Results 191 to 200 of about 329,027 (236)

Illuminating Immunity: A Systematic Review of Immune Cell Autofluorescence

Journal of Biophotonics, EarlyView.
ABSTRACT Immunophenotyping provides valuable prognostic and diagnostic information, but is technically complex and expensive. The assessment of autofluorescence is label‐free and provides complex information on cell identity. However, research on its application to immunophenotyping has been heterogenous.
Aline Knab, Caroline Giardina, Shane T. Grey, Ewa M. Goldys, Jared M. Campbell   +4 more
wiley   +1 more source

Cbl-b inhibitor NX-1607 activates MAPK/ERK signaling pathway and enhances T-cell activation. [PDF]

J Immunother Cancer
Zhu W, Lu S, Jia L, Liu B, Song S, Bao X, Yu T, Zhang Y, Miao Z, He J.   +9 more
europepmc   +1 more source

Carbon‐ion irradiation together with autophagy inhibition and immune checkpoint inhibitors protect against pancreatic cancer development in mouse model

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
Abstract Background Pancreatic cancer remains fatal because of resistance to chemo‐, radio‐, and immunotherapies. Carbon‐ion radiotherapy (CIRT) has been beneficial for patients with pancreatic cancer. The purpose of this study was to identify the mechanism by which CIRT exerts its anticancer activity, particularly in combination with immunotherapy ...
Makoto Sudo, Yaoyao Wang, Jingren Wang, Koubun Yasuda, Keiko Mitani, Shuhei Hayashi, Masaki Ohmuraya, Hiroko Tsutsui, Jiro Fujimoto   +8 more
wiley   +1 more source

Super-high tumor mutational burden predicts complete remission following immunotherapy: from Peto's paradox to druggable cancer hallmark. [PDF]

J Immunother Cancer
Zheng M.
europepmc   +1 more source

Trends in Immunotherapy (IO) Use and Survival Among Patients With High‐Incidence Stage IV Cancers Across the United States

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives IO has transformed cancer management, but its adoption in advanced cancer patients varies by tumor type. With more Stage IV patients undergoing surgery, understanding site‐specific outcomes in these challenging patients is essential.
Samantha C. Warwar, Lauren M. Janczewski, Gladys M. Rodriguez, Jeffrey D. Wayne, David J. Bentrem   +4 more
wiley   +1 more source

Multifaceted regulatory mechanisms of the EGR family in tumours and prospects for therapeutic applications (Review). [PDF]

Int J Mol Med
Guo R, Wang R, Zhang W, Li Y, Wang Y, Wang H, Li X, Song J.   +7 more
europepmc   +1 more source

Human microbiota influence the immune cell composition and gene expression in the tumor environment of a murine model of glioma. [PDF]

Gut Microbes
Green GBH, Cox-Holmes AN, Marlow GH, Potier ACE, Wang Y, Zhou L, Chen D, Morrow CD, McFarland BC.   +8 more
europepmc   +1 more source

IFN-α and vitamin B6-induced galectin-9 promotes the immunomodulatory function of human clonal mesenchymal stem cells. [PDF]

Stem Cell Res Ther
Nam JH, Moon JH, Choi B, Kang GH, Park Y, Park SY, Ko TH, Shin D, Jung Y, Kim SN, Cho YK, Jeon MS.   +11 more
europepmc   +1 more source