Results 271 to 280 of about 180,278 (321)

Advancements in the Application of the Intersection of Medicine and Engineering in Cancer Research

Cancer Nexus, EarlyView.
ABSTRACT Cancer research predominantly centers on diagnosis, treatment, and elucidation of underlying mechanisms. Nevertheless, the intricate nature of tumor genesis and development has rendered early diagnostic and therapeutic outcomes less than optimal, making tumor conquest a formidable challenge.
Haitao Chen, Guanmeng Zhang, Yuping Qian, Yang Peng, Xiaoli Li, Jiawen Wang, Jinlan Wang, Yuxiang Hu, Han Xiao, Qinqiu Zhong, Xin Li, Yumeng Xie, Yukun Chen, Lijun Zhao, Qiqi Jing, Xiaofeng Shan, Yuguang Wang   +16 more
wiley   +1 more source

Establishment of a Prognostic Risk Score Model Based on Bioinformatics for Ferroptosis and Cuproptosis‐Related Genes in Gastric Cancer

Cancer Nexus, EarlyView.
ABSTRACT Background Gastric cancer (GC) stands out as one of the most prevalent forms of malignant tumors globally, characterized by a notably high mortality rate. In spite of progress in medical science and treatment alternatives, the survival rate over 5 years continues to stay under 40%.
Yang Shaokang, Yang Peng, Liu Zhicheng, Chen Yujia, He Qitong, Wang Daguang   +5 more
wiley   +1 more source

Single cell transcriptome sequencing indicates the cellular heterogeneity of small intestine tissue in celiac disease. [PDF]

Sci Rep
Shi T, Feng Y, Ma J, Liu W, Li N, Li T, Abudurexiti A, Tuerxuntayi A, Xue S, Gao F.   +9 more
europepmc   +1 more source

Enzymatic Treatment of Lignin in Alkaline Homogeneous Systems: A Review on Alkaliphilic Laccases

ChemSusChem, EarlyView.
This review summarizes the enzymatic treatment of lignin in alkaline homogeneous systems, with a focus on alkaliphilic laccases. Unlike native laccases that promote lignin polymerization under acidic conditions, these enzymes work in basic pH, where industrial lignins are soluble.
Lou Delugeau, Stéphane Grelier, Frédéric Peruch   +2 more
wiley   +1 more source

CDC25A inhibition sensitizes melanoma cells to doxorubicin and NK cell therapy. [PDF]

Cell Death Dis
Gao X, Liu F, Zhang B, Ren T, Zheng Y, Niu Z, Ren H, Liu C, Jiang C, Wang C, Huang H, Ma L, Sun Q.   +12 more
europepmc   +1 more source

OMIP‐113: Characterization of Cytokine Producing T Cells in Swine

Cytometry Part A, EarlyView.
ABSTRACT T cells are essential for preventing diseases and providing long‐term protective immunity. The functional capacity of T cells and the quality of their responses to antigens can be measured by the cytokines they produce. We developed a conventional flow cytometry panel utilizing commercially available antibodies to measure antigen‐specific T ...
Riccardo Arrigucci, Abby Patterson, Chloe Brown, Peter Dube   +3 more
wiley   +1 more source

A multi-institutional cohort study on risk of sleep disorders in dry eyes patients using TriNetX. [PDF]

Sci Rep
Wu BQ, Kuo HT, Hsu AY, Shao YC, Hsia NY, Lai CT, Tseng H, Chiang CC, Lin CJ, Chen HS, Wang YH, Tsai YY, Hsu MY, Cheng-Chung Wei J.   +13 more
europepmc   +1 more source

Longitudinal monitoring of class‐switched memory‐B cell proportions identifies plausible germinal center failure in patients with suspected immune disorders

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract A reduced proportion of peripheral class‐switched memory B cells (CSM‐B cells) is presumed to indicate ineffective germinal activity. The extent that this finding corresponds to a plausible germinal center failure pathophysiology in patients not diagnosed with CVID or hyper IgM syndrome is not known.
Vijaya Knight, Olivia Starich, Cullen M. Dutmer, Jordan K. Abbott   +3 more
wiley   +1 more source

The association of albumin-corrected anion gap and acute kidney injury in heart failure patients: a competing risk model analysis. [PDF]

BMC Cardiovasc Disord
Ruan AF, Zheng JW, Sun SQ, Liu XZ, Chen TL.   +4 more
europepmc   +1 more source

Immune Checkpoint Inhibitors and Cardiovascular Adverse Events

ESC Heart Failure, EarlyView.
Abstract In the last years, we assisted to a tremendous increase in therapeutic options for the management of cancers, with immunotherapy at the forefront of this innovation. Immune checkpoint inhibitors (ICIs) have been developed to enhance the activity of the immune system against cancer cells (1) and the number of approvals for ICIs has rapidly ...
Maria Luisa De Perna, Elia Rigamonti, Raffaele Zannoni, Vittoria Espeli, Giorgio Moschovitis   +4 more
wiley   +1 more source