Results 61 to 70 of about 3,210 (194)

Estimation levels of CTHRC1and some cytokines in Iraqi patients with Rheumatoid Arthritis

مجلة بغداد للعلوم, 2023
Collagen triple helix repeat containing-1 (CTHRC1) is an essential marker for Rheumatoid Arthritis (RA), but its relationship with pro-inflammatory, anti-inflammatory, and inflammatory markers has been scantily covered in extant literature.
Ahmed R. Oleiwi, Ayaid Khadem Zgair
doaj   +1 more source

Periodontitis and metabolic dysfunction‐associated steatotic liver disease

Periodontology 2000, EarlyView.
Abstract Objective Periodontitis is a chronic inflammatory disease with systemic effects that extend beyond the oral cavity and contribute to systemic immune and metabolic dysregulation. Chronic liver diseases, particularly metabolic dysfunction‐associated steatotic liver disease (MASLD) and its progressive phenotypes, have emerged as major global ...
Rafael Scaf de Molon, Erica Dorigatti de Avila, Davi da Silva Barbirato, Mariana Fampa Fogacci, Jamil Awad Shibli, Anton Sculean, Alpdogan Kantarci   +6 more
wiley   +1 more source

Non‐invasive biomarkers in biliary atresia: A scoping review of fibrosis assessment, translational readiness and clinical implementation gaps

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
Biomarkers are positioned by their highest developmental stage. Most biomarkers remain in exploratory phases, with serum MMP‐7 and elastography showing the greatest translational maturity. This highlights the primary challenge is the transition from biomarker discovery to clinical implementation.
Elizabeth Brits, Stephen Brown, Lezelle Botes, Michael Pienaar   +3 more
wiley   +1 more source

Overexpression of CTHRC1 in HCC.

, 2013
(A) RT-PCR analysis showed overexpression of CTHRC1 in 4 of 8 HCC specimens (T), but in none of the 8 specimens of nontumorous liver parenchyma (N). S26 (ribosomal protein S26) served as internal control.
Yu-Ling Chen (399126), Hey-Chi Hsu (52813), Yung-Ming Jeng (197758), Ting-Huang Wang (439324), Ray-Hwang Yuan (399127)   +4 more
core   +1 more source

Perivascular Matrix Densification Dysregulates Angiogenesis and Activates Pro‐Inflammatory Endothelial Cells

Advanced Science, Volume 13, Issue 49, 3 September 2026.
Perivascular matrix densification promotes the emergence of aberrant endothelial tip cells (ATECs) that invade and persist within fibrotic microenvironments. Using in vivo lineage tracing and a human microvessel model, this study shows that fibrous matrix cues destabilize VE‐cadherin–mediated junctions to gate TGF‐β signaling, inducing a pro ...
Jingyi Xia, William Y. Wang, Kyle A. Jacobs, Kairav Maniar, Daphne Lin, Evan H. Jarman, Daniel L. Matera, Kristen Loesel, Christopher D. Davidson, Harrison L. Hiraki, Xiaotian Tan, Eve H. Shikanov, Robert N. Kent, Carole Parent, Xudong Fan, Ariella Shikanov, Matthew L. Kutys, Brendon M. Baker   +17 more
wiley   +1 more source

Cthrc1 localizes to the pituitary gland.

, 2014
Immunolocalization of Cthrc1 in human pituitary glands identifies cells expressing Cthrc1 in the anterior lobe (A, arrow). (B, C) Accumulations of colloid-like material contain Cthrc1 immunoreactivity.
Qiaozeng Wang (303995), Ivette F. Emery (580176), Andrew Prueser (580177), J. Patrizia Stohn (303993), Christine W. Duarte (189868), Volkhard Lindner (303997)   +5 more
core   +1 more source

CTHRC1 May Serve As A Prognostic Biomarker For Hepatocellular Carcinoma.

OncoTargets and therapy, 2019
Hepatocellular carcinoma is a common malignant cancer and the second most common cause of cancer-related deaths worldwide. Collagen triple helix repeat containing 1 (CTHRC1) has been increasingly reported to be involved in tumorigenesis and/or tumor progression.
Zhou,Huifang, Su,Libo, Liu,Chao, Li,Baosheng, Li,Hui, Xie,Ying, Sun,Dianxing   +6 more
openaire   +3 more sources

Organelle Crosstalk and Metabolic Reprogramming in Idiopathic Pulmonary Fibrosis: Mechanisms and Therapeutic Implications

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease of unknown cause, marked by excessive deposition of extracellular matrix (ECM) components such as collagen. This pathological accumulation results in progressive destruction of the lung architecture and ultimately leads to respiratory failure.
Yining Zhang, Ling Teng, Limin Gong, Yuandong Fu, Minyi Qian   +4 more
wiley   +1 more source

Mouse transgenic model of Cthrc1 overexpression.

, 2014
Cthrc1 protein was assessed by immunohistochemistry in bi-transgenic Tg(CagGfp-hCthrc1)Vli/ Tg(Pdgfrb-Cre)35Vli mice. (A) Skeletal muscle, (B) capillaries in brown adipose tissue, (C) hepatic endothelium, (D) vascular smooth muscle in the kidney, and (E)
Qiaozeng Wang (303995), Ivette F. Emery (580176), Andrew Prueser (580177), J. Patrizia Stohn (303993), Christine W. Duarte (189868), Volkhard Lindner (303997)   +5 more
core   +1 more source

Collagen triple helix repeat containing-1 negatively regulated by microRNA-30c promotes cell proliferation and metastasis and indicates poor prognosis in breast cancer

Journal of Experimental & Clinical Cancer Research, 2017
Background Collagen triple helix repeat containing-1 (CTHRC1), which was firstly identified overexpressed in the adventitia and neointima of injured rat arteries, could inhibit collagen expression and increase cell migration.
Yuan-hui Lai, Jian Chen, Xiao-ping Wang, Yan-qing Wu, Hai-tao Peng, Xiao-hong Lin, Wen-jian Wang   +6 more
doaj   +1 more source