Results 261 to 270 of about 127,497 (313)

A Curcumin‐Derived HSP70 Inhibitor Disrupts Lysosomal Function to Suppress Triple‐Negative Breast Cancer Progression

Cell Proliferation, EarlyView.
Novel curcumin‐derived M4 binds HSP70's ATPase domain, disrupting HSP70‐mediated lysosomes‐autophagy pathway to inhibit TNBC growth and metastasis, and synergizes with paclitaxel for potent combination therapy. ABSTRACT Structural modification of curcumin yielded a novel series of 1,4‐pentadien‐3‐one oxime ether derivatives, among which compound M4 ...
Zijian Li, Wanxia Wang, Yuxin Zhou, Tao Zeng, Jian Liu, Yingjie Qing, Xuan Han   +6 more
wiley   +1 more source

Nitrogen-doped carbon quantum dots as fluorescent sensor for doxorubicin and chlortetracycline: experimental and DFT insights. [PDF]

Nanoscale Adv
Lotfy S, Aboelnga MM, Moawed EA, Elbayoumy E.   +3 more
europepmc   +1 more source

From Tumour to Bloodstream: Advancing PD‐L1 Testing With Liquid Biopsies in Non‐Small Cell Lung Cancer

Cytopathology, EarlyView.
This review explores liquid biopsy as a complementary approach to tissue‐based PD‐L1 assessment in advanced NSCLC treated with immune checkpoint inhibitors. Focusing on circulating tumour cells, extracellular vesicles, and circulating tumour DNA, it summarises current evidence, technical challenges, and future perspectives for personalised ...
R. Leporati, V. Callegari, A. Ancora, M. Palmieri, B. Riccò, E. Cabitza, L. Trudu, K. Di Emidio, C. Chiavelli, A. Eccher, I. Mastrolia, V. Catani, S. Bettelli, G. Guaitoli, M. Dominici, F. Bertolini   +15 more
wiley   +1 more source

Clinical applications and future perspectives of circulating tumor cells in solid tumors. [PDF]

Discov Oncol
Hajizadeh A, Momeni F, Eslami NM, Rajeh SM, Parsian A, Birgani RG, Kananpour N, Pourzare P, Aghili A, Samarjan RS, Ghavamikia N, Shayan SK.   +11 more
europepmc   +1 more source

Socioeconomic status, environmental factors, and motor function in children with cerebral palsy

Developmental Medicine &Child Neurology, EarlyView.
Abstract Aim To investigate the association between socioeconomic status and cerebral palsy (CP) motor function, adjusting for known clinical and candidate environmental risk factors, that is, air pollution and distance to a children's treatment center (CTC).
Hana F Alazem, Ewa Sucha, Richard J Webster, Michelle L Larin, Anna M McCormick, Darcy L Fehlings, CP‐NET Group, Craig Campbell, Jan Willem Gorter, Carolyn Hunt, Anita Jethwa, Anne Kawamura, Marie Kim, Ronit Mesterman, Dawa Samdup   +14 more
wiley   +1 more source

Neurophysiological Basis of Tremor Disorders: Parkinson's Disease, Essential Tremor, Tremor in Dystonia, and Holmes Tremor. [PDF]

Semin Neurol
Wagle Shukla A, Panyakaew P.
europepmc   +1 more source

Liquid biopsy reveals the immune status and protein profiles linked to CTC burden and clinical outcomes in metastatic breast cancer. [PDF]

J Exp Clin Cancer Res
Kurma K, Bardol T, Mollevi C, Eslami-S Z, Garima F, Alexandre M, Bobrie A, Lossaint G, Massemin B, D'Hondt V, Guiu S, Cayrefourcq L, Jacot W, Alix-Panabières C.   +13 more
europepmc   +1 more source

Circulating Tumor Cells: Isolation, Preclinical Models, and Clinical Applications for Personalized Cancer Therapy. [PDF]

Biomolecules
Sisca L, Polito MG, Iuliani M, Papalia GF, Tonini G, Pantano F.   +5 more
europepmc   +1 more source

Health-related quality of life after autologous stem cell transplantation for multiple myeloma or lymphoma impacts professional activity- an analysis from two German tertiary care centers. [PDF]

Front Oncol
Hamm AF, Loesche A, Eisfeld C, Shumilov E, Leitner T, Letsch A, Lenz G, von Bubnoff N, Wenge DV, Khandanpour C.   +9 more
europepmc   +1 more source