Results 271 to 280 of about 436,571 (380)

Partial Agonist Effect Influences the CTL Response to a Heterologous Dengue Virus Serotype [PDF]

, 1999
J Zivný, Matthew C. DeFronzo, William Jarry, Julie Jameson, John Cruz, Francis A. Ennis, Alan L. Rothman   +6 more
openalex   +1 more source

Treg Cells Modulate Neuroinflammation and Behavioral Deficits in Autism: Evidence From MR‐Based Genetic Analyses and Experimental Models

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental condition that is increasingly linked to immune dysfunction and neuroinflammation. Regulatory T cells (Tregs), which are crucial in maintaining immune homeostasis, have been implicated in the pathogenesis of ASD.
Zuqing Nie, Xinyi Xu, Junhao Chen, Huiling Chen, Meng Li, Yang Zhang, Zhiwei Li, Chen Shen, Jie Wen, Xia Cao   +9 more
wiley   +1 more source

VRK2 targeting potentiates anti-PD-1 immunotherapy in hepatocellular carcinoma through MYC destabilization. [PDF]

Nat Commun
Su C, Liao Z, Mo J, Liu F, Wang W, Zhang H, Zhang H, Liu Y, Pan Y, Zhu H, Chen X, Zhang Z, Zhu P, Zhang B.   +13 more
europepmc   +1 more source

CTL responses induced by a single immunization with peptide encapsulated in biodegradable microparticles

, 1997
Charalambos D. Partidos, P. Vohra, David T. Jones, Graham H. Farrar, Michael Steward   +4 more
openalex   +1 more source

CD86 (B7-2) Can Function to Drive MHC-Restricted Antigen-Specific CTL Responses In Vivo [PDF]

, 1999
Michael G. Agadjanyan, Jong J. Kim, Neil N. Trivedi, Darren M. Wilson, Behjatolah Monzavi‐Karbassi, Lake Morrison, Liesl Nottingham, Tzvete Dentchev, Anthony Tsai, Kesen Dang, Ara A. Chalian, Michael A. Maldonado, William V. Williams, David B. Weiner   +13 more
openalex   +1 more source

Multiple low dose streptozotocin‐induced diabetes as a model for studying autoimmune diabetes in humans

Animal Models and Experimental Medicine, EarlyView.
Multiple low dose streptozotocin‐induced diabetes is a valuable animal model of diabetes type 1. It should be improved by further research on autoantigens, microbiota and mucosal immune cells from the gut, but also from other organs. Abstract The autoimmune response directed against pancreatic β cells is the most essential pathogenic process in type 1 ...
Ivan Koprivica, Suzana Stanisavljević, Dragica Mićanović, Ivana Stojanović, Đorđe Miljković   +4 more
wiley   +1 more source

Optoregulated mRNA Delivery Controls Pleiotropic Immune Signaling for Tumor‐Targeted Therapy

Angewandte Chemie, EarlyView.
A light‐induced transfection system (LITS) was designed to precisely control the delivery of mRNA, achieving spatiotemporal de‐coupling of the pleotropic inflammatory and tolerogenic signals of interleukin‐2 to conduct safe eradication of tumors. Abstract Spatiotemporal control of protein expression remains a critical challenge in messenger RNA (mRNA ...
Pengwen Chen, Guanghao Hu, Yuki Nakashima, Zhining Xu, Takayoshi Watanabe, Soichiro Kondo, Ervin Kovács, Horacio Cabral   +7 more
wiley   +2 more sources

Comprehensive proteomic and pathological profiling identifies PRAS40 as a novel biomarker and mediator of primary immune checkpoint blockade resistance in non-small cell lung cancer. [PDF]

Cancer Immunol Immunother
Mao N, He C, Kuang J, Wang C, Yang Z.
europepmc   +1 more source

Cutting Edge: Induction of Enhanced CTL-Dependent Protective Immunity In Vivo by N-End Rule Targeting of a Model Tumor Antigen [PDF]

, 1999
Timothy W. Tobery, Robert F. Siliciano
openalex   +1 more source

Establishment and molecular profiling of a PDX model of a metachronous brain tumor in a patient with constitutional mismatch repair deficiency with biallelic MSH6 variant

Animal Models and Experimental Medicine, EarlyView.
A 6½‐year‐old girl was diagnosed with a medulloblastoma, SHH activated, subtype 3 and TP53 mutant (somatic). After surgery and chemotherapy, she was monitored with quarterly magnetic resonance imaging (MRI) scans and remained free of disease for almost 4 years.
Daniel Antunes Moreno, Bruna Minniti Mançano, Mirella Baroni, Eric Allison Philot, Felipe Antonio de Oliveira Garcia, Murilo Bonatelli, Flávia Escremim de Paula, Iara Viana Vidigal Santana, Gustavo Ramos Teixeira, Mauricio Yamanari, Luciane Sussuchi da Silva, André Escremim de Paula, Augusto Perazzolo Antoniazzi, Adrian Willig, Xiaobin Xing, Zhenyu Xu, Lucas Lourenço, Carlos Almeida Junior, Silvia Aparecida Teixeira, Rui Manuel Reis   +19 more
wiley   +1 more source