Results 191 to 200 of about 47,434 (363)

USP44, ZNF454, and GPRC5B ctDNA Methylation Markers in Breast Cancer: Limited Clinical Relevance for Disease Monitoring and Tumor Characteristics

open access: yesAsia-Pacific Journal of Clinical Oncology, EarlyView.
We selected breast cancer‐specific DNA methylation markers using The Cancer Genome Atlas (TCGA). We analyzed the methylation and expression patterns of candidate genes in breast cancer cell lines, ctDNA, and tissue samples. The relationship between ctDNA methylation markers and the clinicopathological features of breast cancer patients was investigated.
Young Ju Jeong   +6 more
wiley   +1 more source

El papel de la enfermería en la Biopsia Líquida [PDF]

open access: yes, 2019
Introducción: El cáncer sigue constituyendo una de las principales causas de morbilidad del mundo. Las estimaciones poblacionales indican que el número de casos probablemente aumente a un 70% en las próximas décadas. Desde el año 2000 en nuestro país, el
Villaverde Hueso, María
core  

The effects of LIPUS on ctDNA release in the medium of NSCLC cell lines [PDF]

open access: bronze, 2017
Alessandro Perez   +18 more
openalex   +1 more source

Ultrasensitive ctDNA detection for preoperative disease stratification in early-stage lung adenocarcinoma

open access: yesNature Network Boston
Circulating tumor DNA (ctDNA) detection can predict clinical risk in early-stage tumors. However, clinical applications are constrained by the sensitivity of clinically validated ctDNA detection approaches.
James R. M. Black   +35 more
semanticscholar   +1 more source

Circulating tumour DNA as a predictor of survival of patients with diffuse large B‐cell lymphoma in a daily practice

open access: yesBritish Journal of Haematology, EarlyView.
Circulating tumour DNA (ctDNA) is a promising biomarker for diffuse large B‐cell lymphoma (DLBCL) risk stratification and treatment response assessment, but real‐world studies were limited. Using a targeted sequencing approach (521‐gene panel), we showed that (1) baseline ctDNA level correlated with tumour burden and was an independent predictor of ...
Prokop Vodicka   +21 more
wiley   +1 more source

Genomic profiling for advanced non-small-cell lung cancer (NSCLC) from circulating tumour DNA (ctDNA) [PDF]

open access: bronze, 2017
Herbert H. Loong   +7 more
openalex   +1 more source

DNA Methylation in Ovarian and Endometrial Cancers: Predictive and Mechanistic Roles in PARP Inhibitor and ICI Response

open access: yesCancer Science, EarlyView.
Cancer treatment is shifting from an organ‐based framework to one driven by biological phenotypes, and DNA methylation is increasingly recognized as an important factor that governs tumor behavior beyond genetic mutations. In gynecologic cancers, BRCA1 and MLH1 promoter methylation–associated homologous recombination deficiency and mismatch repair ...
Shuhei Kitamura   +12 more
wiley   +1 more source

Plasma EGFR mutation ctDNA dynamics in patients with advanced EGFR-mutated NSCLC treated with Icotinib: phase 2 multicenter trial result

open access: yesScientific Reports
Plasma epidermal growth factor receptor mutation (EGFRm) circulating tumor DNA (ctDNA) dynamics exhibit promise in predicting outcomes in patients with EGFRm-advanced non-small cell lung cancer (NSCLC).
Yaping Hong   +12 more
doaj   +1 more source

Systemic Surveillance Guidelines for Uveal Melanoma: A Systematic Review

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background Uveal melanoma (UM) is the most common primary intraocular tumour. Despite effective local therapies, UM has a high risk of metastatic recurrence, most frequently to the liver. A significant proportion of patients treated definitively for primary UM eventually experience metastatic disease. Systemic surveillance to detect recurrence
Farzana Y. Zaman   +6 more
wiley   +1 more source

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