Results 61 to 70 of about 180,278 (321)

Molecular Characterization and Clinical Relevance of ALDH2 in Human Cancers

Frontiers in Medicine, 2022
Background: Aldehyde dehydrogenase 2 (ALDH2) is well-known to be a key enzyme in alcohol metabolism. However, a comprehensive understanding of ALDH2 across human cancers is lacking.Methods: A systematic and comprehensive analysis of the molecular ...
Bo Ma, Zaoqu Liu, Zaoqu Liu, Zaoqu Liu, Hui Xu, Hui Xu, Hui Xu, Long Liu, Tao Huang, Lingfang Meng, Libo Wang, Yuyuan Zhang, Lifeng Li, Xinwei Han, Xinwei Han, Xinwei Han   +15 more
doaj   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Computation Tree Logic with Deadlock Detection [PDF]

Logical Methods in Computer Science, Volume 5, Issue 4 (December 22, 2009) lmcs:758, 2009
We study the equivalence relation on states of labelled transition systems of satisfying the same formulas in Computation Tree Logic without the next state modality (CTL-X). This relation is obtained by De Nicola & Vaandrager by translating labelled transition systems to Kripke structures, while lifting the totality restriction on the latter.
arxiv   +1 more source

Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients

Molecular Oncology, EarlyView.
Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha, Steven Kao, Veronica K. Cheung, Wendy A. Cooper, Nico van Zandwijk, John E. J. Rasko, Dannel Yeo   +6 more
wiley   +1 more source

Engineering a novel subunit vaccine against SARS-CoV-2 by exploring immunoinformatics approach

Informatics in Medicine Unlocked, 2020
As the number of infections and deaths caused by the recent COVID-19 pandemic is increasing dramatically day-by-day, scientists are rushing towards developing possible countermeasures to fight the deadly virus, SARS-CoV-2.
Bishajit Sarkar, Md Asad Ullah, Yusha Araf, Mohammad Shahedur Rahman   +3 more
doaj  

Permanent diabetes insipidus in a patient with mesothelioma treated with immunotherapy

Archives of Endocrinology and Metabolism, 2020
SUMMARY Checkpoint inhibitors have substantially improved the prognosis for patients with advanced malignancy. Treatment with immunomodulants has the ability to reactivate the immune system against tumor cells, but can also trigger the development of ...
Lucia Brilli, Luana Calabrò, Michele Campanile, Tania Pilli, Cristina Agostinis, Alfonso Cerase, Michele Maio, Maria Grazia Castagna   +7 more
doaj   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

Peningkatan Kemampuan Menulis Teks Eksplanasi dengan Metode Contextual Teaching and Learning pada Siswa Kelas V

Jurnal Educatio FKIP UNMA, 2021
Penelitian ini bertujuan meningkatkan kualitas proses dan hasil pembelajaran kemampuan menulis teks eksplanasi dengan metode CTL pada siswa kelas V SDN 2 Galuk Kedungtuban Blora Tahun Pelajaran 2020/2021.
Nova Korniawanto
doaj   +1 more source

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

Molecular Oncology, EarlyView.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar, Shima Shahbaz, Anthea C. Peters, Spencer B. Gibson, Shokrollah Elahi   +4 more
wiley   +1 more source

Peningkatan Kemampuan Menganalisis Informasi dari Iklan Melalui Metode Contextual Teaching and Learning pada Siswa Sekolah Dasar

Jurnal Educatio FKIP UNMA, 2021
Penelitian ini bertujuan untuk meningkatkan kemampuan menganalisis informasi dari iklan melalui metode CTL pada siswa kelas V SDN Undaan Tengah Kudus Tahun Pelajaran 2020/2021. Penelitian tindakan kelas ini merupakan penelitian melalui 2 siklus.
Dwi Hadi Abdul Aziz
doaj   +1 more source