Results 21 to 30 of about 14,567 (295)

Natural Extracts That Stimulate Adipocyte Browning and Their Underlying Mechanisms

open access: yesAntioxidants, 2021
Despite progress in understanding the developmental lineage and transcriptional factors regulating brown and beige adipocytes, the role of environmental modifiers, such as food components and natural extracts, remains to be elucidated.
Min-Kyeong Lee   +2 more
doaj   +1 more source

Transcriptional fingerprinting of "browning" white fat identifies NRG4 as a novel adipokine [PDF]

open access: yes, 2014
Brown adipocytes help to maintain body temperature by the expression of a unique set of genes that facilitate cellular metabolic events including uncoupling protein 1-dependent thermogenesis.
Christian, Mark, Christian, M
core   +1 more source

circNrxn2 Promoted WAT Browning via Sponging miR-103 to Relieve Its Inhibition of FGF10 in HFD Mice

open access: yesMolecular Therapy: Nucleic Acids, 2019
The accumulation of excess white adipose tissue (WAT) has harmful consequences on metabolic health. WAT browning confers beneficial effects on adiposity, insulin resistance, and hyperlipidemia.
Tiantian Zhang   +4 more
doaj   +1 more source

Reprogramming of hepatic fat accumulation and 'browning' of adipose tissue by the short-chain fatty acid acetate [PDF]

open access: yes, 2016
Background/Objectives: Short-chain fatty acids, produced by microbiome fermentation of carbohydrates, have been linked to a reduction in appetite, body weight and adiposity.
Sahuri Arisoylu, M.   +8 more
core   +1 more source

Brown Adipose Tissue in a Newborn [PDF]

open access: yesBaylor University Medical Center Proceedings, 2008
A premature infant boy of 35 weeks and 4 days weighing 2605 g was found to have bilateral supraclavicular masses at 13 days of life. He had persistent pulmonary hypertension of the newborn and thrombocytopenia. Delivery was by cesarean section for nonreassuring fetal status, and Apgar scores were 5 at 1 minute and 8 at 5 minutes. Initial radiographs
Brett W, Carter, William G, Schucany
openaire   +2 more sources

NRF2 is essential for adaptative browning of white adipocytes

open access: yesRedox Biology, 2023
White adipose tissue browning, defined by accelerated mitochondrial metabolism and biogenesis, is considered a promising mean to treat or prevent obesity-associated metabolic disturbances.
Marco Bauzá-Thorbrügge   +7 more
doaj   +1 more source

Functional Inactivation of Mast Cells Enhances Subcutaneous Adipose Tissue Browning in Mice

open access: yesCell Reports, 2019
Summary: Adipose tissue browning and systemic energy expenditure provide a defense mechanism against obesity and associated metabolic diseases. In high-cholesterol Western diet-fed mice, mast cell (MC) inactivation ameliorates obesity and insulin ...
Xian Zhang   +10 more
doaj   +1 more source

E0771 and 4T1 murine breast cancer cells and interleukin 6 alter gene expression patterns but do not induce browning in cultured white adipocytes

open access: yesBiochemistry and Biophysics Reports, 2019
Breast cancer remains a substantial clinical problem worldwide, and cancer-associated cachexia is a condition associated with poor prognosis in this and other malignancies.
Janina V. Pearce   +6 more
doaj   +1 more source

Targeting the Epicardial Adipose Tissue

open access: yes, 2020
Epicardial fat (EAT) is the visceral fat depot of the heart. Given its rapid metabolism, organ fat specificity, and simple objective measurability, epicardial fat can serve as a target for pharmaceutical agents targeting the adipose tissue. EAT has shown
Iacobellis, Gianluca
core   +1 more source

Brown adipose tissue and thermogenesis [PDF]

open access: yesHormone Molecular Biology and Clinical Investigation, 2014
Abstract The growing understanding of adipose tissue as an important endocrine organ with multiple metabolic functions has directed the attention to the (patho)physiology of distinct fat depots. Brown adipose tissue (BAT), in contrast to bona fide white fat, can dissipate ...
Anna, Fenzl, Florian W, Kiefer
openaire   +2 more sources

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