Results 101 to 110 of about 3,058 (215)

Clinical Predictors of Response in Chronic Graft‐Versus‐Host Disease: Results From the “Predicting the Quality of Response to Specific Treatments (PQRST)” Trial

open access: yesAmerican Journal of Hematology, Volume 101, Issue 9, Page 2280-2287, September 2026.
ABSTRACT Despite significant progress in chronic GVHD therapies, challenges remain in understanding pleomorphic phenotypes and varying responses to treatment. The aim of this study was to identify predictors of treatment response. We conducted a prospective, observational cohort study of patients beginning first‐, second‐, or third‐line systemic ...
Betty K. Hamilton   +11 more
wiley   +1 more source

Disruption of a cystine transporter downregulates expression of genes involved in sulfur regulation and cellular respiration

open access: yesBiology Open, 2016
Cystine and cysteine are important molecules for pathways such as redox signaling and regulation, and thus identifying cellular deficits upon deletion of the Saccharomyces cerevisiae cystine transporter Ers1p allows for a further understanding of cystine
Jessica A. Simpkins   +10 more
doaj   +1 more source

The HEAT Repeat Protein MROH1 Deficiency Leads to Reduced Circulating Thyroid Hormone Levels in Mice

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
Global Mroh1 deficiency in male mice is associated with reduced circulating thyroid hormone level, late‐onset thyroid follicular remodelling, and lower whole‐thyroid abundance of Nkx2‐1, Foxe1, and Tg transcripts. These findings support a role for MROH1 in maintaining thyroid homeostasis and structural integrity.
Nami Ohuchi   +12 more
wiley   +1 more source

Anatomical Variation of Absent Facial Vein: Implications for Facial Reanimation Surgery

open access: yesHead &Neck, Volume 48, Issue 9, Page 2499-2504, September 2026.
ABSTRACT Background The facial vein is the standard recipient vessel in facial reanimation surgery. Its complete absence is rarely described but may cause major challenges during free functional muscle transfer (FFMT). This study aimed to determine the prevalence and predictors of facial vein absence and assess its surgical relevance in facial ...
Cam T. Nguyen   +4 more
wiley   +1 more source

Effect of ELX-02 on exogenous CTNS protein expressed from pCMV-driven constructs.

open access: yes, 2019
HEK293 cells transfected with expression plasmids containing a pCMV-driven CTNS-DsRed or CTNSW138X-DsRed fusion construct. A. (Top) Confocal images show CTNS-DsRed and W138X-DsRed fluorescence without ELX-02 treatment (400 X, scale bar = 100 μm); (middle)
Pedro Huertas (4891903)   +9 more
core   +1 more source

Quantitative in vivo and ex vivo confocal microscopy analysis of corneal cystine crystals in the Ctns−/− knockout mouse [PDF]

open access: yes, 2011
PurposeThe purpose of this study was to assess the ability of quantitative in vivo confocal microscopy to characterize the natural history and detect changes in crystal volume in corneas from a novel animal model of cystinosis, the cystinosin (Ctns ...
Nien, Chyong Jy   +5 more
core   +1 more source

Hypertension, but Not Cancer or Obesity, Is Compatible With Extreme Longevity: A Multi‐Institution Analysis of 733,919 US Centenarians

open access: yes
Journal of the American Geriatrics Society, EarlyView.
Fateme Nateghi Haredasht   +5 more
wiley   +1 more source

Beyond Traditional Screening: The Future of Heart Failure Detection With Biomarkers and AI

open access: yesiNew Medicine, Volume 2, Issue 3, September 2026.
Advancing HF Screening: Integrating Technology and Risk Factors Across Eras. This diagram provides a comprehensive review of the historical developments and projected trends of heart failure (HF) screening methodologies, with the prevalent risk factors for HF depicted at the base.
Xiaofeng Fang   +9 more
wiley   +1 more source

Characterization of mesenchymal stem cells and CTNS(−/−) mutant target cells.

open access: yes, 2013
(a) FACS analysis (left) of bmMSC surface markers (blue) and isotype controls (red) and bmMSC differentiation from baseline (upper right) to Alizarin Red S-stained calcium-containing osteogenic (middle right) and Oil-Red O-stained adipocyte (bottom right)
Reyhan El-Kares (311952)   +13 more
core   +1 more source

Temporary VAT Reduction in Vietnam: Consumer Behavior Analysis

open access: yesInternational Studies of Economics, Volume 21, Issue 3, Page 249-263, September 2026.
ABSTRACT This study investigates the impact of temporary VAT rate changes on consumer behavior in Vietnam, particularly concerning the VAT reduction implemented during 2023–2024. The research analyzes annual survey data and household expenditure reports to assess changes in consumer spending on durable goods during the first half of 2024 (2024 H1 ...
Hang Thi Thu Trinh
wiley   +1 more source

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