Results 41 to 50 of about 1,840,318 (295)

Towards clinical translation of upscaled osteogenic grafts using human adipose tissue progenitors [PDF]

, 2012
Tissue engineering is an emerging strategy in medical field that focuses on regeneration or replacement of lost or damaged tissue and organs. Most of the tissues in human body have no or limited self renewal and regeneration potential which decrease with
Güven, Sinan
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Pharmacological Activation of Thyroid Hormone Receptors Elicits a Functional Conversion of White to Brown Fat

Cell Reports, 2015
The functional conversion of white adipose tissue (WAT) into a tissue with brown adipose tissue (BAT)-like activity, often referred to as “browning,” represents an intriguing strategy for combating obesity and metabolic disease.
Jean Z. Lin, Alexandro J. Martagón, Stephanie L. Cimini, Daniel D. Gonzalez, David W. Tinkey, Amadeo Biter, John D. Baxter, Paul Webb, Jan-Åke Gustafsson, Sean M. Hartig, Kevin J. Phillips   +10 more
doaj   +1 more source

White-to-brown adipose switching promotes bladder cancer progression

Neoplasia: An International Journal for Oncology Research
The invasion of bladder cancer into perivesical adipose tissue represents a watershed event in tumor progression, accompanied by a dramatic deterioration in clinical outcomes.
Mingchao Gao, Chunni Li, Wenjie Li, Junyi Xie, Juntian Long, Mingli Luo, Jintao Hu, Cong Lai, Tianhang Lan, Dongxi Zhu, Wenlong Zhong, Wang He   +11 more
doaj   +1 more source

An update on brown adipose tissue and obesity intervention: Function, regulation and therapeutic implications

Frontiers in Endocrinology, 2023
Overweight and obesity have become a world-wide problem. However, effective intervention approaches are limited. Brown adipose tissue, which helps maintain body temperature and contributes to thermogenesis, is dependent on uncoupling protein1.
Xiaomeng Liu, Xiaomeng Liu, Zhi Zhang, Zhi Zhang, Yajie Song, Hengchang Xie, Meng Dong, Meng Dong   +7 more
doaj   +1 more source

A combined transcriptomics and lipidomics analysis of subcutaneous, epididymal and mesenteric adipose tissue reveals marked functional differences [PDF]

, 2010
Depot-dependent differences in adipose tissue physiology may reflect specialized functions and local interactions between adipocytes and surrounding tissues.
Kelder, T.A.J., Kooistra, Teake, MÜLLER M, Manieri, Monia, Evelo, C.T.A., Cinti, Saverio, Kelder, T., Saverio Cinti, Cinti, S., Müller, M.R., BOEKSCHOTEN M, Kelder, Thomas, MANIERI M, Manieri, M., Drevon, C.A., Evelo, C.T.A.; id_orcid, Christian A Drevon, Monia Manieri, Teake Kooistra, Chris Evelo, Boekschoten, M.V., Robert Kleemann, EVELO C, Müller, Michael, Caesar, R., KELDER T, Boekschoten, M., Christian A. Drevon, Thomas Kelder, Michael Müller, Robert Caesar, KOOISTRA T, Caesar, Robert, Kooistra, T., Kleemann, R., Robert Caesar, Michael Müller, Mark Boekschoten, Boekschoten, Mark, KLEEMANN R, Kleemann, Robert, Evelo, C., Evelo, Chris, Müller, M., DREVON CA, Drevon, Christian A., CAESAR R   +46 more
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ASK1 inhibits browning of white adipose tissue in obesity [PDF]

, 2020
Increasing energy expenditure via induction of adipose tissue browning has become an appealing strategy to treat obesity and associated metabolic complications.
Konrad, Daniel; https://orcid.org/, Item, Flurin, Borsigova, Marcela, Rudich, Assaf, Haim, Yulia, Wolfrum, Christian, Modica, Salvatore, Challa, Tenagne D, Lucchini, Fabrizio C, Wueest, Stephan; https://orcid.org/   +9 more
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A New Bioactive Glass‐Based Hybrid Bioink With Enhanced Cell Viability and Antibacterial Properties

Advanced Healthcare Materials, EarlyView.
Graphical illustration of the production and characterization process, demonstrating the multiple functions of the new hybrid gelatin methacryloyl‐silver‐bioactive glass (GAB) material. Created in https://BioRender.com. ABSTRACT Recent advances in three‐dimensional bioprinting (3DBP) technology enable the production of customized bone substitutes ...
Adam C. Marsh, Ehsanul Hoque Apu, Theofania Kleisoura, Romila Manchanda, Valerie Johnson, Ginger Ross, Ioannis Tsamesidis, Eleana Kontonasaki, DeMarcus Bunn, Ahmet Erdem, Neal D. Hammer, Kurt D. Hankenson, Christopher H. Contag, Nureddin Ashammakhi, Xanthippi Chatzistavrou   +14 more
wiley   +1 more source

Brown remodeling of white adipose tissue protects against abdominal aortic aneurysm via batokine FSTL1

EMBO Molecular Medicine
Abdominal aortic aneurysm (AAA) is a life-threatening vascular disease without effective medical therapies. Emerging evidence have suggested a crosstalk between adipose tissue and vascular cells. Besides, brown adipose tissue is considered beneficial for
Chunling Huang, Yuna Huang, Boshui Huang, Lei Yao, Zenghui Zhang, Luoxiao Dong, Chang Guan, Junping Li, Zhaoqi Huang, Sixu Chen, Yuan Jiang, Yuling Zhang, Jingfeng Wang, Yangxin Chen, Zhaoyu Liu   +14 more
doaj   +1 more source

Tbx15 is required for adipocyte browning induced by adrenergic signaling pathway

Molecular Metabolism, 2019
Objective: The T-box gene Tbx15 is abundantly expressed in adipose tissues, especially subcutaneous and brown fat. Although its expression is correlated with obesity, its precise biological role in adipose tissue is poorly understood in vivo.
Wei Sun, Xuemei Zhao, Zhengqi Wang, Yi Chu, Liufeng Mao, Shaoqiang Lin, Xuefei Gao, Yuna Song, Xiaoyan Hui, Shiqi Jia, Shibing Tang, Yong Xu, Aimin Xu, Kerry Loomes, Cunchuan Wang, Donghai Wu, Tao Nie   +16 more
doaj   +1 more source

The anti-angiogenic herbal composition Ob-X inhibits adipose tissue growth in obese mice [PDF]

, 2009
Objective: The growth and development of adipose tissue are thought to be associated with angiogenesis and extracellular matrix remodeling. Since the composition of the herbal extract called Ob-X has been shown to have both anti-angiogenic and matrix ...
Min-Young Kim, Byung-Young Park, Eun kyu Park, Hyunghee Lee, Yeonhee Hong, Seolwha Choi, Hee Suk Lee, Jong Cheon Hahm, Michung Yoon, Jinmi Lee   +9 more
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