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A CTC/DTC-centered temporal framework of bone metastasis: From dissemination to dormancy and reactivation. [PDF]
J Bone OncolYuan Z +7 more
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Models to study CTCs and CTC culture methods
2023The vast majority of cancer-related deaths are due to the presence of disseminated disease. Understanding the metastatic process is key to achieving a reduction in cancer mortality. Particularly, there is a need to understand the molecular mechanisms that drive cancer metastasis, which will allow the identification of curative treatments for metastatic
Cristóbal, Fernández-Santiago +2 more
openaire +2 more sources
CTC-Derived Models: A Window into the Seeding Capacity of Circulating Tumor Cells (CTCs)
Cells, 2019 Metastasis is the main cause of cancer-related death owing to the blood-borne dissemination of circulating tumor cells (CTCs) early in the process. A rare fraction of CTCs harboring a stem cell profile and tumor initiation capacities is thought to possess the clonogenic potential to seed new lesions. The highest plasticity has been generally attributed
Patrycja Pawlikowska +2 more
exaly +4 more sources
Longitudinally collected CTCs and CTC-clusters and clinical outcomes of metastatic breast cancer
Breast Cancer Research and Treatment, 2016Circulating tumor cell (CTC) is a well-established prognosis predictor for metastatic breast cancer (MBC), and CTC-cluster exhibits significantly higher metastasis-promoting capability than individual CTCs. Because measurement of CTCs and CTC-clusters at a single time point may underestimate their prognostic values, we aimed to analyze longitudinally ...
Hushan Yang, Zhaomei Mu, Chun Wang
exaly +3 more sources
CTCs in Metastatic Breast Cancer
2012Circulating tumor cells (CTCs), enumerated by the Food and Drugs Administration-cleared CellSearch(®) system, are an independent prognostic factor of progression-free survival (PFS) and overall survival (OS) in metastatic breast cancer (MBC) patients.
Giordano A., Cristofanilli M.
openaire +3 more sources
Quantum CTC's in General Relativity
General Relativity and Gravitation, 2001Closed timelike curves and their importance in theories of quantum gravity are discussed at the example of tunneling spacetimes constructed from generalized Misner spacetimes. These models are quantum mechanically stable and show negative energy densities and closed timelike curves at the Planck scale.
Garay, Luis J. +1 more
openaire +2 more sources
European Journal of Radiology, 2013
Owing to encouraging results achieved in the clinical practice, CT colonography (CTC) is being increasingly employed for the examination of the whole colon and rectum and is quickly becoming a widely accepted diagnostic technique that is replacing double contrast barium enema and appears a promising tool for colorectal cancer screening as well.
NERI, EMANUELE +5 more
openaire +3 more sources
Owing to encouraging results achieved in the clinical practice, CT colonography (CTC) is being increasingly employed for the examination of the whole colon and rectum and is quickly becoming a widely accepted diagnostic technique that is replacing double contrast barium enema and appears a promising tool for colorectal cancer screening as well.
NERI, EMANUELE +5 more
openaire +3 more sources
Methodology for the Isolation and Analysis of CTCs
2020The majority of deaths related to breast cancer are caused by metastasis. Understanding the process of metastasis is key to achieve a reduction on breast cancer mortality. Currently, liquid biopsies are gaining attention in this regard. Circulating tumor cells (CTCs), an important component of liquid biopsies, are cells shed from primary tumor that ...
Clotilde, Costa, Ana B, Dávila-Ibáñez
openaire +2 more sources