Results 91 to 100 of about 329,027 (236)
Arming CTLs against immunosuppressors
Blood, 2009 Cell therapy efficacy after organ transplantation is hampered by the detrimental effects of pharmacologic immunosuppression on T-cell expansion and function. In this issue of Blood , 2 independent groups describe genetic engineering of ex vivo expanded EBV-CTLs to induce calcineurin-inhibitor resistance.
openaire +4 more sources
Novel Bivalent mRNA‐LNP Vaccine for Highly Effective Protection against Pneumonic Plague
Advanced Science, EarlyView.The study investigates mRNA‐lipid nanoparticle vaccines targeting Yersinia pestis, the causative agent of plague. Combined F1+LcrV mRNA vaccination elicited robust immune responses and protected mice against virulent wild‐type and atypical strains.
Uri Elia +12 more
wiley +1 more source
Advanced Science, EarlyView.Herein, waste fluororubbers undergo controlled oxidative degradation induced by alkali and hydrogen peroxide to yield carboxyl terminated liquid fluororubbers. Subsequently, condensation reaction system efficiently converts carboxyl groups into photoreactive vinyl groups.
Donghan Li +12 more
wiley +1 more source
, 2007 Hybrid branching-time logics are introduced as extensions of CTL-like logics with state variables and the downarrow-binder. Following recent work in the linear framework, only logics with a single variable are considered.
Weber, Volker
core +1 more source
Advanced Science, EarlyView.Y332D, a bispecific antibody that simultaneously blockades VEGF and TGF‐β, counteracted negative RT effects that are attributed to the upregulation of TGF‐β and VEGF, as well as further enhanced the immunostimulatory effects of RT, thereby reprograming the TME from immune “cold” to inflamed state and forming an effective in‐situ vaccine that eradicate ...
Lijuan Lyu +13 more
wiley +1 more source
Advanced Science, EarlyView.Schematic model of CJP–TiN liposomes for gastric cancer (GC) treatment. Internalizing RGD peptide (iRGD) targets tumor cells, while Chlorin e6 (Ce6) generates reactive oxygen species (ROS). Jolkinolide B (JB) activates the PANoptosis pathway via caspase‐8, enhancing GC cell death and immune response, transforming “cold tumors” into “hot tumors” by ...
Chenhui Ma +14 more
wiley +1 more source
Host immune response to cytomegalovirus [PDF]
, 1987 To confirm that immediate-early (IE) genes of murine cytomegalovirus (MCMV) give rise to antigens recognized by specific cytolytic T lymphocytes (CTL), a 10.8-kilobase fragment of MCMV DNA which is abundantly transcribed at IE times was transfected into ...
Keil, Günther M. +3 more
core
Advanced Science, EarlyView.A schematic illustration of the cyanobacteria‐based biohybrid platform for photodynamic cancer therapy enhanced PDT. The platform continuously outputs O2 (to alleviate tumor hypoxia) and 1O2 (for tumor treatment), achieving improved photodynamic immunotherapy. Abstract The interdisciplinary development of synthetic biology and material sciences propels
Zhengwei Xu +14 more
wiley +1 more source
, 2010 Occasional information sheet; dates included are: Jan. 15; Feb. 1; Mar.
Staff, CTL
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