Results 81 to 90 of about 3,017 (208)

Post‐Transplant Bendamustine as a Platform for Immune Modulation After Allogeneic Hematopoietic Cell Transplantation

European Journal of Haematology, Volume 117, Issue 4, Page 739-749, October 2026.
ABSTRACT Post‐transplant cyclophosphamide (PT‐CY) remains the standard of care for graft‐versus‐host disease (GvHD) prophylaxis in haploidentical hematopoietic cell transplantation (HCT), yet relapse, delayed immune reconstitution, infections, and organ toxicity represent persistent and clinically meaningful limitations.
Megan J. Cracchiolo, Richard J. Simpson, Emmanuel Katsanis   +2 more
wiley   +1 more source

The Promoter of a Lysosomal Membrane Transporter Gene, CTNS, Binds Sp-1, Shares Sequences with the Promoter of an Adjacent Gene, CARKL, and Causes Cystinosis If Mutated in a Critical Region [PDF]

, 2001
Although >55 CTNS mutations occur in patients with the lysosomal storage disorder cystinosis, no regulatory mutations have been reported, because the promoter has not been defined. Using CAT reporter constructs of sequences 5′ to the CTNS coding sequence,
Braun, Paula, Huizing, Marjan, Chou, Janice Y., Brodie, Chaya, Anikster, Yair, Phornphutkul, Chanika, Gahl, William A.   +6 more
core   +1 more source

Genetic organisation, mobility and predicted functions of genes on integrated, mobile genetic elements in sequenced strains of Clostridium difficile.

PLoS ONE, 2011
BackgroundClostridium difficile is the leading cause of hospital-associated diarrhoea in the US and Europe. Recently the incidence of C. difficile-associated disease has risen dramatically and concomitantly with the emergence of 'hypervirulent' strains ...
Michael S M Brouwer, Philip J Warburton, Adam P Roberts, Peter Mullany, Elaine Allan   +4 more
doaj   +1 more source

Clinical Predictors of Response in Chronic Graft‐Versus‐Host Disease: Results From the “Predicting the Quality of Response to Specific Treatments (PQRST)” Trial

American Journal of Hematology, Volume 101, Issue 9, Page 2280-2287, September 2026.
ABSTRACT Despite significant progress in chronic GVHD therapies, challenges remain in understanding pleomorphic phenotypes and varying responses to treatment. The aim of this study was to identify predictors of treatment response. We conducted a prospective, observational cohort study of patients beginning first‐, second‐, or third‐line systemic ...
Betty K. Hamilton, Lynn Onstad, Paul A. Carpenter, Joseph Pidala, George Chen, Corey Cutler, Najla El Jurdi, Nosha Farhadfar, Mark Juckett, Carrie L. Kitko, Catherine J. Lee, Stephanie J. Lee   +11 more
wiley   +1 more source

Evaluation of topical cysteamine therapy in the CTNS−/− knockout mouse using in vivo confocal microscopy [PDF]

, 2011
PurposeThe purpose of this study was to assess the ability of quantitative in vivo confocal microscopy (CM) to detect changes in cystine crystal volume in the cystinosisn (Ctns−/−)mouse cornea following topical cysteamine therapy.MethodsFifteen Ctns ...
Nien, Chyong Jy, Flynn, Kevin J., Simpson, Jennifer L., Jester, James V.   +3 more
core   +1 more source

Anatomical Variation of Absent Facial Vein: Implications for Facial Reanimation Surgery

Head &Neck, Volume 48, Issue 9, Page 2499-2504, September 2026.
ABSTRACT Background The facial vein is the standard recipient vessel in facial reanimation surgery. Its complete absence is rarely described but may cause major challenges during free functional muscle transfer (FFMT). This study aimed to determine the prevalence and predictors of facial vein absence and assess its surgical relevance in facial ...
Cam T. Nguyen, Mark Fricke, Justus Osterloh, Ayla A. Hohenstein, Steffen U. Eisenhardt   +4 more
wiley   +1 more source

Problems in comparing tobacco regulatory models and excise when only two countries are considered

Addiction, EarlyView.
Simon Chapman, Sam Egger, Becky Freeman
wiley   +1 more source

Beyond Traditional Screening: The Future of Heart Failure Detection With Biomarkers and AI

iNew Medicine, Volume 2, Issue 3, September 2026.
Advancing HF Screening: Integrating Technology and Risk Factors Across Eras. This diagram provides a comprehensive review of the historical developments and projected trends of heart failure (HF) screening methodologies, with the prevalent risk factors for HF depicted at the base.
Xiaofeng Fang, Yinbo Xu, Yiting Zhao, Liuyi Li, Zhengyi Cheng, Zhongqi Zhang, Yuhang Luo, Qiaoling Liu, Chen Gong, Shichun Shen   +9 more
wiley   +1 more source

Temporary VAT Reduction in Vietnam: Consumer Behavior Analysis

International Studies of Economics, Volume 21, Issue 3, Page 249-263, September 2026.
ABSTRACT This study investigates the impact of temporary VAT rate changes on consumer behavior in Vietnam, particularly concerning the VAT reduction implemented during 2023–2024. The research analyzes annual survey data and household expenditure reports to assess changes in consumer spending on durable goods during the first half of 2024 (2024 H1 ...
Hang Thi Thu Trinh
wiley   +1 more source

Neurocardiology: Brain–Heart Interactions in the Heart

MedComm, Volume 7, Issue 9, September 2026.
The heart and brain maintain systemic homeostasis through bidirectional communication involving neural, biochemical, and mechanical pathways. Dysregulation of these pathways contributes to a spectrum of conditions involving heart–brain interactions, including Takotsubo syndrome, the epileptic heart, stroke–heart syndrome, heart failure, cardiac ...
Wentao Wang, Hao Jia, Han Han, Jiangping Song   +3 more
wiley   +1 more source