Results 161 to 170 of about 39,021 (326)

Harnessing Plasma Biomarkers to Predict Immunotherapy Outcomes in Hepatocellular Carcinoma: The Role of cfDNA, ctDNA, and Cytokines [PDF]

Elena Vargas‐Accarino, Mónica Higuera, María Bermúdez-Ramos, Agnès Soriano-Varela, María Torrens, Mònica Pons, Ana M. Aransay, Jose‐Ezequiel Martín, Francisco Rodríguez-Frías, Xavier Merino, Beatriz Mínguez   +10 more
openalex   +1 more source

Supplemental Figure 1 from Comprehensive ctDNA Measurements Improve Prediction of Clinical Outcomes and Enable Dynamic Tracking of Disease Progression in Advanced Pancreatic Cancer

, 2023
Morten Lapin, Karin H. Edland, Kjersti Tjensvoll, Satu Oltedal, Marie Austdal, Herish Garresori, Yves Rozenholc, Bjørnar Gilje, Oddmund Nordgård   +8 more
openalex   +1 more source

Precision medicine in cutaneous melanoma—A comprehensive review

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Precision medicine tailors treatment to each patient, beginning with detailed diagnostics. In melanoma, it has advanced considerably: Some methods are in practice and guidelines, while others are commercially available but not routine. This review highlights current and emerging approaches, including molecular profiling, imaging, biomarkers and AI ...
Markus Reitmajer, Lukas Flatz
wiley   +1 more source

DNA-Based Liquid Biopsy for Evaluating Surgical and Postsurgical Outcomes in Gynecologic Malignancies: A Systematic Review. [PDF]

J Clin Lab Anal
Liquid biopsy using plasma and uterine aspirate samples provides a minimally invasive tool for detecting and monitoring gynecologic cancers. Circulating tumor DNA (ctDNA) and cell‐free DNA (cfDNA) enable prognosis, treatment response assessment, and improved diagnostic accuracy across various tumor types. ABSTRACT Introduction DNA‐based liquid biopsies,
Yavari S, Javankiani S, Yarahmadi F, Sarallah R, Rezaei B, Maroufi M, Amlashi MK, Imankhan M, Marvi M, Aslani N, Soltanattar A, Mohammadi Z, Azani A, Kavousinia P.   +13 more
europepmc   +2 more sources

Novel Liquid Biopsy in Gastrointestinal Cancers

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Gastrointestinal (GI) cancers represent a significant global health burden, being among the leading causes of cancer‐related deaths. The prognosis for patients remains unsatisfactory, largely because most cancers are detected at advanced stages.
Li‐Chun Chang, Tang‐Long Shen, Takahiro Ochiya   +2 more
wiley   +1 more source

Levels of circulating tumor DNA correlate with tumor volume in gastro‐intestinal stromal tumors: an exploratory long‐term follow‐up study

Molecular Oncology
Patients with gastro‐intestinal stromal tumors (GISTs) undergoing tyrosine kinase inhibitor therapy are monitored with regular computed tomography (CT) scans, exposing patients to cumulative radiation. This exploratory study aimed to evaluate circulating
Roos F. Bleckman, Charlotte M. S. C. Haag, Naomi Rifaela, Gerrieke Beukema, Ron H. J. Mathijssen, Neeltje Steeghs, Hans Gelderblom, Ingrid M. E. Desar, Arjen Cleven, Arja terElst, Ed Schuuring, Anna K. L. Reyners   +11 more
doaj   +1 more source

Revisiting Epidermal Growth Factor Receptor (EGFR) Amplification as a Target for Anti-EGFR Therapy: Analysis of Cell-Free Circulating Tumor DNA in Patients With Advanced Malignancies. [PDF]

, 2019
PurposeTo date, evidence for tissue epidermal growth factor receptor (EGFR) overexpression as a biomarker for anti-EGFR therapies has been weak. We investigated the genomic landscape of EGFR amplification in blood-derived cell-free tumor DNA (cfDNA ...
Fanta, Paul T, Goodman, Aaron, Kato, Shumei, Kurzrock, Razelle, Lanman, Richard B, Lee, Suzanna, Lippman, Scott M, Mareboina, Manvita, Okamura, Ryosuke, Patel, Sandip P, Raymond, Victoria M, Schwab, Richard B, Sicklick, Jason K, Vu, Peter   +13 more
core   +1 more source

ctDNA predicts outcomes in DLBCL [PDF]

Nature Reviews Clinical Oncology, 2018
openaire   +2 more sources

Assessing the exercise‐related kinetics of circulating cell‐free DNA, circulating tumour DNA, DNase I activity and cytokines in patients with solid tumours: A pilot study

Experimental Physiology, EarlyView.
Abstract Circulating cell‐free DNA (cfDNA), circulating tumour DNA (ctDNA) and inflammatory cytokines have prognostic and predictive value in oncology. However, the effects of acute exercise on cfDNA levels are unknown. Here, we explore the kinetics of cfDNA, ctDNA and cytokines upon an incremental exercise test in a pilot cohort of cancer patients ...
Elmo W. I. Neuberger, Alexandra Brahmer, Tobias Ehlert, Suzan Botzenhardt, Alfonso De Falco, Birgit Enders, Patricia S. Hähnel, Achim Heintz, Carl C. Schimanski, Thomas Kindler, Perikles Simon   +10 more
wiley   +1 more source

Supplementary Figure from Persistence of ctDNA in Patients with Breast Cancer During Neoadjuvant Treatment Is a Significant Predictor of Poor Tumor Response

, 2023
Qing Zhou, Simon Peter Gampenrieder, Sophie Frantal, Gabriel Rinnerthaler, Christian F. Singer, Daniel Egle, Georg Pfeiler, Rupert Bartsch, Viktor Wette, Angelika Pichler, Edgar Petru, Peter Dubsky, Zsuzsanna Bagó-Horváth, Christian Fesl, Margaretha Rudas, Anders Ståhlberg, Ricarda Graf, Sabrina Weber, Nadia Dandachi, Martin Filipits, Michael Gnant, Marija Balić, Ellen Heitzer   +22 more
openalex   +1 more source