Results 161 to 170 of about 47,434 (363)
Advances in Laboratory MedicineEl análisis molecular del gen receptor del factor de crecimiento epidérmico (EGFR) resulta fundamental a la hora de seleccionar una terapia dirigida para el carcinoma pulmonar no microcítico avanzado (CPNM).
Fernández-Galán Esther +1 more
doaj +1 more source
Impact of cytological sampling on EGFR mutation testing in stage III-IV lung adenocarcinoma [PDF]
, 2017 Objectives. There have been advances in the identification and understanding of molecular subsets of lung cancer, defined by specific oncogenic aberrations.
Butler, Rachel +5 more
core +3 more sources
Molecular and Cellular Probes, 2019 We aimed to develop a high-throughput deep DNA sequencing assay of cerebrospinal fluid (CSF) to identify clinically relevant oncogenic mutations that contribute to the development of glioblastoma (GBM) and serve as biomarkers to predict patients' responses to surgery.
Zhenghe Chen +13 more
openaire +3 more sources
International Journal of Cancer, EarlyView.What's New? Chemoradiotherapy is the standard treatment for squamous cell carcinoma of the anus (SCCA). Toxicities linked to chemoradiotherapy, however, can negatively impact the quality of life, and biomarkers to distinguish which patients will benefit from treatment are lacking.
Anne Vittrup Jakobsen +4 more
wiley +1 more source
ctDNA to Predict Treatment Response in Head and Neck Squamous Cell Carcinoma: A Systematic Review
The Laryngoscope, EarlyView.This systematic review aims to investigate the role of plasma circulating tumor DNA in head and neck cancer surveillance. We conducted a systematic review to comprehensively assess the findings and quality of existing literature on this topic. Our findings show that ctDNA monitoring post‐treatment likely has utility in HNSCC surveillance.
Oliver Jones +2 more
wiley +1 more source
Circulating microRNA biomarkers in melanoma: tools and challenges in personalised medicine [PDF]
, 2018 Effective management of melanoma depends heavily on early diagnosis. When detected in early non-metastatic stages, melanoma is almost 100% curable by surgical resection, however when detected in late metastatic stages III and IV, 5-year survival rates ...
Gilleard, Onur +5 more
core +2 more sources
Exploring the biology of ctDNA release in colorectal cancer
European Journal of CancerCirculating tumor DNA (ctDNA) has emerged as a promising tool for early cancer detection and minimal residual disease monitoring. However, the biology underlying ctDNA release and its variation across cancer types and histologies remains poorly understood. This study investigated the biology behind ctDNA shedding in colorectal cancer.The study included
Andersen, Laura +8 more
openaire +3 more sources
Rad51 at the Crossroads: Bridging DNA Repair, Tumorigenesis, and Immune Regulation
Med Research, EarlyView.Therapeutic landscape of Rad51 in cancer treatment. Key elements include (1) DNA damage sources (PARPi, chemo/radiotherapy); (2) repair pathways (Rad51‐mediated HR); (3) intervention strategies (Rad51 inhibitors, CRISPR/Cas9); and (4) combination approaches (immunotherapy). The figure is created with BioRender.com.
Zhendong Qin +4 more
wiley +1 more source
Российский офтальмологический журналPurpose: to analyze the frequency of GNAQ/GNA11 mutations in circulating tumor DNA and tumor tissue, and the frequency of genotypes of polymorphic marker C3435T of ABCB1 gene in patients with iris melanoma. Material and methods.
S. V. Saakyan +4 more
doaj +1 more source
Plasma ctDNA for the detection of EGFR mutation status in advanced nsclc (aNSCLC) as per local diagnostic practices: Japanese subset data from assess [PDF]
, 2016 Takashi Yokoi +7 more
openalex +1 more source