Results 31 to 40 of about 180,278 (321)

Harnessing Radiation Biology to Augment Immunotherapy for Glioblastoma

open access: yesFrontiers in Oncology, 2019
Glioblastoma is the most common adult primary brain tumor and carries a dismal prognosis. Radiation is a standard first-line therapy, typically deployed following maximal safe surgical debulking, when possible, in combination with cytotoxic chemotherapy.
Karishma R. Rajani   +5 more
doaj   +1 more source

Cautious addition of targeted therapy to PD-1 inhibitors after initial progression of BRAF mutant metastatic melanoma on checkpoint inhibitor therapy

open access: yesBMC Cancer, 2021
Background Virtually all metastatic patients with metastatic melanoma who progress after initial treatment with PD-1 or CTLA-4 directed antibodies will die of their disease. Salvage options are urgently needed.
Wolfram Samlowski, Camille Adajar
doaj   +1 more source

Microorganismos tolerantes a metales pesados del pasivo minero Santa Rosa, Jangas (Perú)

open access: yesRevista Peruana de Biología, 2019
En el presente trabajo estudiamos el grado de tolerancia a metales pesados de hongos y bacterias aisladas de suelos con y sin rizósfera, con el propósito de conocer su potencial para aplicaciones en biorremediación.
Loyer Muñoz-Silva   +3 more
doaj   +1 more source

Overexpressed pseudogene MT1L associated with tumor immune infiltrates and indicates a worse prognosis in BLCA

open access: yesWorld Journal of Surgical Oncology, 2021
Background BLCA is a common cancer worldwide, and it is both aggressive and fatal. Immunotherapy (ICT) has achieved an excellent curative effect in BLCA; however, only some BLCA patients can benefit from ICT.
Yanpeng Ding   +9 more
doaj   +1 more source

Presence of Adult Companion Goats Favors the Rumen Microbial and Functional Development in Artificially Reared Kids

open access: yesFrontiers in Veterinary Science, 2021
Newborn dairy ruminants are usually separated from their dams after birth and fed on milk replacer. This lack of contact with adult animals may hinder the rumen microbiological and physiological development.
Juan Manuel Palma-Hidalgo   +5 more
doaj   +1 more source

CTL++: Evaluating Generalization on Never-Seen Compositional Patterns of Known Functions, and Compatibility of Neural Representations [PDF]

open access: yesarXiv, 2022
Well-designed diagnostic tasks have played a key role in studying the failure of neural nets (NNs) to generalize systematically. Famous examples include SCAN and Compositional Table Lookup (CTL). Here we introduce CTL++, a new diagnostic dataset based on compositions of unary symbolic functions.
arxiv  

Integrated Characterization of lncRNA-Immune Interactions in Prostate Cancer

open access: yesFrontiers in Cell and Developmental Biology, 2021
Prostate cancer is among the top mortality factors in male around the world. Long non-coding RNAs (lncRNAs) have been shown to play crucial roles in tumor biology and immunology.
Wei Hu   +4 more
doaj   +1 more source

Upaya Meningkatkan Motivasi dan Pemahaman Siswa pada Materi Geometri dan Pengukuran Melalui Kegiatan “Remase” di SMP 33 Semarang

open access: yesKreano: Jurnal Matematika Kreatif-Inovatif, 2013
Masalah utama yang dikaji dalam pengembangan inovasi ini adalah upaya untuk meningkatkan motivasi dan hasil belajar matematika siswa khususnya pada materi Geometri dan pengukuran.
Zaenal Abidin, Tri Mulyono Edi Saputro
doaj   +1 more source

CTL-Derived Exosomes Enhance the Activation of CTLs Stimulated by Low-Affinity Peptides [PDF]

open access: yesFrontiers in Immunology, 2019
Abstract Cytotoxic T cells (CTLs) of low TCR affinity play an important role in the control of intracellular pathogens and cancers; however, the mechanisms by which lower-affinity CTLs are activated and maintained are not well understood.
Zhengguo Xiao   +3 more
openaire   +4 more sources

CTLs: Killers of intracellular bacteria

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Many microbial pathogens have evolved a range of capabilities to evade host immune defense mechanisms and to survive and multiply in host cells. The presence of host intracellular bacteria makes it difficult for specific antibodies to function. After the intracellular bacteria escape the attack of the innate immune system, such as phagocytes, they ...
Li Tian   +8 more
openaire   +3 more sources

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