ISIT-GEN: An in silico imaging trial to assess the inter-scanner generalizability of CTLESS for myocardial perfusion SPECT on defect-detection task [PDF]
arXivA recently proposed scatter-window and deep learning-based attenuation compensation (AC) method for myocardial perfusion imaging (MPI) by single-photon emission computed tomography (SPECT), namely CTLESS, demonstrated promising performance on the clinical task of myocardial perfusion defect detection with retrospective data acquired on SPECT scanners ...
arxiv
Blocking of CTL-mediated killing by monoclonal antibodies to LFA-1 and LYT-2,3. I. Increased susceptibility to blocking after papain treatment of target cells. [PDF]
, 1983 S H Gromkowski +4 more
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Advanced Science, EarlyView.This study discovers that SIRT1, a hub gene involved in glucolipid metabolic conversion in colorectal carcinoma (CRC), stimulates CX3CL1 secretion in CRC cells by activating FOXO1. The CX3CL1‐CX3CR1 signaling promotes the differentiation of TCF7+ regulatory T cells (Tregs) into an enhanced immunosuppressive TNFRSF9+ Treg phenotype.
Ruiyang Zi +18 more
wiley +1 more source
Immunological and prognostic significance of novel ferroptosis-related genes in soft tissue sarcoma
PLoS ONE, 2022 Background Ferroptosis has exhibited great potential in the treatment of cancer and has gained widespread attention in soft tissue sarcoma (STS). The aim was to explore the immunological and prognostic significance of novel ferroptosis-related genes in ...
Jiazheng Zhao +4 more
doaj
Human alloreactive CTL clones: loss and reacquisition of specific cytolytic activity can be regulated by "recombinant" interleukin 2. [PDF]
, 1985 S L Wee, A C Ochoa, F H Bach
openalex +1 more source
Advanced Science, EarlyView.An unprecedented high‐resolution spatial atlas of the E. multilocularis infection foci is obtained, revealing the dynamic functions of neutrophils, Spp1+ macrophages, and fibroblasts during disease progression. The transition of parasite control strategy from “active killing” to “negative segregation” by the host may provide instructive insights into ...
Zhihua Ou +35 more
wiley +1 more source
CTL* Verification and Synthesis using Existential Horn Clauses [PDF]
arXivThis work proposes a novel approach for automatic verification and synthesis of infinite-state reactive programs with respect to ${CTL}^*$ specifications, based on translation to Existential Horn Clauses (EHCs). $CTL^*$ is a powerful temporal logic, which subsumes the temporal logics LTL and CTL, both widely used in specification, verification, and ...
arxiv
In vivo priming of mouse CTL precursors directed to product of a newly defined minor H-42 locus is under a novel control of class II MHC gene. [PDF]
, 1985 Hiromichi Ishikawa +4 more
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Targeting KMT5C Suppresses Lung Cancer Progression and Enhances the Efficacy of Immunotherapy
Advanced Science, EarlyView.This study reveals that KMT5C activates DNA damage repair to inhibit STING‐IRF3 pathway, downstream type I IFN signaling and CCL5 secretion, leading to the downregulation of CD8+ T cell infiltration and function in NSCLC, ultimately facilitating tumor progression.
Yunfeng Yuan +11 more
wiley +1 more source
A "nonidiotypic" inhibition of influenza-immune H-2-restricted CTL by an anti-T cell serum. [PDF]
, 1980 Rita B. Effros +2 more
openalex +1 more source