Results 81 to 90 of about 2,662 (167)

Single-cell and transcriptome analyses revealed CTHRC1 a potential therapeutic target mediating invasion and tumor microenvironment in TNBC: experimental validation

Frontiers in Immunology
BackgroundInvestigating the pivotal role of CTHRC1 in the tumor microenvironment of triple-negative breast cancer (TNBC).MethodThe RNA transcriptomic data obtained from the Cancer Genome Atlas and single-cell sequencing data from TNBC in Gene Expression ...
Hong Wan, Hong Wan, Zichen Ling, Zichen Ling, Yuwei Xie, Yuwei Xie, Han Jiang, Han Jiang, Zhifan Ruan, Zhifan Ruan, Dashuai Yang, Xiaowei Yang, Xiaowei Yang, Jing Pei, Jing Pei   +14 more
doaj   +1 more source

CTHRC1 is a prognostic biomarker correlated with immune infiltration in head and neck squamous cell carcinoma

BMC Oral Health
Background Head and neck squamous cell carcinoma (HNSCC) is the sixth most common malignancy worldwide, characterized by high morbidity, high mortality, and poor prognosis.
Zhichao Zhang, Xusheng Ren, Yiling Wang, Ping Liu, Peng Lin, Shumei Jin, Chao Xu   +6 more
doaj   +1 more source

CTHRC1 drives megakaryocyte-mediated immunotherapy resistance in esophageal squamous cell carcinoma via the integrin αIIbβ3/Rap1 pathway and is targetable by mRNA vaccination

Molecular Cancer
The clinical efficacy of immunotherapy in advanced esophageal squamous cell carcinoma (ESCC) remains suboptimal, as most patients eventually develop drug resistance and experience disease progression.
Yixin Liu, Jianfeng Zhou, Mengyuan Song, Jian Wang, Qixin Shang, Jiajia Du, Yanxin Li, Xiangzheng Chen, Jing Wang, Xuerui Liao, Longqi Chen, Weimin Li, Yong Yuan, Yushang Yang, Yangping Wu   +14 more
doaj   +1 more source

CTHRC1 Gene [PDF]

, 2020
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Circulating CTHRC1 Levels are Associated with IPF Disease Severity and Survival

Thorax
Abstract Objective Idiopathic pulmonary fibrosis (IPF) is a disease of high morbidity and mortality. We previously identified a novel subset of pathologic fibroblasts, characterized by CTHRC1 expression, uniquely present in fibrotic lung diseases.
Monica M Yang, Tatsuya Tsukui, Michael Wax, Seoyeon Lee, Averey Lea, Alexey Bazarov, Lisa Hazelwood, Paul J Wolters, Dean Sheppard   +8 more
openaire   +1 more source

CTHRC1 wt Allele [PDF]

, 2020
openaire   +1 more source

Evaluation of Collagen Triple Helix Repeat Containing-1 protein in Postmenopausal Women with Osteoporosis

مجله كليه طب الكندي
Background: The collagen triple helix repeat containing 1 (CTHRC1) protein has been connected to decreased levels of vitamin D and calcium, as well as obesity.
Isam Salman , Noor Ulhuda Mohammed, Rand Jalal Abd Al-Ghanny, Baydaa Abed, Samara mutar   +4 more
doaj   +1 more source

CTHRC1 is associated with BRAF(V600E) mutation and correlates with prognosis, immune cell infiltration, and drug resistance in colon cancer, thyroid cancer, and melanoma

Biomolecules & Biomedicine
Colon cancer, thyroid cancer, and melanoma are common malignant tumors that seriously threaten human health globally. The B-Raf proto-oncogene, serine/threonine kinase (BRAF)(V600E) mutation is an important driver gene mutation in these cancer types. In
Rumeng Zhang, Zhihao Wang, Huan Wang, Lin Li, Lin Dong, Lin Ding, Qiushuang Li, Linyan Zhu, Tiantian Zhang, Yong Zhu, Keshuo Ding   +10 more
doaj   +1 more source

Research Progress of CTHRC1 in the Organ Fibrosis

Advances in Clinical Medicine, 2023
openaire   +1 more source

LRP1 activated by AT2 cell-secreted MDK inhibits fibrotic ferroptosis in idiopathic pulmonary fibrosis. [PDF]

iScience
Hua W, Wang Z, Dai Z, Zhang Z, Li X, Wu B, Huang M, Chen J.   +7 more
europepmc   +1 more source