Results 191 to 200 of about 39,021 (326)

Biomarker analysis of circulating tumor DNA in clinical stage III melanoma patients treated with neoadjuvant immunotherapy combined with targeted therapy. [PDF]

Ther Adv Med Oncol
Stoff R, Routman DM, Yalon M, Bogan AW, Block MS, Hieken TJ.   +5 more
europepmc   +1 more source

Emerging Role of ctDNA Fragmentomics and Epigenetic Signatures in the Early Detection, Minimal Residual Disease Assessment, and Precision Monitoring of Renal Cell Carcinoma

Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.
ABSTRACT Renal cell carcinoma (RCC) presents a significant global health challenge, with a substantial proportion of patients diagnosed with advanced or metastatic disease due to the limitations of current diagnostic imaging and the lack of validated non‐invasive biomarkers.
Hossam Kamli, Najeeb Ullah Khan
wiley   +1 more source

The role of circulating tumor DNA in gynecological cancer management. [PDF]

Front Oncol
Gao M, Yu PY, Li RX, Chen C, Cong XF, Liu ZL.   +5 more
europepmc   +1 more source

Epigenomics‐guided precision oncology: Chromatin variants in prostate tumor evolution

International Journal of Cancer, Volume 158, Issue 2, Page 314-332, 15 January 2026.
Abstract Prostate cancer is a common malignancy that in 5%–30% leads to treatment‐resistant and highly aggressive disease. Metastasis‐potential and treatment‐resistance is thought to rely on increased plasticity of the cancer cells—a mechanism whereby cancer cells alter their identity to adapt to changing environments or therapeutic pressures to create
Kira Furlano, Tina Keshavarzian, Nadine Biernath, Annika Fendler, Maria de Santis, Joachim Weischenfeldt, Mathieu Lupien   +6 more
wiley   +1 more source

Liquid biopsy: a step forward in laboratory medicine

Advances in Laboratory Medicine
Díaz-Lagares Angel, Jiménez Wladimiro
doaj   +1 more source

Clinical utility of longitudinal ctDNA monitoring by multiplex MS-ddPCR for risk stratification and follow-up in rectal cancer. [PDF]

Int J Colorectal Dis
Lauridsen ED, Do Canto LM, Timm S, Havelund BM, Lindebjerg J, Jensen LH, Andersen RF, Hansen TF.   +7 more
europepmc   +1 more source

Aptamer‐Engineered Ellipsometry for Clinical Detection of BALF‐Derived Exosomes: Multi‐Level Engineering for Prognostic Evaluation of Immunotherapy Responses

Advanced Science, Volume 13, Issue 3, 14 January 2026.
A novel ellipsometry platform functionalized with truncated PD‐L1 aptamers are developed to enable ultrasensitive detection of BALF‐derived exosomes. Through chemical ligand tailoring, mechanical sensing optimization, and tumor‐proximal fluid sampling, the system precisely stratifies ICI responders and non‐responders, offering superior sensitivity and ...
Euna Jeong, Jung Hyun Choi, Minyoung Lee, Jun Hyeok Lim, Seokho Jung, Yeeun Woo, Joo‐young Kim, Jaehyeon Ok, Lucia Kim, Woo‐jin Jeong, Won Chegal, Hyun Mo Cho, Chulhwan Park, Jiyoon Bu, Dong Hyung Kim, Taek Lee   +15 more
wiley   +1 more source

ctDNA Detected after Neoadjuvant Therapy for HER2-Positive Breast Cancer Is Associated with Inferior Outcomes and May Inform Adjuvant Therapy. [PDF]

Cancer Res Commun
Lin PH, Tsai LW, Lo C, Kuo SH, Ni CC, Yu CH, Huang CS.   +6 more
europepmc   +1 more source

Breaking the ctDNA sensitivity barrier

, 2017
O estudo da biologia molecular do cancro tem permitido avanços científicos com impacto na prática clínica, mudando o paradigma de abordagem terapêutica convencional, sistémica, para uma abordagem personalizada. No entanto, a caracterização molecular de tumores sólidos só é possível através da biopsia do tecido, uma estratégia altamente invasiva com ...
openaire   +1 more source

Integrating Immune Checkpoint Inhibitors With Total Neoadjuvant Therapy in Proficient Mismatch Repair Rectal Cancer

Annals of Gastroenterological Surgery, Volume 10, Issue 1, Page 145-153, January 2026.
The key to unlocking ICI benefit in pMMR/MSS LARC is to convert “cold” tumors into “hot” ones through lymphocyte‐sparing SCRT and judicious chemotherapy, creating a milieu in which ICIs can act effectively. ABSTRACT The management of locally advanced rectal cancer (LARC) has evolved with the adoption of total neoadjuvant therapy (TNT), integrated ...
Yoshinori Kagawa, Jun Watanabe, Koji Ando, Caleah Kitchens, Aron Bercz, J. Joshua Smith   +5 more
wiley   +1 more source