Results 51 to 60 of about 180,278 (321)
Journal of International Medical Research, 2020 Objective Although N 6 -methyladenosine (m 6 A) RNA methylation is the most common mRNA modification process, few studies have examined the role of m 6 A in stomach adenocarcinomas (STADs).
Pingfan Mo +6 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Neuroblastoma is one of the malignant solid tumors with the highest mortality in childhood. Targeted immunotherapy still cannot achieve satisfactory results due to heterogeneity and tolerance.
Wenjuan Kang +3 more
doaj +1 more source
Rich Counter-Examples for Temporal-Epistemic Logic Model Checking [PDF]
EPTCS 78, 2012, pp. 39-53, 2012 Model checking verifies that a model of a system satisfies a given property, and otherwise produces a counter-example explaining the violation. The verified properties are formally expressed in temporal logics. Some temporal logics, such as CTL, are branching: they allow to express facts about the whole computation tree of the model, rather than on ...
arxiv +1 more source
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases
FEBS Letters, EarlyView.The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher +6 more
wiley +1 more source
Toward Low-Power Flash Memory: Prospect of Adopting Crystalline Oxide as Charge Trapping Layer
IEEE Journal of the Electron Devices Society, 2016 The rapid growth of data center, ubiquitous cloud computing, and mobile gadgets has made flash memory one of the major semiconductor markets. The booming request of flash memory has not only brought substantial economic and societal benefit but led to ...
Kuen-Yi Chen +3 more
doaj +1 more source
Influencers’ Engagement in a Brand Communication: Latvia and Cyprus Cases
Economics and Culture, 2020 Research purpose. Social networks have become an integral part of life, making social media one of the most significant advertising platforms, which, according to many experts and scientists, is one of the most effective brand communication techniques ...
Antoniades George +4 more
doaj +1 more source
Molecular Cancer, 2021 Background AMP-activated protein kinase (AMPK) is a metabolic sensor that maintains energy homeostasis. AMPK functions as a tumor suppressor in different cancers; however, its role in regulating antitumor immunity, particularly the function of regulatory
Ram Hari Pokhrel +9 more
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Cell, 1995 The potent and specific lytic activity of CTLs can occur by at least two distinct pathways. In the secretion and perforin-mediated pathway, the direct effect(s) on the target cell membrane of the pore-forming agent perforin, probably in conjunction with granzymes, also secreted from the CTLs, causes the target's demise.
openaire +3 more sources
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source