A single amino acid substitution in the alpha 3 domain of an H-2 class I molecule abrogates reactivity with CTL. [PDF]
, 1987 We previously described a somatic cell expressing a variant H-2Dd molecule that did not serve as a target for alloreactive anti-Dd CTL. The mutant cell line had been isolated by its failure to express a serological epitope present on the H-2Dd alpha 3 ...
Bluestone, JA, Potter, TA, Rajan, TV
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Advances in Targeted Drug Delivery in Melanoma
Asian Pacific Journal of Cancer Biology, 2021 Cancer remains a major killer of mankind. Failure of conventional chemotherapy has resulted in recurrence and development of virulent multi drug resitant (MDR) phenotypes adding to the complexity and diversity of this deadly disease. Melanoma is the most
Pemula Gowtham
doaj +1 more source
Social representation of competition and fraud [PDF]
, 2013 Good citizenship includes fair competitive strategies. Dishonest competitive behaviour – such as fraud – can reflect the absence of one main characteristic of good citizenship as mindfulness of laws and social rules.
Orosz, Gábor, Roland-Lévy, Christine
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The cooperative competitive citizen [PDF]
, 2013 Each human group and each society is a complex system of cooperative and competitive relationships. These two relations are intertwined, however, it is not indifferent in what way and to what extent.
Fülöp, Márta, Takács, Szabolcs
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CTLs: Killers of intracellular bacteria
Frontiers in Cellular and Infection Microbiology, 2022 Many microbial pathogens have evolved a range of capabilities to evade host immune defense mechanisms and to survive and multiply in host cells. The presence of host intracellular bacteria makes it difficult for specific antibodies to function. After the intracellular bacteria escape the attack of the innate immune system, such as phagocytes, they ...
Li Tian +8 more
openaire +3 more sources
Swimming Exercise Training Attenuates the Lung Inflammatory Response and Injury Induced by Exposing to Waterpipe Tobacco Smoke [PDF]
Addiction and Health, 2020 Background: The use of waterpipe tobacco smoking (WTS) is on the rise throughout the world, especiallyamong young people and even athletes. There is a belief among consumers that exercise prevents the harmfuleffects of hookah smoke on the body.
Mohammad Reza Nakhaee +6 more
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CTL-Derived Exosomes Enhance the Activation of CTLs Stimulated by Low-Affinity Peptides [PDF]
Frontiers in Immunology, 2019 Abstract Cytotoxic T cells (CTLs) of low TCR affinity play an important role in the control of intracellular pathogens and cancers; however, the mechanisms by which lower-affinity CTLs are activated and maintained are not well understood.
Zhengguo Xiao +3 more
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Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity
Journal of Experimental Medicine, 1996 Cytotoxic T lymphocytes (CTLs) are a critical component of the immune response to tumors. Tumor-derived peptide antigens targeted by CTLs are being defined for several human tumors and are potential immunogens for the induction of specific antitumor ...
C. Celluzzi +4 more
semanticscholar +1 more source
Synthetic phospholipid vesicles containing a purified viral antigen and cell membrane proteins stimulate the development of cytotoxic T lymphocytes [PDF]
, 1979 Synthetic phospholipid vesicles (liposomes) containing the purified glycoprotein (G) of vesicular stomatitis virus (VSV) and solubilized membrane proteins from cells of the appropriate H-2 haplotype elicited H-2-restricted cytotoxic T lymphocytes (CTL ...
Baltimore, David +4 more
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Recent research and clinical progress of CTLA-4-based immunotherapy for breast cancer
Frontiers in Oncology, 2023 Breast cancer is characterized by a high incidence rate and its treatment challenges, particularly in certain subtypes. Consequently, there is an urgent need for the development of novel therapeutic approaches.
Hongsheng Zhang +6 more
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