Volume 29, Issue 2, April 2026.
ABSTRACT Introduction Value‐based diagnostic tests improve patient safety. Understanding patient expectations can enhance the value of diagnostic tests in Emergency Departments. The aim of this study was to explore patient expectations about diagnostic tests to inform diagnostic stewardship in emergency medicine practice. Methods A qualitative study of
Vinay Gangathimmaiah, Rebecca Evans, Tarun Sen Gupta, Karen Cupitt, Sharon Oakley, Karen Carlisle   +5 more
wiley   +1 more source

Krónikus betegségek biológiai terápiájának alkalmazásával kapcsolatos gazdasági megfontolások = Economic consideration of the implementation of biotechnological therapies in chronic diseases [PDF]

, 2014
Disszertációmban egyes krónikus betegségekben alkalmazott biológiai terápiák gazdasági, pénzügyi és költségvetési hatásaival foglalkoztam. Célkitűzés: A biológiai gyógyszerek terápiás alkalmazásáról rendelkezésre álló tudás mind Magyarországon, mind a ...
Balogh, Orsolya
core   +1 more source

A DNA‐Based Binding Assay for the m6A‐RNA Reader Proteins

ChemBioChem, Volume 27, Issue 6, 27 March 2026.
We report the structure of the m6A‐RNA reader YTHDC2 in the complex with single‐stranded DNA. We provide evidence that the readers exhibit slightly stronger affinity for 6mA‐modified DNA than RNA. Thus, we developed an FP binding assay that uses single‐stranded DNA as probe.
Rajiv Kumar Bedi, Amedeo Caflisch
wiley   +1 more source

A descriptive analysis of real-world treatment patterns of innovator (Remicade®) and biosimilar infliximab in an infliximab-naïve Turkish population

Biologics: Targets & Therapy, 2018
Yusuf Yazici,1 Lin Xie,2 Adesuwa Ogbomo,2 Lorie A Ellis,3 Kavitha Goyal,4 Amanda Teeple,5 Ece A Mutlu,6 Ismail Simsek7 1Department of Internal Medicine, Division of Rheumatology, New York University Hospital for Joint Diseases, New York, NY, USA ...
Yazici Y, Xie L, Ogbomo A, Ellis LA, Goyal K, Teeple A, Mutlu EA, Simsek I   +7 more
doaj  

Biosimilar infliximab (CT-P13) in the treatment of inflammatory bowel disease: A Norwegian observational study [PDF]

Expert Review of Gastroenterology & Hepatology, 2015
To assess the efficacy, tolerability, and safety of CT-P13 (Remsima(®)) in patients with Crohn's disease (CD) or ulcerative colitis (UC).This was a prospective observational study performed in a single center in Norway. Patients with CD (n = 46) or UC (n = 32) received CT-P13 (5 mg/kg) by intravenous infusion at weeks 0, 2, and 6.
Jørgen, Jahnsen, Trond Espen, Detlie, Simen, Vatn, Petr, Ricanek   +3 more
openaire   +2 more sources

Immune Predictors of Radiotherapy Outcomes in Cervical Cancer

Advanced Science, Volume 13, Issue 16, 18 March 2026.
This study reveals dynamic immune remodeling in cervical cancer following radiotherapy. Single‐cell analysis identifies the C3/C3AR1 axis as a central mediator of epithelial–myeloid crosstalk, whose inhibition reduces treatment efficacy in mice. Guided by these insights, the eight‐feature machine‐learning model: Cervical Cancer Radiotherapy Immune ...
Linghao Wang, Jie Zhu, Zequn Ding, Zhiyuan Xie, Xingchen Liu, Feihong Zhang, Xiaojun Liu, Yan Zhang, Haiyan Chen   +8 more
wiley   +1 more source

Biphasic Pulmonary Blastoma: A Rare Tumor With Fatal Outcome—First Reported Case From Lebanon

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Biphasic pulmonary blastoma is a rare lung malignancy, accounting for less than 0.5% of all primary lung tumors. It is characterized by a biphasic nature of those tumors that consist of an admixture of epithelial and mesenchymal components. Up to this date, no standardized treatment approach has been developed and patient's prognosis remains ...
Houssein Chahrour, Georges Nammour, Joseph A. Akiki, Mohammad H. Abbas, Wassim Hamadeh   +4 more
wiley   +1 more source

A Critical Look at Innovation Profile and Its Relationship with Pharmaceutical Industry [PDF]

, 2017
Background: The pharmaceutical sector undertakes extensive research and development (R&D). Pharmaceutical industries have continued to launch an appreciable number of new medicines, different pharmaceutical formulations, new indications and other ...
Acurcio, FdeA, Dias, CZ, Dias, EM, Godman, B, Guerra Jnr, AA, Martin, A, Prata, WM, Silvestre, RG   +7 more
core   +1 more source