Sexual Dimorphism in Brown Adipose Tissue Activation and White Adipose Tissue Browning [PDF]
International Journal of Molecular Sciences, 2022 The present narrative review gathers the studies reported so far, addressing sex differences in the effects of cold exposure, feeding pattern and age on brown adipose tissue (BAT) thermogenesis and white adipose tissue (WAT) browning. In rodents, when exposed to decreasing temperatures, females activate thermogenesis earlier. Results obtained in humans
Iker Gomez-Garcia +2 more
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Lipid Profiling Reveals Browning Heterogeneity of White Adipose Tissue by Β3-Adrenergic Stimulation
Biomolecules, 2019 Background: White adipose tissue (WAT) browning confers beneficial effects on metabolic diseases. However, visceral adipose tissue (VAT) is not as susceptible to browning as subcutaneous adipose tissue (SAT).
Ping He +14 more
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White adipose tissue browning and peroxisome proliferator activated receptors in MASLD [PDF]
Frontiers in EndocrinologyMetabolic dysfunction associated steatotic liver disease (MASLD) has emerged as the predominant global etiology of chronic liver disease, with its incidence and prevalence continuously rising amid the obesity epidemic. The human body contains two primary
Zexuan Li, Huikuan Chu, Ling Yang
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Lytic cocktail: An effective method to alleviate severe burn induced hyper-metabolism through regulating white adipose tissue browning [PDF]
Heliyon, 2022 Background: Browning of white adipose tissue is associated with elevated resting metabolic rates and is considered to be one of the indispensable causes of hypermetabolism in burn patients.
Meng Zhang +8 more
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Nucleophosmin3 carried by small extracellular vesicles contribute to white adipose tissue browning [PDF]
Journal of Nanobiotechnology, 2022 Background Browning of white adipose tissue (WAT) is a particularly appealing target for therapeutics in the treatment of obesity and related metabolic diseases.
Yan Zhang +4 more
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The Long Noncoding RNA ΒFaar Promotes White Adipose Tissue Browning and Prevents Diet‐Induced Obesity [PDF]
Advanced ScienceThe conversion of white adipose tissue (WAT) to brown adipose tissue (BAT) is a promising strategy for obesity treatment. It is previously identified βFaar as a conserved long noncoding RNA (lncRNA) regulator of islet β‐cell function in individuals with ...
Yue Yang +13 more
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LLTH induces white adipose tissue browning via NF κB inhibition in ATM [PDF]
Scientific ReportsThis study aimed to explore the role of macrophage polarization and TLR4/NF-κB pathway in promoting browning of white adipose tissue through different hypoxic exercises.
Yingli Lu +4 more
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GRP75 triggers white adipose tissue browning to promote cancer-associated cachexia [PDF]
Signal Transduction and Targeted TherapyCachexia, which affects 50–80% of cancer patients, is a debilitating syndrome that leads to 20% of cancer-related deaths. A key feature of cachexia is adipose tissue atrophy, but how it contributes to the development of cachexia is poorly understood ...
Xu Chen +14 more
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Nutrition & Metabolism, 2022 Adipose tissues are dynamic tissues that play crucial physiological roles in maintaining health and homeostasis. Although white adipose tissue and brown adipose tissue are currently considered key endocrine organs, they differ functionally and ...
Sabrina Azevedo Machado +6 more
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Renaissance of Brown Adipose Tissue [PDF]
Hormone Research in Paediatrics, 2011 The recent discovery of functional brown adipose tissue in human adults raised this tissue again into the focus of current investigations concerning human energy homeostasis. Brown fat is a key thermogenic tissue and is essential for non-shivering thermogenesis in the human newborn and hibernating mammals.
Tews, D., Wabitsch, M.
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