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The Satisfiability Problem for Probabilistic CTL [PDF]
2008 23rd Annual IEEE Symposium on Logic in Computer Science, 2008 We study the satisfiability problem for qualitative PCTL (probabilistic computation tree logic), which is obtained from "ordinary" CTL by replacing the EX, AX, EU, and AU operators with their qualitative counterparts X > 0, X = 1, U > 0, and U = 1, respectively.
Brázdil, T +3 more
openaire +3 more sources
HeliyonDespite advancements in road safety, Powered Two-Wheelers (PTWs) remain a vulnerable group with disproportionately high crash rates. This paper presents an in-depth analysis of PTW crashes in six European countries, with a case study of Loss of Control ...
Stephen Kome Fondzenyuy +5 more
doaj +1 more source
iScience, 2023 Summary: TRIM24 is an oncogenic chromatin reader that is frequently overexpressed in human tumors and associated with poor prognosis. However, TRIM24 is rarely mutated, duplicated, or rearranged in cancer.
Lalit R. Patel +8 more
doaj +1 more source
CTL mobilization to virus-infected tissue requires CD4+ T cell help
Nature, 2009 CD4+ T helper cells are well known for their role in providing critical signals during priming of cytotoxic CD8+ T lymphocyte (CTL) responses in vivo. T-cell help is required for the generation of primary CTL responses as well as in promoting protective ...
Y. Nakanishi +3 more
semanticscholar +1 more source
Progress of immune checkpoint inhibitors for the treatment of myelodysplastic syndrome [PDF]
Jichu yixue yu linchuang, 2021 Immune checkpoint inhibitor(ICI) is a potential treatment for MDS by inhibiting the escape of tumor cells and enhancing immune responses. This article reviewed the efficacy and adverse events of clinical trials focusing on PD-1/PD-L1 and CTLA-4 ...
ZHANG Ruo-xi, HAN Bing
doaj
Recognition of viral glycoproteins by influenza A-specific cross- reactive cytolytic T lymphocytes [PDF]
, 1980 Two populations of cytolytic T lymphocytes (CTL) generated after influenza A virus infection can be distinguished into one with specificity for the sensitizing hemagglutinin type and a second with cross-reactivity for antigens induced by other type-A ...
Allen, H. +4 more
core +2 more sources
Scientific ReportsThe epigenetic regulation of N6-methyladenosine (m6A) has attracted considerable interest in tumor research, but the potential roles of m6A regulator-related genes, remain largely unknown within the context of gastric cancer (GC) and tumor ...
Bin Peng +8 more
doaj +1 more source
Pharmacological Research, 2023 Circulating tumour-derived extracellular vesicles are supposed to contribute to the spreading of distant metastasis. In this study, we investigated the impact of circulating extracellular vesicles derived from tumour-endothelial cells (TEVs) in the ...
Malvina Koni +9 more
doaj +1 more source
PLoS ONE, 2012 Cytotoxic T lymphocyte (CTL) responses targeting specific HIV proteins, in particular Gag, have been associated with relative control of viral replication in vivo. However, Gag-specific CTL can also be detected in individuals who do not control the virus
B. Mothe +22 more
semanticscholar +1 more source
Conditional Superagonist CTL Ligands for the Promotion of Tumor-Specific CTL Responses [PDF]
The Journal of Immunology, 2010 Abstract Although it has been demonstrated that CTLs can be raised against tumor-associated self-antigens, achieving consistent and effective clinical responses has proven challenging. Superagonist altered peptide ligands (APLs) can often elicit potent antitumor CTL responses where the native tumor-associated epitope fails.
C. Siddiq Abdul-Alim +2 more
openaire +3 more sources